We Do Too Many Parathyroidectomies for Calciphylaxis.

Abstract:

:Calciphylaxis, a disorder of dermal arteriolar calcification with a distinct predilection for patients with advanced kidney disease, remains an enigmatic condition that challenges clinicians. Observations regarding positive associations between levels of circulating parathyroid hormone (PTH) and the risk of calciphylaxis, combined with experimental data suggesting a pathogenic role of secondary hyperparathyroidism in vascular calcification, have led to the assumption that reducing PTH levels will improve the outcomes in patients with calciphylaxis. This editorial communicates the contemporary data regarding surgical parathyroidectomy as a treatment option for these patients. We raise concerns regarding the quality of available data and discuss the direction of future comparative effectiveness research in this field.

journal_name

Semin Dial

journal_title

Seminars in dialysis

authors

Nigwekar SU,Sprague SM

doi

10.1111/sdi.12502

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

312-4

issue

4

eissn

0894-0959

issn

1525-139X

journal_volume

29

pub_type

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