Abstract：
:Male rats received normal chow or high-fat diets rich in dextrose (HFD) or sucrose (HFS). Half of the rats received 90-day unrestricted access to their diet prior to training, whereas the other half were food restricted throughout the study. We evaluated the effects of these dietary manipulations on discrimination and reversal performance and on post-training levels of brain-derived neurotrophic factor (BDNF) in the prefrontal cortex and the ventral and dorsal hippocampus. Neither diet nor restriction condition affected discrimination acquisition. However, prior unrestricted access to the HFD diet impaired discrimination reversal learning and reduced BDNF in the prefrontal cortex and ventral hippocampus. Also, rats given the HFD diet responded more than controls to the previously rewarded cue at the outset of discrimination reversal. The results suggest that consumption of the HFD diet may have had enduring effects on learning processes, some of which may contribute to the control of intake regulation.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Kanoski SE,Meisel RL,Mullins AJ,Davidson TLdoi
10.1016/j.bbr.2007.05.004subject
Has Abstractpub_date
2007-08-22 00:00:00pages
57-66issue
1eissn
0166-4328issn
1872-7549pii
S0166-4328(07)00251-3journal_volume
182pub_type
杂志文章abstract：:Sensorimotor performance is highly dependent on the level of physical activity. For instance, a period of disuse induces an impairment of motor performance, which is the result of combined muscular, spinal and supraspinal mechanisms. Concerning this latter origin, our hypothesis was that intrinsic properties and input...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2010.02.006
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abstract：:Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of research in which a number of key technologies converge: in particular, identification of putative susceptibility genes through associat...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
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abstract：:Granular cell proliferation in the adult hippocampus decreases during aging and after chronic stress, while it can be increased by physical activity or treatment with the antidepressant fluoxetine. We investigated whether the physical and cognitive stimulation accompanied by stress in the commonly used Morris water ma...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2005.04.013
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journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(93)90017-k
更新日期：1993-07-30 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(80)90034-0
更新日期：1980-06-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2007.07.017
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abstract：PURPOSE:To explore the effect of vagal nerve stimulation (VNS) on spontaneous brain activity in patients with drug-resistant epilepsy (DRE). METHODS:15 patients and eight healthy controls (HC) were enrolled and scanned by resting-state functional MRI to investigate changes in the fractional amplitude of low-frequency ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2020.112709
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journal_title：Behavioural brain research
pub_type： 杂志文章
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90076-9
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.03.039
更新日期：2015-01-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.06.006
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2018.07.018
更新日期：2018-11-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章,评审
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(03)00075-5
更新日期：2003-07-14 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2020.113104
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(02)00422-9
更新日期：2003-06-16 00:00:00
abstract：:The efferent and afferent connections of the V1/V2 border with the contralateral hemisphere have been examined using anatomical tracers. The V1/V2 border was found to exchange connections with the contralateral V2 area as well as a restricted strip of V1 lying adjacent to the V1/V2 border. Besides these homotopic proj...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90027-7
更新日期：1988-08-01 00:00:00
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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doi：10.1016/j.bbr.2011.05.008
更新日期：2011-10-31 00:00:00
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更新日期：2021-01-06 00:00:00
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2006.04.006
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.04.011
更新日期：2011-09-30 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(96)00014-9
更新日期：1996-09-01 00:00:00
abstract：:In the present study, we investigated the involvement of prefrontal glutamatergic neurotransmission in the enhancement of immobility (emotional deficit) in a forced swimming test in mice treated with phencyclidine (PCP: 10mg/kg/day for 14 days) repeatedly, which is regarded as an animal model for negative symptoms. A ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2007.03.003
更新日期：2007-06-18 00:00:00
