Role of advanced glycation endproducts and potential therapeutic interventions in dialysis patients.

abstract：:Home hemodialysis is not a new therapy; rather it is a therapy in which interest has been rekindled due to both the continually growing end-stage renal disease population and concern about poor outcomes in patients on conventional thrice-weekly in-center dialysis. The practical issues to be considered when starting a ...

journal_title：Seminars in dialysis

authors： Moran J,Kraus M

更新日期：2007-01-01 00:00:00

abstract：:The risk of intradialytic hypotension (IDH) is determined by various factors, among them dialysis modality and dialyzer membrane. We conducted a literature search in PubMed on November 1, 2016 and selected relevant randomized controlled and cross-over trials, and prospective and retrospective cohort studies published ...

journal_title：Seminars in dialysis

authors： Patel S,Raimann JG,Kotanko P

更新日期：2017-11-01 00:00:00

abstract：:The treatment of chronically ill patients with end stage renal disease (ESRD) receiving dialysis therapies has advanced greatly over the years and accomplished many successes in prolonging the life of patients with ESRD, yet has had considerable failures due to the inability to compensate for all functions of the kidn...

journal_title：Seminars in dialysis

authors： Maddux FW

更新日期：2016-03-01 00:00:00

abstract：:Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. Although numerous modifiable risk factors in the pathogenesis of CVD and its associated mortality have been identified, dyslipidemia remains to be a key focus for therapy. In this regard, significant progress has been made in reducing ...

journal_title：Seminars in dialysis

authors： Moradi H,Streja E,Vaziri ND

更新日期：2018-07-01 00:00:00

abstract：:Concern over the inherent inefficiency of solute removal by conventional peritoneal dialysis (PD) has led to renewed interest in continuous flow PD (CFPD). We present clinical data from two experiences with CFPD. In the first, two catheters were used to recirculate a fixed intraperitoneal volume through an external ci...

journal_title：Seminars in dialysis

authors： Amerling R,DeSimone L,Inciong-Reyes R,Pangilinan A,Folden T,Ronco C,Gotch FA,Levin N

更新日期：2001-09-01 00:00:00

abstract：:There is abundant evidence that chronic renal failure (CRF) and end-stage renal disease (ESRD) alter drug disposition by affecting protein and tissue binding and reducing systemic clearance of renally cleared drugs. What is not fully appreciated is that CRF can significantly reduce nonrenal clearance and alter the bio...

journal_title：Seminars in dialysis

authors： Dreisbach AW,Lertora JJ

更新日期：2003-01-01 00:00:00

abstract：:The development of many electrolyte disturbances in the ICU can be prevented by attention to the use of intravenous fluids and nutrition. Hyponatremia is a relative contraindication to the use of hypotonic intravenous fluids and hypernatremia calls for the administration of water. Formulae have been devised to guide t...

journal_title：Seminars in dialysis

authors： Sedlacek M,Schoolwerth AC,Remillard BD

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to perform a comparative analysis of peritoneal dialysis catheter (PDC) insertion between blind and surgical methods by nephrologists. PATIENTS AND METHODS:The present study enrolled 249 peritoneal dialysis patients who received first-time PDC insertion. All PDC insertions w...

journal_title：Seminars in dialysis

authors： Kang SH,Park JW,Cho KH,Do JY

更新日期：2020-07-23 00:00:00

abstract：:Measurement of small molecule clearance remains important in the clinical care of patients requiring long-term dialysis. Many patients maintain a significant degree of residual native kidney function and may have nontraditional schedules with or without combined dialysis modalities. In this review, we examine and outl...

journal_title：Seminars in dialysis

authors： Chin AI,Depner TA,Daugirdas JT

更新日期：2017-05-01 00:00:00

abstract：:There is clear evidence that survival rates following transplantation far exceed those for remaining on dialysis, regardless of body size measured by body mass index (BMI). Studies over the past 15 years also suggest little to no difference in long-term outcomes, including graft survival and mortality, irrespective of...

journal_title：Seminars in dialysis

authors： MacLaughlin HL,Campbell KL

更新日期：2019-05-01 00:00:00

abstract：:There are numerous patient, provider, and health system barriers to accessing kidney transplantation. Patient barriers such as sociocultural and clinical characteristics and provider factors such as provider knowledge and awareness of transplantation play important roles in facilitating transplant. Health system facto...

journal_title：Seminars in dialysis

authors： Patzer RE,Pastan SO

更新日期：2020-01-01 00:00:00

abstract：:Continuous renal replacement therapy (CRRT) is commonly used in critically ill patients with acute kidney injury. Many studies show that compared with intermittent hemodialysis, continuous therapy has superior hemodynamic stability, metabolic clearance, and volume control. Despite these benefits, no survival advantage...

journal_title：Seminars in dialysis

authors： Finkel KW,Podoll AS

更新日期：2009-03-01 00:00:00

abstract：:The rationale of temperature control during hemodialysis (HD) is to prevent heat accumulation, which increases body temperature and enhances hypotensive susceptibility. Treatments where thermal energy is neither delivered nor removed from the patient through the extracorporeal circulation (so-called extracorporeal the...

journal_title：Seminars in dialysis

authors： Schneditz D,Ronco C,Levin N

更新日期：2003-11-01 00:00:00

abstract：:In the United States, presently there are more than 50,000 patients with end-stage renal disease (ESRD) awaiting a cadaveric kidney and each year less than a quarter receive kidney transplantation. Although the real incidence in unknown, a significant number of these patients die due to lack of dialysis access. While ...

journal_title：Seminars in dialysis

authors： Laskow DA,Ahsan N

更新日期：2002-01-01 00:00:00

abstract：:Pregnancy occurs uncommonly in women with chronic kidney disease (CKD) and fetal outcome tends to be poor, with high rates of prematurity and mortality. Dialysis, by complementing residual renal function, may improve fetal outcome in pregnant women with CKD. Although there are no prospective or randomized trials that ...

journal_title：Seminars in dialysis

authors： Shemin D

更新日期：2003-09-01 00:00:00

abstract：:A thorough consideration of all factors contributing to successful dialysis access creation is necessary to achieve optimal outcomes. A high bifurcation of the brachial artery (brachioradial variant) occurs in greater than 20% of patients. Dialysis access was created in 22 limbs with this variant--15 fistula, and 7 pr...

journal_title：Seminars in dialysis

authors： Kirksey L

更新日期：2011-11-01 00:00:00

abstract：:Withholding and withdrawal of dialysis has been a reality since dialysis was invented. Only in the past 20 years has it been formally studied, and we still have a great deal to learn. The nephrology community has slowly come to accept that, for some of our patients, not having dialysis is a better option than continui...

journal_title：Seminars in dialysis

authors： Germain MJ,Cohen LM,Davison SN

更新日期：2007-05-01 00:00:00

abstract：:Intravenous iron is an important component of the treatment of anemia of end-stage renal disease (ESRD), but it is biologically plausible that iron could increase the risk of infection through impairment of neutrophil and T-cell function and promotion of microbial growth. Any such increase in risk would be particularl...

journal_title：Seminars in dialysis

authors： Ishida JH,Johansen KL

更新日期：2014-01-01 00:00:00

abstract：:For patients who require hemodialysis, beta blockers offer a simultaneous opportunity and challenge in the treatment of cardiovascular disease. Beta blockers are well supported by data from nondialysis populations and directly mitigate the sympathetic overactivity that links chronic kidney disease with cardiovascular ...

journal_title：Seminars in dialysis

authors： Weir MA,Herzog CA

更新日期：2018-05-01 00:00:00

abstract：:Many dialysis machines can compute dialyzer sodium clearances at multiple time points during a dialysis treatment using conductivity. For a given treatment, the average dialyzer sodium clearance (K), when combined with treatment time (t), and the estimated urea distribution volume (V, usually based on either anthropom...

journal_title：Seminars in dialysis

authors： Daugirdas JT

更新日期：2018-11-01 00:00:00

abstract：:Continuous Renal Replacement Therapy (CRRT) usually requires anticoagulation to prevent clotting of the extracorporeal circuit. Interruptions due to filter clotting significantly reduce total therapy time and CRRT efficacy. Although heparin has traditionally been the most common anticoagulant used for CRRT, increasing...

journal_title：Seminars in dialysis

authors： Karakala N,Tolwani A

更新日期：2016-07-01 00:00:00

abstract：:The control of serum phosphorus by dialysis is made difficult by the fact that intradialytic blood levels tend to be low, and because phosphorus is removed almost exclusively from the plasma during its passage through the dialyzer. The most practical way to increase phosphorus removal is to extend dialysis time, altho...

journal_title：Seminars in dialysis

authors： Daugirdas JT

更新日期：2015-11-01 00:00:00

abstract：:In patients receiving hemodialysis, the provision of safe and effective vascular access using an arteriovenous fistula or graft is regarded as a critical priority by patients and health professionals. Vascular access failure is associated with morbidity and mortality, such that strategies to prevent these outcomes are...

journal_title：Seminars in dialysis

authors： Viecelli AK,Mori TA,Roy-Chaudhury P,Polkinghorne KR,Hawley CM,Johnson DW,Pascoe EM,Irish AB

更新日期：2018-05-01 00:00:00

abstract：:The dialysis industry is one of the most highly concentrated healthcare sectors in the United States. Despite decades of growth in the number of patients with end-stage renal disease and in the size of dialysis markets, two large dialysis organizations currently care for more than two-thirds of the dialysis population...

journal_title：Seminars in dialysis

authors： Saeed MK,Ho V,Erickson KF

更新日期：2020-01-01 00:00:00

abstract：:A good catheter implantation technique is important to allow for effective peritoneal access function and long-term technique survival. Studies regarding results obtained by nephrologists in comparison with surgeons have been limited to small single-center experiences. Thus, the objective of this study was to explore ...

journal_title：Seminars in dialysis

authors： de Moraes TP,Campos RP,de Alcântara MT,Chula D,Vieira MA,Riella MC,Olandowski M,Divino-Filho JC,Pecoits-Filho R,Investigators of BRAZPD.

更新日期：2012-09-01 00:00:00

abstract：:There has been a dramatic, worldwide expansion in life expectancy across the last century. This has resulted in a progressively more elderly and comorbid population. It is increasingly recognized that healthcare in this group needs to move to the concept of "adding life to years". Recognition and assessment of frailty...

journal_title：Seminars in dialysis

authors： Corbett RW,Brown EA

更新日期：2018-11-01 00:00:00

abstract：:The decision to provide dialytic support and choosing the ideal moment to initiate therapy are common impasses for physicians treating patients with acute kidney injury (AKI). Although renal replacement therapy (RRT) has been extensively used in clinical practice for more than 30 years, there is a paucity of evidence ...

journal_title：Seminars in dialysis

authors： Macedo E,Mehta RL

更新日期：2013-11-01 00:00:00

abstract：:While oral diuretics are commonly used in patients with chronic kidney disease for the management of volume and blood pressure, they are often discontinued upon initiation of dialysis. We suggest that diuretics are considerably underutilized in peritoneal dialysis and haemodialysis patients despite numerous potential ...

journal_title：Seminars in dialysis

authors： Trinh E,Bargman JM

更新日期：2016-09-01 00:00:00

abstract：:In response to rapid alkali delivery during hemodialysis, hydrogen ions (H+ ) are mobilized from body buffers and from stimulation of organic acid production in amounts sufficient to convert most of the delivered bicarbonate to CO2 and water. Release of H+ from nonbicarbonate buffers serves to back-titrate them to a m...

journal_title：Seminars in dialysis

authors： Sargent JA,Marano M,Marano S,Gennari FJ

更新日期：2019-05-01 00:00:00

abstract：:Early versus later start of dialysis is still a matter of debate. Low-protein diets have been used for many decades to delay dialysis initiation. Protein-restricted diets (0.3-0.6 g protein/kg/day) supplemented with essential amino acids and ketoanalogues (sVLPD) can be offered, in association with pharmacological tre...

journal_title：Seminars in dialysis

authors： Aparicio M,Bellizzi V,Chauveau P,Cupisti A,Ecder T,Fouque D,Garneata L,Lin S,Mitch W,Teplan V,Yu X,Zakar G

更新日期：2013-11-01 00:00:00