Abstract:
BACKGROUND:Many children and adolescents with apparent bipolar disorder cannot be meaningfully diagnosed using the DSM-IV. The variety of pediatric bipolar phenotypes observed in clinical practice remains unclarified. METHOD:130 consecutively evaluated bipolar children and adolescents were assessed using semistructured clinical interviews and operational criteria that abandoned adherence to the DSM-IV cardinal symptom, duration of symptom persistence, and episodicity requirements. RESULTS:97.6% of the total sample manifested either all three, or two of the three symptoms elation, grandiosity, and racing thoughts, when manic. 96.9% of the total sample exhibited five or more of the eight DSM-IV criterion symptoms when manic. 52.3% of the subjects manifested ultradian cycling; 22.3% manifested chronic mania or chronic simultaneous manic mixed conditions. Only 21.5% could be classified within the Leibenluft et al. [Leibenluft, E., Charney, D.S., Towbin, K.E., Bhangoo, R.K., Pine, D.S., 2003. Defining clinical phenotypes of juvenile mania. Am. J. Psychiatry 160, 430-437.] system. Problematic distractibility-inattention was present in 89.9% and recurrent rage attacks in 48.5% of the total sample. Older subjects exhibited significantly more depressive symptoms, and nonsignificantly greater prevalences of major depression, severe depression, and ultradian cycling than did younger subjects. The number of depressive symptoms was significantly correlated with ultradian cycling. LIMITATIONS:This study relied upon retrospective as well as current reports of symptoms. The study results cannot be generalized to community samples. CONCLUSIONS:We propose two testable hypotheses: (1) that the recurrent, or chronic, simultaneous presence of any two of the symptoms elation, grandiosity, and racing thoughts and a total of five DSM-IV manic symptoms (without specific cardinal symptom, duration, or episodicity requirements) will identify nearly all clinic-referred bipolar children and adolescents; and (2) that a comprehensive classification of pediatric bipolar phenotypes based upon pattern of manic symptom episodicity or chronicity and degree of depression will identify subtypes of pediatric bipolar disorder that have greater correspondence with treatment response than do those of the DSM-IV classification. Problematic distractibility-inattention and explosive irritability-rage are highly prevalent; their presences should be specified when indicated.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Staton D,Volness LJ,Beatty WWdoi
10.1016/j.jad.2007.05.015subject
Has Abstractpub_date
2008-01-01 00:00:00pages
205-12issue
1-3eissn
0165-0327issn
1573-2517pii
S0165-0327(07)00197-8journal_volume
105pub_type
杂志文章abstract:BACKGROUND:Postnatal depression (PND) is a serious condition associated with negative consequences for the wellbeing of mother and infant. In the UK routine screening for PND is not currently recommended, although the use of two case finding questions in routine practice to identify PND has been advocated in policy gui...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2010.11.015
更新日期:2011-10-01 00:00:00
abstract::Differencing and cross-correlations are useful and straightforward methods for dealing with relationships between variables measured over short periods of time. Without such transformations of time-series data, spurious relationships may emerge and the true nature of underlying relationships may be obscured. This rean...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(90)90056-e
更新日期:1990-12-01 00:00:00
abstract::In a recent work by Liu et al. (2017) appeared in this journal, malondialdehyde levels proposed as a novel biomarker. Despite of wide usage of malondialdehyde as a biomarker, there are some points from analytical viewpoint which should be considered in future works. This work aimed to discuss the points briefly. ...
journal_title:Journal of affective disorders
pub_type: 评论,信件
doi:10.1016/j.jad.2017.07.050
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Transcranial direct current stimulation (tDCS) above the left dorsolateral prefrontal cortex (lDLPFC) has been widely used to improve symptoms of major depressive disorder (MDD). However, the effects of different stimulation protocols in the entire frontal lobe have not been investigated in a large sample in...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.02.077
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:An advantaged socioeconomic position (SEP) and satisfying social support during pregnancy (SSP) have been found to be protective factors of maternal postpartum depression (PDD). An advantaged SEP is also associated with satisfying SSP, making SSP a potential mediator of social inequalities in PPD. SEP, SSP a...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.04.024
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-adrenal (HPA) axis and depression but a causal relationship has not been established. This study aimed to evaluate the effects of vitamin D supplementation on depression severity, serum 25(OH)D, and some neurotransmitters in patie...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.029
更新日期:2020-05-15 00:00:00
abstract::The aim of this study was to examine the prospective relationship between pregnancy physical discomforts experienced during the second trimester and late pregnancy depressive symptoms, as well as the mediating effect of sleep quality on antenatal depressive symptomatology. Healthy pregnant women (N=257) completed the ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.09.015
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:The monitoring of patients with an anxiety disorder can benefit from Routine Outcome Monitoring (ROM). As anxiety disorders differ in phenomenology, several anxiety questionnaires are included in ROM: Brief Scale for Anxiety (BSA), PADUA Inventory Revised (PI-R), Panic Appraisal Inventory (PAI), Penn State W...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.031
更新日期:2013-09-25 00:00:00
abstract:BACKGROUND:Previous research has suggested that individuals tend to become more religious with age. Research has also shown that as individuals become more religious, they report decreases in depressive symptoms, suggesting that increased levels of religiosity might help to improve one's mental health. The following st...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2018.05.076
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Depression is one of the most common mental health problems in adolescents. A careful assessment of the prevalence and risk of depressive symptoms, as well as those factors that protect against it, is essential for prevention and intervention programs. METHOD:Using two waves of data from Grade 7 to Grade 9 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.05.034
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:Ethnic, social and cultural factors contribute to axis I comorbid conditions in bipolar disorder (BPD). Korea has strict laws against illicit drugs and a relatively permissive prevailing attitude toward alcohol. The present study aimed to explore the lifetime axis I comorbidity rate in patients with BPD in Ko...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.027
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnea (OSA) is a health hazard since it is associated with neurocognitive dysfunction and cardio-metabolic diseases. The prevalence of OSA among people with serious mental illness (SMI) is unclear. METHOD:We searched major electronic databases from inception till 06/2015. Articles were inc...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2016.02.060
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Cognitive reserve (CR) reflects the resilience of the brain to cope with neuropathological changes and minimize clinical manifestations. In the present study, we explore the association between CR and cognitive and psychosocial functioning, and examined the potential moderating role of CR in patients with bi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.09.019
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Self-poisoning and self-injury have widely differing incidences in hospitals and in the community, which has led to confusion about the concept of self-harm. Categorising self-harm simply by a method may be clinically misleading because many hospital-attending patients switch from one method of harm to anoth...
journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jad.2015.03.051
更新日期:2015-07-15 00:00:00
abstract::Thyrotropin secreting hormone (TSH) levels were recorded in baseline conditions and 20 and 60 min after thyrotropin releasing hormone (TRH) administration (200 micrograms i.v.) in 60 depressed females categorized according to DSM-III. Basal TSH (TSHB) and peak TSH responses (TSHP) were measured using ultrasensitive RI...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90075-x
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:It has been proposed that the broad major depressive disorder (MDD) construct is heterogenous. Koukopoulos has provided diagnostic criteria for an important subtype within that construct, "mixed depression" (MxD), which encompasses clinical pictures characterized by marked psychomotor or inner excitation and...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.01.025
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Cognitive compromise is a common experience for patients with depression and other mood disorders. Depressed patients sustain deficits in working memory and attentional distortions in emotional processing and negative attention biases, which may contribute to maintaining their depressive state. METHODS:The ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.08.080
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Previous researches showed a positive association between sugar-sweetened beverages (SSB) and behavioral problems, but there is a little known in Chinese preschoolers. METHODS:A population based survey was conducted in 109 kindergartens, in 11 cities across China. Children's SSB consumption was assessed by ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.01.076
更新日期:2020-03-15 00:00:00
abstract:BACKGROUND:The prevalence of antidepressant prescribing in children and adolescents increased steadily in the United States and parts of Europe between 2005 and 2012 despite regulatory safety warnings. Little is known about the characteristics of those being prescribed antidepressants for the first time. METHODS:A lon...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.12.047
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Depression and anxiety are prevalent psychiatric disorders that carry significant morbidity. Pharmacological and psychosocial interventions are used to manage these conditions, but their efficacy is limited. Recent interest into the use of psychedelic-assisted therapy using ayahuasca, psilocybin or lysergic ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.07.076
更新日期:2019-11-01 00:00:00
abstract::We used three rating scales to study diurnal variation of mood in 37 patients with major depressive disorder (17 drug-free patients and 20 treatment refractory patients on stable regimens of antidepressant medication). The three rating scales included global self-ratings administered twice a day; an itemized, prospect...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-0327(92)90016-y
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:The transition from adolescence to adulthood is associated with stressful adaptation experiences that may increase symptoms of depression. We explored the prevalence and sex differences of depressive symptoms and suicidal ideation in freshmen Latino college students in Puerto Rico, and identified stressful l...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.08.010
更新日期:2013-03-05 00:00:00
abstract:BACKGROUND:The Stroop interference test requires executive control functions, in particular inhibition of a learned routine (in this case word reading). Depressive patients show deficits on tests of executive function. However, the impact of confounding variables like type of depression and anxiety level is not yet elu...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.04.011
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Sympathetic nervous function abnormalities have long been suggested to be a possible etiology of panic disorder (PD). Catechol-O-methyltransferase (COMT) affects sympathetic activities, and the COMT Val(158)Met polymorphism has been suggested to be related to PD. The authors examined the relationship between...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.10.008
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:While major effort has been put in investigating neural correlates of depression and its treatment in adults, less is known about the effects of psychotherapy in adolescents. Given the concordance of the ventral striatum, amygdala, hippocampus and the subgenual anterior cingulate cortex (sgACC) as correlates...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.05.020
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Psychological distress symptoms are associated with an increased risk of psychiatric disorders and medical illness. Although psychological distress is influenced by environmental factors, such as socioeconomic status, lifetime events, or interpersonal relationships, substantial interindividual variation also...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.04.011
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Previous studies suggest that muscle-derived cytokines (myokines) are linked with brain function. Although muscle strength measured by handgrip strength is a prognostic indicator of functional decline, epidemiological studies directly examining the association between grip strength and mental health remain s...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.08.023
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Personality disorder (PD) may affect the efficacy of pharmacological interventions for mood disorders, but the extent to which this occurs is uncertain. We aimed to examine the available published evidence concerning the role of PD in pharmacological treatment outcomes of randomised controlled trials (RCTs) ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2020.10.031
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:We aimed to examine differential effects of WMH on progression of depressive symptoms according to APOE ε4 status in the elderly. METHODS:We obtained data from elderly Korean subjects (n=707) aged 60 years or older at baseline from the CREDOS study from November 2005 to July 2014. A linear mixed model strat...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.08.032
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Although panic disorder (PD) is suggestive of autonomic nervous system dysfunction, especially in the cardiovascular autonomic system (CAS), the results in many previous studies are still controversial. Using a new physiological index which could well reflect emotional reaction to visual stimuli (Yoshizawa, ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2004.03.008
更新日期:2004-11-01 00:00:00