Central adiposity and atherogenic lipids in Saudi diabetics.

Abstract:

:A high caloric intake from fat sources and prevailing obesity in the Saudi population prompted this study. Waist to hip circumference ratio (WHR), fasting cholesterol, triglycerides and insulin were measured in 76 non-insulin dependent adult Saudi diabetics. Serum LDL, HDL and VLDL were measured in 45 of these diabetics. WHR of Saudi diabetics was higher (0.98 in males, 0.91 in females) than reported for diabetics from the West. Serum cholesterol levels (5.52 mmol/L in males, 5.98 mmol/l in females) were higher than reported in the past for normal Saudi subjects. Lipid profile was strikingly different in the two sexes. Male diabetics (n=28) had significantly higher WHR associated with elevated triglycerides and VLDL but a lower HDL/cholesterol ratio. Female diabetics (n=48) were obese and had healthier HDL levels. Interestingly, LDL cholesterol changed reciprocally with WHR in female diabetics. This preliminary study reveals the presence of significant central adiposity and an atherogenic lipid profile in Saudi diabetics. The sex differences in lipids indicates the need for studies involving lipoprotein metabolism in Saudis. Further, an increase in atherosclerosis-related disorders should be expected in Saudi diabetics.

journal_name

Ann Saudi Med

journal_title

Annals of Saudi medicine

authors

Khandekar S,Noeman SA,Muralidhar K,Gadallah M,Al-Sawaf KS

doi

10.5144/0256-4947.1994.329

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

329-32

issue

4

eissn

0256-4947

issn

0975-4466

pii

14-329

journal_volume

14

pub_type

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