Pattern of adult onset of polymyositis and dermatomyositis and association with malignancy.

Abstract:

:A retrospective study of 22 adult patients with dermatomyositis (DM) or polymyositis (PM) was performed. Male to female ratio was 1:2.7. Mean age of onset was 37.3 +/- (16.3) and symptoms were present for a mean of 11.2 +/- 14.6 months before diagnosis. Primary polymyositis was diagnosed in 11 (50%), primary dermatomyositis in three (13.6%). PM/DM was associated with connective tissue disease in three (13.6%) and malignancy in five patients (22.7%). Muscle disease followed the diagnosis of malignancy by a mean of 12.2 months (one to 36 months). All were female. Diffuse erythema was observed in all three patients with DM and malignancy. Arthritis was seen more frequency in our patients (55%). Sixty-eight percent of patients showed substantial improvement of muscle disease with steroids alone or in combination with other immunosuppressive agents, 18% did not improve or their disease progressed in spite of the treatment. Three patients died (14%), two from respiratory failure and one from underlying malignancy.

journal_name

Ann Saudi Med

journal_title

Annals of Saudi medicine

authors

Al-Ballaa ST,Al-Dalaan AN,El-Ramahi KM,Al-Janadi MA,Al-Shaikh A,Bahabri S

doi

10.5144/0256-4947.1993.525

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

525-9

issue

6

eissn

0256-4947

issn

0975-4466

pii

13-525

journal_volume

13

pub_type

杂志文章
  • Reproductive health profile and circumcision of females in the Hali semi-urban region, Saudi Arabia: A community-based cross-sectional survey.

    abstract:BACKGROUND:Improving the reproductive health of females has be.come the focus of the developmental efforts of many nations. OBJECTIVES:To identify the reproductive health style of married females, and to determine the prevalence and predictors of circumcision among girls aged less than or equal 18 years in Hali semi-u...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2018.81

    authors: Milaat WA,Ibrahim NK,Albar HM

    更新日期:2018-03-01 00:00:00

  • Enteric fever due to multi-resistant Salmonella typhi.

    abstract::Five cases of enteric fever due to multi-resistant Salmonella typhi are reported. Four of these patients most probably contracted the disease in India and the fifth in Egypt. All of them were successfully treated either with ceftriaxone or ciprofloxacin. ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1993.246

    authors: Kambal AM,Al-Sugair S,Al-Ballaa SR,Al-Hedaithy M,Al-Balla SR,Saeed NS

    更新日期:1993-05-01 00:00:00

  • Burden of traumatic injuries in Saudi Arabia: lessons from a major trauma registry in Riyadh, Saudi Arabia.

    abstract:BACKGROUND AND OBJECTIVES:In Saudi Arabia (SA), injuries are the second leading cause of death; however, little is known about their frequencies and outcomes. Trauma registries play a major role in measuring the burden on population health. This study aims to describe the population of the only hospital-based trauma re...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2014.291

    authors: Alghnam S,Alkelya M,Al-Bedah K,Al-Enazi S

    更新日期:2014-07-01 00:00:00

  • Cochlear implant and thiamine-responsive megaloblastic anemia syndrome.

    abstract::Thiamine-responsive megaloblastic anemia syndrome is a rare autosomal recessive disorder defined by the occurrence of megaloblastic anemia, diabetes mellitus, and bilateral sensorineural deafness, responding in varying degrees to thiamine treatment. We report a precedence case for the treatment of deafness associated ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2014.78

    authors: Hagr AA

    更新日期:2014-01-01 00:00:00

  • Geographical distribution of congenital heart defects in Saudi Arabia.

    abstract:BACKGROUND:Congenital heart defects (CHD), which are caused by abnormalities early in fetal life, encompass over 50 diagnoses. Since the detailed etiology is unknown, the geographical distribution of defects might suggest likely risk factors. METHODS:The geographical distribution of 5 865 Saudi Arabian nationals with ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2005.63

    authors: Greer W,Sandridge AL,Al-Menieir M,Al Rowais A

    更新日期:2005-01-01 00:00:00

  • Accuracy of acetaminophen dosing in children by caregivers in Saudi Arabia.

    abstract:BACKGROUND AND OBJECTIVES:Fever contributes to a significant number of visits by children to the emergency department (ED), where it is often treated with acetaminophen. The objective of this study was to determine if caregivers give children with fever an accurate dose of acetaminophen and determine factors associated...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.4103/0256-4947.84630

    authors: Alomar M,Alenazi F,Alruwaili N

    更新日期:2011-09-01 00:00:00

  • Trihexyphenidyl (artane) abuse among Saudi psychiatric patients.

    abstract::This preliminary study done by abstracting relevant data from different testing material and using multiple rating scales, describes the sociodemographic variables, psychopathological correlates, and features of trihexyphenidyl (artane) abuse in a sample of 14 Saudi psychiatric patients and, as a result of this resear...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1992.391

    authors: Qureshi NA

    更新日期:1992-07-01 00:00:00

  • Cerebrospinal fluid leakage after turbinate submucosal diathermy: an unusual complication.

    abstract::Submucosal diathermy of the inferior turbinate (SMDIT) is a generally safe procedure to control inferior turbinate hypertrophy. We present a case of a cerebrospinal fluid (CSF) leak at the craniocervical junction after SMDIT done in another institution. A 27-year-old man presented 3 weeks after undergoing SMDIT with s...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2018.143

    authors: Abobotain AH,Ajlan A,Alsaleh S

    更新日期:2018-03-01 00:00:00

  • Follicular thyroid carcinoma within a thyroglossal duct cyst in adult.

    abstract::Thyroglossal duct cyst carcinoma is a rare malignancy, with an incidence of 0.7% to 1.6%. Most cases of thyroglossal duct cyst carcinoma are papillary carcinoma, with follicular carcinoma having been rarely reported. In this study, a 33-year-old man presented with a typical thyroglossal duct cyst and underwent surgica...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2018.305

    authors: Bifari IN,Alherabi A,Alkaff H,Al-Arqen H,Jastania RA

    更新日期:2018-07-01 00:00:00

  • Life-saving percutaneous intervention in young patient with massive pulmonary embolism.

    abstract::Massive pulmonary embolism (PE) is not an uncommon condition, and it usually carries a high risk of mortality. It is one of the fatal conditions that commonly affect young patients. A definitive treatment for patients with massive PE is still lacking, and surgical intervention carries a substantial mortality risk. Thu...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2012.433

    authors: Yaakob ZH,Undok AW,Abidin IZ,Wan Ahmad WA

    更新日期:2012-07-01 00:00:00

  • Neural tube defects in Southwestern region of Saudi Arabia.

    abstract::During December 1987 to December 1990 the incidence of neural tube defects in the Asir region located in southwestern Saudi Arabia was 0.82/1000. These results were drawn from a survey conducted of all cases of neural tube defects referred to the main hospital at Abha City (Asir Central Hospital) (ACH). Anencephaly wa...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1992.449

    authors: El-Awad Mel-H,Sivasankaran S

    更新日期:1992-09-01 00:00:00

  • Adult acute myeloblastic leukemia: Experience at King Khalid University Hospital.

    abstract:BACKGROUND:The clinical features of acute myeloblastic leukemia (AML) and its response to therapy in adult patients in Saudi Arabia are not well defined, as only scanty data has been available. This situation will likely continue unless experience with AML is reported from different institutions in the Kingdom. PATIEN...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1998.221

    authors: Harakati MS,Al-Momen AM,Ajarim DS,Al-Moharib FI,Al-Theyab A,Fawzy EM,Al-Gwaiz L,Al-Khairy KS

    更新日期:1998-05-01 00:00:00

  • Genotyping of rifampin-resistant Mycobacterium tuberculosis isolates from western Turkey.

    abstract:BACKGROUND:Although the rate of multiple drug resistance is high, there is no published data on the transmission rate of drug-resistant strains of Mycobacterium tuberculosis in the Aegean region of western Turkey that are based on molecular methods. METHODS:IS6110 and pTBN12 restriction fragment length polymorphism (R...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2004.102

    authors: Cavusoglu C,Durmaz R,Bilgic A,Gunal S

    更新日期:2004-03-01 00:00:00

  • Myxopapillary ependymoma masquerading as subcutaneous sacrococcygeal non-healing ulcer: case report.

    abstract::Ependymomas outside the confines of the cranium and spinal cord are rare. The occurrence of these tumors in an extradural, sacrococcygeal, or subcutaneous location may prove challenging, particularly in the absence of any obvious central nervous system connection. The origin of these tumors from sub.cutaneous sacrococ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2014.262

    authors: Zaidi SN,AlKhalidi H,Al-Rikabi AC

    更新日期:2014-05-01 00:00:00

  • Saudi Heart Rhythm Society Task Force on Management of Potential Arrhythmogenicity Associated with Pharmacotherapy for COVID-19.

    abstract::Evidence of cardiovascular complications associated with the COVID-19 global pandemic continues to evolve. These include direct and indirect myocardial injury with subsequent acute myocardial ischemia, and cardiac arrhythmia. Some results from a limited number of trials of antiviral medications, along with chloroquine...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,评审

    doi:10.5144/0256-4947.2020.365

    authors: AlShoaibi NA,Maghrabi K,Alanazi H,Harbi MA,Alghamdi S

    更新日期:2020-09-01 00:00:00

  • Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt.

    abstract:BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause a spectrum of hemolytic manifestations. OBJECTIVE:To determine the local prevalence of G6PD deficiency in newborns. DESIGN:Cross-sectional. SETT...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2017.362

    authors: Elella SA,Tawfik M,Barseem N,Moustafa W

    更新日期:2017-09-01 00:00:00

  • Benign disorders of the prostate: A histopathological study.

    abstract::Although the medical literature contains adequate accounts of the pathophysiology of various benign prostatic disorders, it is often necessary to revisit these lesions, to reexamine the relationships between known benign lesions and more sinister, malignant disorders, in the light of new advances in our understanding ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1998.22

    authors: Anim JT,Ebrahim BH,Sathar SA

    更新日期:1998-01-01 00:00:00

  • Endobronchial valve vs coil for lung volume reduction in emphysema: results from a tertiary care centre in Turkey.

    abstract:BACKGROUND:Bronchoscopic lung volume reduction (BLVR) by either the endobronchial valve (EBV) or coil (EBC) procedure is recommended for severe emphysematous patients. BLVR applications generally help healthy lung areas ventilate more comfortably by reducing the hyperinflation and improving the contraction capacity of ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2020.469

    authors: Dumanli A,Metin B,Gunay E

    更新日期:2020-11-01 00:00:00

  • Fine-needle aspiration biopsy diagnosis of pediatric neoplasms.

    abstract::A series of fine-needle aspiration biopsies performed in 635 children were reviewed. The diagnosis rendered in these patients included malignant lymphoma in 139 (21.9%), Hodgkin's disease, 25 (3.9%); neuroblastoma, 58 (9.1%); Wilms' tumor, 37 (5.8%); Ewing's sarcoma, 32 (5.0%); rhabdomyosarcoma, 25 (3.9%); retinoblast...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1991.366

    authors: Akhtar M,Ali MA,Burgess A,Huq M,Bakry M

    更新日期:1991-07-01 00:00:00

  • Epidemiology of sickle cell disease in Saudi Arabia.

    abstract::Sickle cell disease (SCD) is an autosomal recessive disorder characterized by production of abnormal hemoglobin S and is associated with high morbidity and mortality. Information about the prevalence of SCD in Saudi Arabia is patchy and probably underestimated, but studies have reported that SCD is a relatively common...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,评审

    doi:10.4103/0256-4947.81540

    authors: Jastaniah W

    更新日期:2011-05-01 00:00:00

  • Antibiotic prescribing patterns for sore throat infections in a university-based primary care clinic.

    abstract:BACKGROUND:Recent studies reveal that a high percentage (over 50%) of episodes for upper respiratory tract infections (URTIs) are treated with antibiotics, regardless of appropriateness or the necessity for prescription. We identified antibiotic prescriptions in a primary health care centre (PHC) and evaluated their su...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2005.22

    authors: Ayranci U,Akgün Y,Unluoglu I,Kiremitci A

    更新日期:2005-01-01 00:00:00

  • The changing face of healthcare in Saudi Arabia.

    abstract::Many countries now struggle to provide cost-effective, quality healthcare services to their citizens. Saudi Arabia has experienced high costs along with concerns about quality of care in its public facilities. To address these issues the country is currently restructuring their healthcare system to privatize public ho...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2008.243

    authors: Walston S,Al-Harbi Y,Al-Omar B

    更新日期:2008-07-01 00:00:00

  • Grading of follicular lymphoma using flow cytometry.

    abstract:BACKGROUND:The treatment and prognosis of follicular lymphoma (FL) is dependant on the grade of the disease. In the World Health Organization classification of lymphoma, grading of FL into low grade (1 and 2) and high grade (3) is recommended. Grading of FL is possible in excision biopsy; histological grading is subjec...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2006.205

    authors: Mourad WA,Rawas F,Shoukri M,Tbakhi A,Al Omari M,Tulbah A,Al Dayel F

    更新日期:2006-05-01 00:00:00

  • Zinc and antioxidant vitamin deficiency in patients with severe sickle cell anemia.

    abstract:BACKGROUND:Patients with severe sickle cell anemia (SCA) have a higher potential for oxidative damage due to chronic redox imbalance in red blood cells that often leads to hemolysis, endothelial injury and recurrent vaso-occlusive episodes. This study evaluated the plasma levels of vitamins A, C and E as indicators of ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2006.17

    authors: Hasanato RM

    更新日期:2006-01-01 00:00:00

  • Outcome after ileal pouch-anal anastomosis for familial adenomatous polyposis compared to mucosal ulcerative colitis in a Middle Eastern population.

    abstract:BACKGROUND AND OBJECTIVES:To compare the complications and outcome after ileal pouch-anal anastomosis (IPAA) for mucosal ulcerative colitis (MUC) and familial adenomatous polyposis (FAP). DESIGN AND SETTINGS:This is a retrospective study. The study was conducted at a single tertiary referral center. METHODS:All patie...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2013.268

    authors: Al-Sanea N,Alfaifi J,Homoud SA,Abduljabbar A,Hibbert D,Ashari L

    更新日期:2013-05-01 00:00:00

  • Fiberoptic, conventional and combination phototherapy for treatment of nonhemolytic hyperbilirubinemia in neonates.

    abstract::The objective of this prospective, randomized study was to compare the effectiveness of fiberoptic, conventional and a combination phototherapy in decreasing bilirubin concentrations in neonatal nonhemolytic hyperbilirubinemia. Forty-six infants who were 36 weeks' gestation and more were randomly assigned to fiberopti...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1996.633

    authors: Al-Alaiyan S

    更新日期:1996-11-01 00:00:00

  • Clinicopathological study of male breast carcinoma: 24 years of experience.

    abstract:BACKGROUND AND OBJECTIVES:Because breast cancer in men is rare, few patients are available for prospective studies. To learn more about its epidemiology, risk factors, clinical features, genetics and pathology in our country, we conducted a retrospective study of all cases seen in recent decades at our institution. PA...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.4103/0256-4947.55314

    authors: Shah P,Robbani I,Shah O

    更新日期:2009-07-01 00:00:00

  • Leukemia in the eastern region of Saudi Arabia: A population-based study (1987-1988).

    abstract::This is the first population-based data in Saudi Arabia on the incidence of leukemias in the Eastern Region, as conducted by its regional tumor registry. Data on cancer were captured from all health facilities in the region in 1987-1988. Population census was derived from a survey. Data on cancer deaths were obtained ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1996.521

    authors: Al-Bar AA,Ibrahim EM,Al-Tamimi TM,Assuhaimi SA,Ibrahim AW,Gabriel GS,Mishriky AM

    更新日期:1996-09-01 00:00:00

  • Cutaneous T-cell lymphoma in Saudi Arabia: retrospective single-center review.

    abstract:BACKGROUND:Cutaneous T-cell lymphoma (CTCL) is an uncommon disease with various clinical presentations. The hypopigmented type is more common in individuals with a dark skin complexion. Moreover, childhood CTCL is more common in Mediterranean populations in comparison to the West. OBJECTIVE:To describe CTCL in the Sau...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2017.212

    authors: Binamer Y

    更新日期:2017-05-01 00:00:00

  • Designing an autoverification system in Zagazig University Hospitals Laboratories: preliminary evaluation on thyroid function profile.

    abstract:BACKGROUND AND OBJECTIVES:The current practice in Zagazig University Hospitals Laboratories (ZUHL) is manual verification of all results for the later release of reports. These processes are time consuming and tedious, with large inter-individual variation that slows the turnaround time (TAT). Autoverification is the p...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2014.427

    authors: Sediq AM,Abdel-Azeez AG

    更新日期:2014-09-01 00:00:00