Prevalence of antibodies to hepatitis C virus in Saudi patients with chronic liver disease.


:The prevalence of antibodies to hepatitis C virus (anti-HCV) has been measured in 113 Saudi patients with chronic liver diseases. Twenty-five percent of 20 patients with hepatocellular carcinoma (HCC) were positive for anti-HCV and 29.7% of 38 patients with cirrhosis and 27.3% of 33 patients with liver fibrosis, respectively, also tested positive. The positivity rate for a miscellany of liver diseases (22) was 13.6%. The differences between these prevalence rates were not statistically significant. By comparison, 45% of HCC tested positive for hepatitis B surface antigen (HBsAg) while 52.7% of cirrhosis cases were positive. There rates were statistically significant when compared with HBsAg positivity rates of 9.1% and 18.2% in the liver fibrosis and miscellaneous groups. The role of hepatitis C virus (HCV) may be secondary or additive in the causation of chronic liver disease and hepatocellular carcinoma in this environment in which hepatitis B virus (HBV) is highly endemic.


Ann Saudi Med


Annals of Saudi medicine


Fakunle YM,Al-Mofarreh M,El-Drees AZ,El-Karamany WM,Ezzat HO,Ballesteros MN,Khawaji MZ




Has Abstract


1991-09-01 00:00:00














  • Clinicopathological study of male breast carcinoma: 24 years of experience.

    abstract:BACKGROUND AND OBJECTIVES:Because breast cancer in men is rare, few patients are available for prospective studies. To learn more about its epidemiology, risk factors, clinical features, genetics and pathology in our country, we conducted a retrospective study of all cases seen in recent decades at our institution. PA...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Shah P,Robbani I,Shah O

    更新日期:2009-07-01 00:00:00

  • Clinical and radiological characteristics of Chinese patients with hepatic epithelioid hemangioendothelioma.

    abstract:BACKGROUND AND OBJECTIVES:To study clinical features, imaging findings, and prognosis of hepatic epithelioid hemangioendothelioma (HEHE) in Eastern Hepatobiliary Surgical Hospital and to improve the level of recognition and preoperative diagnosis of HEHE. DESIGN AND SETTINGS:This is a retrospective study. The study wa...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Fan F,Yang X,Zhu B,Zhang Y

    更新日期:2013-07-01 00:00:00

  • Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt.

    abstract:BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause a spectrum of hemolytic manifestations. OBJECTIVE:To determine the local prevalence of G6PD deficiency in newborns. DESIGN:Cross-sectional. SETT...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Elella SA,Tawfik M,Barseem N,Moustafa W

    更新日期:2017-09-01 00:00:00

  • Trihexyphenidyl (artane) abuse among Saudi psychiatric patients.

    abstract::This preliminary study done by abstracting relevant data from different testing material and using multiple rating scales, describes the sociodemographic variables, psychopathological correlates, and features of trihexyphenidyl (artane) abuse in a sample of 14 Saudi psychiatric patients and, as a result of this resear...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Qureshi NA

    更新日期:1992-07-01 00:00:00

  • Pulse cyclophosphamide therapy for steroid-resistant focal segmental glomerulosclerosis in children.

    abstract:BACKGROUND:In children, steroid-resistant nephritic syndrome due to focal segmental glomerulosclerosis (FSGS) is frequently a progressive condition resulting in end-stage renal disease (ESRD). We report the response of 15 patients with steroid resistant FSGS to treatment with intravenous pulse cyclophosphamide (IVCP) a...

    journal_title:Annals of Saudi medicine

    pub_type: 临床试验,杂志文章


    authors: Al Salloum AA

    更新日期:2004-01-01 00:00:00

  • Assessment of hepatitis B immunization status after antineoplastic therapy in children with cancer.

    abstract:BACKGROUND AND OBJECTIVES:Hepatitis B is a disease that is preventable with vaccination. Antibody levels after vaccination may be affected by suppression of the immune system due to cancer therapy. Children with cancer have a high risk of hepatitis B virus (HBV) infection. We aimed to assess the pretreatment immunizati...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Karaman S,Vural S,Yildirmak Y,Urganci N,Usta M

    更新日期:2011-11-01 00:00:00

  • Epidemiology of sickle cell disease in Saudi Arabia.

    abstract::Sickle cell disease (SCD) is an autosomal recessive disorder characterized by production of abnormal hemoglobin S and is associated with high morbidity and mortality. Information about the prevalence of SCD in Saudi Arabia is patchy and probably underestimated, but studies have reported that SCD is a relatively common...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,评审


    authors: Jastaniah W

    更新日期:2011-05-01 00:00:00

  • Predictive value of the cow's milk skin prick test in infantile colic.

    abstract:BACKGROUND AND OBJECTIVES:Infantile colic is a common problem among young infants. Cow's milk allergy has been suggested as one of the causes. We aimed to investigate the value of the cow's milk skin test for the diagnosis of cow's milk allergy in exclusively breast-fed infants with infantile colic. METHODS:Exclusivel...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,随机对照试验


    authors: Moravej H,Imanieh MH,Kashef S,Handjani F,Eghterdari F

    更新日期:2010-11-01 00:00:00

  • Changing pattern of hepatitis viral infection in Saudi Arabia in the last two decades.

    abstract:BACKGROUND:Information on the epidemiology of viral hepatitis B, C and A in the Kingdom of Saudi Arabia (KSA) has accumulated over the last two decades. We review the changing epidemiology of these infections and suggest possible strategies for eradication. METHODS:We screened Saudi medical journals and Medline for re...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Al-Faleh FZ

    更新日期:2003-11-01 00:00:00

  • Extracorporeal shock wave lithotripsy in the treatment of ureteric stones: experience from Tawam Hospital, United Arab Emirates.

    abstract:BACKGROUND:The optimal treatment of ureteric stones, especially the lower ureteric stone, remains controversial. The purpose of this study was to evaluate the role of extracorporeal shock wave lithotripsy (ESWL) in the management of ureteric stones. MATERIALS AND METHODS:A total of 99 patients with ureteric stones at ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Ghafoor M,Halim A

    更新日期:2002-01-01 00:00:00

  • Steroid therapy for post-tonsillectomy symptoms in adults: a randomized, placebo-controlled study.

    abstract:BACKGROUND:Post-operative morbidity following tonsillectomy remains an important clinical problem despite advances in anesthetic and surgical techniques. This study investigated the effect of a one-day course of intravenous dexamethasone on recovery from tonsillectomy. PATIENTS AND METHODS:In a double-blind, randomize...

    journal_title:Annals of Saudi medicine

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Al-Shehri AM

    更新日期:2004-09-01 00:00:00

  • Neural tube defects in Southwestern region of Saudi Arabia.

    abstract::During December 1987 to December 1990 the incidence of neural tube defects in the Asir region located in southwestern Saudi Arabia was 0.82/1000. These results were drawn from a survey conducted of all cases of neural tube defects referred to the main hospital at Abha City (Asir Central Hospital) (ACH). Anencephaly wa...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: El-Awad Mel-H,Sivasankaran S

    更新日期:1992-09-01 00:00:00

  • Experience with living related donor nephrectomy: Evaluation of 200 cases.

    abstract::Over a ten year period (1979 to 1989), 200 patients have undergone live donor nephrectomy through a flank extraperitoneal approach without rib resection. The average hospital stay was short and the major complications were negligible. Early graft function was seen in 97% of the cases. Delayed function due to acute tub...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Abomelha MS,Assari S,Shaaban A,Al-Otaibi K,Kourah M

    更新日期:1993-09-01 00:00:00

  • Etiology of upper gastrointestinal bleeding in Jordanian patients: A prospective study.

    abstract::Endoscopy within 24 hours from the onset of upper gastrointestinal (UGI) bleeding was carried out on 853 Jordanian patients. Lesions as a bleeding source were identified in 799 (93.7%) patients. Radioactively tagged red blood cell (RBC) scan, angiography and upper gastrointestinal follow-through radiography were compl...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Shennak MM

    更新日期:1995-01-01 00:00:00

  • A novel splice-site mutation in the ASPM gene underlies autosomal recessive primary microcephaly.

    abstract:BACKGROUND:Autosomal recessive primary microcephaly (MCPH) is a clinically and genetically heterogeneous disorder. Patients with MCPH exhibit reduced occipito-frontal head circumference and non-progressive intellectual disability. To date, 17 genes have been known as an underlying cause of MCPH in humans. ASPM (abnorma...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Hashmi JA,Al-Harbi KM,Ramzan K,Albalawi AM,Mehmood A,Samman MI,Basit S

    更新日期:2016-11-01 00:00:00

  • Levels of the first-phase insulin secretion deficiency as a predictor for type 2 diabetes onset by using clinical-metabolic models.

    abstract:AIMS:Type 2 diabetes mellitus (T2DM) is characterized by both decreased insulin sensitivity and impaired insulin secretion. The 2 phases of insulin secretion are the first-phase insulin secretion (1st ISEC) and the second-phase insulin secretion. In this study, we tried to build clinical-metabolic models to predict the...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Lin JD

    更新日期:2015-03-01 00:00:00

  • Myxopapillary ependymoma masquerading as subcutaneous sacrococcygeal non-healing ulcer: case report.

    abstract::Ependymomas outside the confines of the cranium and spinal cord are rare. The occurrence of these tumors in an extradural, sacrococcygeal, or subcutaneous location may prove challenging, particularly in the absence of any obvious central nervous system connection. The origin of these tumors from sub.cutaneous sacrococ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Zaidi SN,AlKhalidi H,Al-Rikabi AC

    更新日期:2014-05-01 00:00:00

  • Saudi Heart Rhythm Society Task Force on Management of Potential Arrhythmogenicity Associated with Pharmacotherapy for COVID-19.

    abstract::Evidence of cardiovascular complications associated with the COVID-19 global pandemic continues to evolve. These include direct and indirect myocardial injury with subsequent acute myocardial ischemia, and cardiac arrhythmia. Some results from a limited number of trials of antiviral medications, along with chloroquine...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,评审


    authors: AlShoaibi NA,Maghrabi K,Alanazi H,Harbi MA,Alghamdi S

    更新日期:2020-09-01 00:00:00

  • Measles vaccine failure.

    abstract::Suleimania Children's Hospital, Riyadh, Saudi Arabia was the site of a on-year study, started June 1987, which was designed to investigate measles vaccine failure. The first part of the study consisted of 336 patients with measles. Diagnosis was established on clinical grounds and confirmed by fluorescent IgM analysis...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Abanamy A,Khalil M,Salman H,Abdulazeem M

    更新日期:1991-05-01 00:00:00

  • Grading of follicular lymphoma using flow cytometry.

    abstract:BACKGROUND:The treatment and prognosis of follicular lymphoma (FL) is dependant on the grade of the disease. In the World Health Organization classification of lymphoma, grading of FL into low grade (1 and 2) and high grade (3) is recommended. Grading of FL is possible in excision biopsy; histological grading is subjec...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Mourad WA,Rawas F,Shoukri M,Tbakhi A,Al Omari M,Tulbah A,Al Dayel F

    更新日期:2006-05-01 00:00:00

  • In vitro-activated tumor-bearing host T cells and the effectiveness of tumor vaccine immunotherapy.

    abstract:BACKGROUND AND OBJECTIVE:Vaccination during periods of lymphopenia may facilitate immune responses to weak self-antigens and enhance antitumor immunity. The objective of this study was to determine the effectiveness of tumor vaccine immunotherapy combined with immune reconstruction using tumor-bearing host immune cells...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Li QL,Gao SF,Wang YP,Ma J,Feng CX,Wang Y,Wang YL

    更新日期:2012-03-01 00:00:00

  • Head and neck cancer in a referral center in Asir region.

    abstract::This study looks at the incidence of head and neck cancer in the Southwest Region of the Kingdom of Saudi Arabia (Asir Region). There were a total of 204 newly diagnosed patients seen at Asir Central Hospital between 1987 and 1992; 113 males and 91 females. All were Saudi patients. Frequency at various sites with refe...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Al-Ghamdi SA,Malatani T,Kameswaran M,Khurana P

    更新日期:1994-09-01 00:00:00

  • General anesthesia for cataract surgery: Experience at King Fahd Hospital of the University, Al-Khobar.

    abstract::Although cataract surgery is increasingly being performed under local anesthesia in many centers, general anesthesia is preferred for cataract surgery at the King Fahd Hospital of the University (KFHU), Al-Khobar. Ninety two patients who had cataract extraction under general anesthesia at KFHU between October 1988 and...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Umeh B,Tamimi E

    更新日期:1992-01-01 00:00:00

  • Hair tourniquet syndrome.

    abstract::The hair tourniquet syndrome is a rare disorder. This syndrome has been described as involving the fingers, the toes and even the genitals. We report a case of hair tourniquet syndrome affecting multiple toes of an infant. After the hair fiber was removed there was a fast healing period and no signs of tissue necrosis...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Cevik Y,Kavalci C

    更新日期:2010-09-01 00:00:00

  • Zinc and antioxidant vitamin deficiency in patients with severe sickle cell anemia.

    abstract:BACKGROUND:Patients with severe sickle cell anemia (SCA) have a higher potential for oxidative damage due to chronic redox imbalance in red blood cells that often leads to hemolysis, endothelial injury and recurrent vaso-occlusive episodes. This study evaluated the plasma levels of vitamins A, C and E as indicators of ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Hasanato RM

    更新日期:2006-01-01 00:00:00

  • Implementation of total laboratory automation at a tertiary care hospital in Saudi Arabia: effect on turnaround time and cost efficiency.

    abstract:BACKGROUND:Total laboratory automation (TLA) is a relatively new way of improving the management of high volume clinical laboratories. TLA may reduce staff, reduce operating costs, decrease testing time and provide enhanced process control. OBJECTIVES:Establish a cost efficient TLA that is less labor intensive, improv...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Ellison TL,Alharbi M,Alkaf M,Elimam S,Alfaries M,Nounou RA,Nasr R,Owaidah T

    更新日期:2018-09-01 00:00:00

  • Outcomes of road traffic injuries before and after the implementation of a camera ticketing system: a retrospective study from a large trauma center in Saudi Arabia.

    abstract:BACKGROUND:Road traffic injuries (RTIs) are the third leading cause of death in Saudi Arabia. Because speed is a major risk factor for severe crash-related injuries, a camera ticketing system was implemented countrywide in mid-2010 by the traffic police in an effort to improve traffic safety. There are no published stu...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Alghnam S,Alkelya M,Alfraidy M,Al-Bedah K,Albabtain IT,Alshenqeety O

    更新日期:2017-01-01 00:00:00

  • Reproductive health profile and circumcision of females in the Hali semi-urban region, Saudi Arabia: A community-based cross-sectional survey.

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    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Milaat WA,Ibrahim NK,Albar HM

    更新日期:2018-03-01 00:00:00

  • Geographical distribution of congenital heart defects in Saudi Arabia.

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    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Greer W,Sandridge AL,Al-Menieir M,Al Rowais A

    更新日期:2005-01-01 00:00:00

  • Burden of traumatic injuries in Saudi Arabia: lessons from a major trauma registry in Riyadh, Saudi Arabia.

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    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章


    authors: Alghnam S,Alkelya M,Al-Bedah K,Al-Enazi S

    更新日期:2014-07-01 00:00:00