Acute kidney injury in the tropics.

Abstract:

:Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and poor areas in the tropics. The true epidemiological picture of AKI in the tropics is not well understood due to the late presentation of patients to tertiary centers. Infections remain the major culprit in most cases of AKI, with high mortality rates in the tropics. Human immunodeficiency virus-related AKI, related to nephrotoxicity due to antiretroviral therapy, is on the rise. Acute tubular necrosis and thrombotic microangiopathy are the most common mechanisms of AKI. A notable problem in the tropics is the scarcity of resources in health centers to support patients who require critical care due to AKI. This article reviews the unique and contrasting nature of AKI in the tropics and describes its management in each situation.

journal_name

Ann Saudi Med

journal_title

Annals of Saudi medicine

authors

Mathew AJ,George J

doi

10.4103/0256-4947.84620

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

451-6

issue

5

eissn

0256-4947

issn

0975-4466

pii

AnnSaudiMed_2011_31_5_451_84620

journal_volume

31

pub_type

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