Abstract：
:Early onset blindness allows one to investigate how the human brain adapts to sensory experience in infancy and early childhood. Over the past decade, lesion, functional and structural imaging studies have accumulated evidence that severe perturbations to visual experience alter the functional and structural organization of the human brain. Visual deprivation can induce plastic changes not only in the visual system, but also in the remaining intact sensory-motor system, secondary to altered experience using these spared modalities. In particular, occipital, usually visual, areas are reorganized and recruited by the remaining senses and higher cognitive tasks primarily through cortico-cortical connectivity. Importantly, these plastic changes vary as a function of timing and are most pronounced in early onset blindness. Thus, sensory experience shapes functional and structural brain organization during sensitive periods in neurodevelopment.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Noppeney Udoi
10.1016/j.neubiorev.2007.04.012subject
Has Abstractpub_date
2007-01-01 00:00:00pages
1169-80issue
8eissn
0149-7634issn
1873-7528pii
S0149-7634(07)00057-7journal_volume
31pub_type
杂志文章,评审abstract：:Recently our group forwarded a model of speed-accuracy relations in goal-directed reaching. A fundamental feature of our multiple process model was the distinction between two types of online regulation: impulse control and limb-target control. Impulse control begins during the initial stages of the movement trajector...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.11.016
更新日期：2017-01-01 00:00:00
abstract：:Vago-vagal reflex control circuits in the dorsal vagal complex of the brainstem provide overall coordination over digestive functions of the stomach, small intestine and pancreas. The neural components forming these reflex circuits are under significant descending neural control. By adjusting the excitability of the d...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(95)00040-l
更新日期：1996-01-01 00:00:00
abstract：:Modern functional imaging methods, such as positron emission tomography (PET) and single photon emission computed tomography (SPECT), provide non-invasive, quantitative tools for the direct measurement of neurotransmitter function in the living human brain. The dopamine system has been of key interest; first, because ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(02)00065-9
更新日期：2002-11-01 00:00:00
abstract：:The existence of a close relationship between psychosocial factors and cardiovascular morbidity is not just a hypothesis anymore. Research on humans has been attempting to unravel the significance of this association by investigating psychological and social characteristics in relation to cardiovascular health. Howeve...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.12.005
更新日期：2014-02-01 00:00:00
abstract：:Early studies of hypothalamic function found that damage to the ventromedial hypothalamus (VMH) resulted in marked overeating but inferior performance in food-motivated tasks, leading several investigators to conclude that hyperphagic VMH animals were actually less hungry than normal animals. However, numerous studies...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(80)90013-5
更新日期：1980-07-01 00:00:00
abstract：:Persistent, unwanted memories are believed to be key contributors to drug addiction and the chronic relapse problem over the lifetime of the addict. Contrary to the long-held idea that memories are static and fixed, new studies in the last decade have shown that memories are dynamic and changeable. However, they are c...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2012.02.004
更新日期：2012-05-01 00:00:00
abstract：:Among terrestrial mammals, elephants share the unique status, along with humans and great apes, of having large brains, being long-lived and having offspring that require long periods of dependency. Elephants have the largest brains of all terrestrial mammals, including the greatest volume of cerebral cortex. In contr...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2007.05.012
更新日期：2008-01-01 00:00:00
abstract：:One obstacle to understanding the exact processes unfolding inside the hippocampus is that it is still difficult to clearly define what the hippocampus actually does, at the system level. Associated for a long time with the formation of episodic and semantic memories, and with their temporary storage, the hippocampus ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2011.12.002
更新日期：2012-08-01 00:00:00
abstract：:A basic aspect of the neuronal control of bipedal stance and gait represents the antigravity function of leg extensors. Proprioceptive reflexes involved in the maintenance of body equilibrium depend on the presence of contact forces opposing gravity. Extensor load receptors are thought to signal changes of the project...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(97)00035-3
更新日期：1998-07-01 00:00:00
abstract：:Dementia is a major cause of disability amongst the elderly and represents a serious global health issue. Current treatments for dementia are limited; at best they provide inadequate symptomatic relief. In contrast, there are a plethora of approaches that provide symptomatic relief for abnormalities of movement includ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.09.003
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVES:Repetitive transcranial magnetic stimulation (rTMS) is a potential therapeutic intervention for the treatment of addiction. This critical review aims to summarise the recent developments with respect to the efficacy of rTMS for all types of addiction and related disorders (including eating disorders), and co...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2014.10.013
更新日期：2014-11-01 00:00:00
abstract：:Prompted by recent findings suggesting that the basal ganglia and possibly the limbic midbrain area and brainstem reticular formation may be represented within the general learning system of the rat brain, the current study was undertaken to assess the learning ability of different groups of young rats prepared with b...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(87)80011-8
更新日期：1987-01-01 00:00:00
abstract：:In this review, we have summarized various aspects as to how prenatal protein malnutrition affects development of the brain and have attempted to integrate several broad principles, concepts, and trends in this field in relation to our findings and other studies of malnutrition insults. Nutrition is probably the singl...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80234-9
更新日期：1993-04-01 00:00:00
abstract：:Cardiometabolic risk factors may be of key importance in the development of future brain diseases like dementia or depression. However, it remains unclear how these risk factors exactly affect the brain. Advanced MR imaging methods such as, diffusion weighted and functional MRI, can provide detailed insights into subt...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2020.04.001
更新日期：2020-08-01 00:00:00
abstract：:We propose to bring together the hitherto rather separate research fields of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), and argue that by contrasting and combining findings of the endophenotypes of ASD and ADHD new insights can be gained into the etiology and pathophysiology of...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2011.02.015
更新日期：2011-05-01 00:00:00
abstract：:The possible implication of 5-HT2 receptors in CNS disorders such as schizophrenia, anxiety and depression suggests that 5-HT2 antagonists may be useful in the treatment of these disorders. The present review examines behavioral procedures used to characterize 5-HT2 antagonist properties of compounds and behavioral mo...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80056-9
更新日期：1992-04-01 00:00:00
abstract：:About 2-3% of all children are affected by mental retardation, and genetic conditions rank among the leading causes of mental retardation. Alterations in the information encoded by genes that regulate critical steps of brain development can disrupt the normal course of development, and have profound consequences on me...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(03)00016-2
更新日期：2003-01-01 00:00:00
abstract：:Two major consequences of placentophagia, the ingestion of afterbirth materials that occurs usually during mammalian parturition, have been uncovered in the past several years. The first is that increased contact, associated with ingesting placenta and amniotic fluid from the surface of the young, causes an accelerate...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80035-1
更新日期：1991-10-01 00:00:00
abstract：:Adolescence as highlighted in this special issue is a period of tremendous growth, synaptic exuberance, and plasticity, but also a period for the emergence of mental illness and addiction. This commentary aims to stimulate research on prevention science to reduce the impact of early life events that often manifest dur...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/j.neubiorev.2016.07.012
更新日期：2016-11-01 00:00:00
abstract：:In the past few years, several experimental studies have suggested that empathy occurs in the social lives of rodents. Thus, rodent behavioral models can now be developed to elucidate the mechanistic substrates of empathy at levels that have heretofore been unavailable. For example, the finding that mice from certain ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2011.05.013
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Children and adolescents with conduct disorder (CD) show repetitive and persistent patterns of aggressive behaviour and the more severe forms are often associated with callous-unemotional (CU) traits. OBJECTIVES:To systematically review and, where data are adequate, conduct meta-analyses on the efficacy of ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析
doi：10.1016/j.neubiorev.2017.01.024
更新日期：2018-08-01 00:00:00
abstract：:Pathological dissociation is a severe, debilitating and transdiagnostic psychiatric symptom. This review identifies biomarkers of pathological dissociation in a transdiagnostic manner to recommend the most promising research and treatment pathways in support of the precision medicine framework. A total of 205 unique s...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2020.11.019
更新日期：2020-11-30 00:00:00
abstract：:Efforts to determine and understand the causes of autism are currently hampered by a large disconnect between recent molecular genetics findings that are associated with the condition and the core behavioral symptoms that define the condition. In this perspective piece, we propose a systems biology framework to bridge...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2014.10.006
更新日期：2015-03-01 00:00:00
abstract：:The intent of this paper is to evaluate decreases of food intake and body weight that occur when a peptide is administered to an animal. Using the pancreatic hormone insulin as an example, the case is made that endogenous insulin is normally secreted in response to circulating nutrients as well as in proportion to the...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(95)00044-f
更新日期：1996-01-01 00:00:00
abstract：:The potential for the coexistence of the developmental disorders autism and attention-deficit/hyperactivity disorder (ADHD) in any one individual has for a long time been a contentious issue. While from a neurobiological perspective it is possible, and even highly likely, that ADHD and autism might clinically co-exist...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/j.neubiorev.2010.11.002
更新日期：2011-04-01 00:00:00
abstract：:Human adolescence is a time of enormous developmental change, second only to infancy and early childhood in terms of brain shaping and growth. It is also a period in life when the young adult is faced with distinct environmental challenges and stressors. Interestingly, we now know that these external sources of stress...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.06.005
更新日期：2016-11-01 00:00:00
abstract：:Rapid instructed task learning (RITL) is one of the most remarkable human abilities, when considered from both computational and evolutionary perspectives. A key feature of RITL is that it enables new goals to be immediately pursued (and shared) following formation of task representations. Although RITL is a form of c...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2017.02.009
更新日期：2017-10-01 00:00:00
abstract：:Human adolescence has been characterized by increases in risk-taking, emotional lability, and deficient patterns of behavioral regulation. These behaviors have often been attributed to changes in brain structure that occur during this developmental period, notably alterations in gray and white matter that impact synap...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2009.12.007
更新日期：2010-04-01 00:00:00
abstract：:Pupillometry, measuring pupil size and reactivity, has been proposed as a measure of autonomic nervous system functioning, the latter which might be altered in individuals with autism spectrum disorder (ASD). This study aims to evaluate if pupillary responses differ in individuals with and without ASD. After performin...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2020.09.032
更新日期：2020-10-22 00:00:00
abstract：:We investigated whether genetic differences in various forms of intraspecific aggression and anxiety in four different genetic lines of mice (i.e. wild, outbred Swiss-CD1, inbred DBA/2 and inbred C57/BL6N) may reflect modifications in behavioral strategy. Experiments 1 and 2 used ethologically based paradigms to analy...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(99)00029-9
更新日期：1999-11-01 00:00:00
