On-line biomass measurements in bioreactor cultivations: comparison study of two on-line probes.


:Two on-line probes for biomass measurement in bioreactor cultivations were evaluated. One probe is based on near infrared (NIR) light absorption and the other on dielectric spectroscopy. The probes were used to monitor biomass production in cultivations of several different microorganisms. Differences in NIR probe response compared to off-line measurement methods revealed that the most significant factor affecting the response was cell shape. The NIR light absorption method is more developed and reliable for on-line in situ biomass estimation than dielectric spectroscopy. The NIR light absorption method is, however, of no significant use, when the cultivation medium is not clear, and especially in processes using adsorbents or solid matrix for the microorganism to grow on. The possibilities offered by dielectric spectroscopy are impressive, but the on-line probe technology needs to be


Kiviharju K,Salonen K,Moilanen U,Meskanen E,Leisola M,Eerikäinen T




Has Abstract


2007-08-01 00:00:00












  • Yeast culture collections of the world: meeting the needs of industrial researchers.

    abstract::The importance of selecting optimal yeast strains for research or industrial applications is often underestimated. For example, utilizing a strain background that already provides the desired stress tolerance or nutrient utilization profile can eliminate costly strain optimization. Yeast culture collections can provid...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章,评审


    authors: Boundy-Mills K

    更新日期:2012-05-01 00:00:00

  • Synthesis of 4-nitrophenyl acetate using molecular sieve-immobilized lipase from Bacillus coagulans.

    abstract::Extracellular lipase from Bacillus coagulans BTS-3 was immobilized on (3 A x 1.5 mm) molecular sieve. The molecular sieve showed approximately 68.48% binding efficiency for lipase (specific activity 55 IU mg(-1)). The immobilized enzyme achieved approx 90% conversion of acetic acid and 4-nitrophenol (100 mM each) into...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Raghuvanshi S,Gupta R

    更新日期:2009-03-01 00:00:00

  • Nicotinic acid controls lactate production by K1-LDH: a Saccharomyces cerevisiae strain expressing a bacterial LDH gene.

    abstract::Industrial applications for lactate, such as the production of chemicals, has led to interest in producing this organic acid by metabolically engineered a yeast such as Saccharomyces cerevisiae, which is more acid tolerant than lactic acid bacteria. This paper deals with lactate production by S. cerevisiae K1-LDH, in ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Colombié S,Sablayrolles JM

    更新日期:2004-06-01 00:00:00

  • Enhanced thermostability of keratinase by computational design and empirical mutation.

    abstract::Keratinases are proteolytic enzymes capable of degrading insoluble keratins. The importance of these enzymes is being increasingly recognized in fields as diverse as animal feed production, textile processing, detergent formulation, leather manufacture, and medicine. To enhance the thermostability of Bacillus lichenif...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Liu B,Zhang J,Fang Z,Gu L,Liao X,Du G,Chen J

    更新日期:2013-07-01 00:00:00

  • Very high gravity (VHG) ethanolic brewing and fermentation: a research update.

    abstract::There have been numerous developments in ethanol fermentation technology since the beginning of the new millennium as ethanol has become an immediate viable alternative to fast-depleting crude reserves as well as increasing concerns over environmental pollution. Nowadays, although most research efforts are focused on ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章,评审


    authors: Puligundla P,Smogrovicova D,Obulam VS,Ko S

    更新日期:2011-09-01 00:00:00

  • Effect of growth substrate, method of fermentation, and nitrogen source on lignocellulose-degrading enzymes production by white-rot basidiomycetes.

    abstract::The exploration of seven physiologically different white rot fungi potential to produce cellulase, xylanase, laccase, and manganese peroxidase (MnP) showed that the enzyme yield and their ratio in enzyme preparations significantly depends on the fungus species, lignocellulosic growth substrate, and cultivation method....

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Elisashvili V,Kachlishvili E,Penninckx M

    更新日期:2008-11-01 00:00:00

  • Comparative analysis of oxygen transfer rate distribution in stirred bioreactor for simulated and real fermentation broths.

    abstract::Study of the distribution of the oxygen mass transfer coefficient, k (l) a, for a stirred bioreactor and simulated (pseudoplastic solutions of carboxymethylcellulose sodium salt) bacterial (P. shermanii), yeast (S. cerevisiae), and fungal (P. chrysogenum free mycelia) broths indicated significant variation of transfer...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Caşcaval D,Galaction AI,Turnea M

    更新日期:2011-09-01 00:00:00

  • Engineering Yarrowia lipolytica for the production of cyclopropanated fatty acids.

    abstract::Traditional synthesis of biodiesel competes with food sources and has limitations with storage, particularly due to limited oxidative stability. Microbial synthesis of lipids provides a platform to produce renewable fuel with improved properties from various renewable carbon sources. Specifically, biodiesel properties...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Markham KA,Alper HS

    更新日期:2018-10-01 00:00:00

  • Expression of tylM genes during tylosin production: phantom promoters and enigmatic translational coupling motifs.

    abstract::In the genome of Streptomyces fradiae, the three tylM genes are codirectional with the upstream gene, tylGV. Although the introduction of transcriptional blocks into the tylM genes revealed that they are normally cotranscribed, expression of tylMI still persisted (albeit at a very low level) when either of the upstrea...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Flint SA,Stratigopoulos G,Butler AR,Cundliffe E

    更新日期:2002-03-01 00:00:00

  • Isolation and characterization of endophytic huperzine A-producing fungi from Huperzia serrata.

    abstract::Huperzia serrata is a producer of huperzine A (HupA), a cholinesterase inhibitor (ChEI). Over 120 endophytic fungi were recovered from this plant and screened for Hup-A and nine were found. These nine represented seven different fungal genera with the most significant producer being Shiraia sp. A total of 127 endophyt...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Wang Y,Zeng QG,Zhang ZB,Yan RM,Wang LY,Zhu D

    更新日期:2011-09-01 00:00:00

  • Cloning and characterization of a thermostable superoxide dismutase from the thermophilic bacterium Rhodothermus sp. XMH10.

    abstract::A superoxide dismutase (SOD) gene was cloned from the thermophilic bacterium Rhodothermus sp. XMH10 for the first time and highly expressed in Escherichia coli. The Rhodothermus sp. XMH10 SOD (RhSOD) gene encodes 209 amino acids with a putative molecular weight of 23.6 kDa and a pI value of 5.53. The recombinant RhSOD...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Wang X,Yang H,Ruan L,Liu X,Li F,Xu X

    更新日期:2008-02-01 00:00:00

  • Microaerophilic alkane degradation in Pseudomonas extremaustralis: a transcriptomic and physiological approach.

    abstract::Diesel fuel is one of the most important sources of hydrocarbon contamination worldwide. Its composition consists of a complex mixture of n-alkanes, branched alkanes and aromatic compounds. Hydrocarbon degradation in Pseudomonas species has been mostly studied under aerobic conditions; however, a dynamic spectrum of o...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Tribelli PM,Rossi L,Ricardi MM,Gomez-Lozano M,Molin S,Raiger Iustman LJ,Lopez NI

    更新日期:2018-01-01 00:00:00

  • Identification and characterization of a novel cold-adapted esterase from a metagenomic library of mountain soil.

    abstract::A novel lipolytic enzyme was isolated from a metagenomic library after demonstration of lipolytic activity on an LB agar plate containing 1% (w/v) tributyrin. A novel esterase gene (estIM1), encoding a lipolytic enzyme (EstIM1), was cloned using a shotgun method from a pFosEstIM1 clone of the metagenomic library, and ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Ko KC,Rim SO,Han Y,Shin BS,Kim GJ,Choi JH,Song JJ

    更新日期:2012-05-01 00:00:00

  • Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes.

    abstract::Nucleoside antibiotics constitute an important family of microbial natural products bearing diverse bioactivities and unusual structural features. Their biosynthetic logics are unique with involvement of complex multi-enzymatic reactions leading to the intricate molecules from simple building blocks. Understanding how...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章,评审


    authors: Chen W,Qi J,Wu P,Wan D,Liu J,Feng X,Deng Z

    更新日期:2016-03-01 00:00:00

  • A simulation study comparing the impact of experimental error on the performance of experimental designs and artificial neural networks used for process screening.

    abstract::Many variables and their interactions can affect a biotechnological process. Testing a large number of variables and all their possible interactions is a cumbersome task and its cost can be prohibitive. Several screening strategies, with a relatively low number of experiments, can be used to find which variables have ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Soria MA,Gonzalez Funes JL,Garcia AF

    更新日期:2004-11-01 00:00:00

  • Adaptation of the xylose fermenting yeast Saccharomyces cerevisiae F12 for improving ethanol production in different fed-batch SSF processes.

    abstract::An efficient fermenting microorganism for bioethanol production from lignocellulose is highly tolerant to the inhibitors released during pretreatment and is able to ferment efficiently both glucose and xylose. In this study, directed evolution was employed to improve the xylose fermenting Saccharomyces cerevisiae F12 ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Tomás-Pejó E,Ballesteros M,Oliva JM,Olsson L

    更新日期:2010-11-01 00:00:00

  • Flux to acetate and lactate excretions in industrial fermentations: physiological and biochemical implications.

    abstract::The efficiency of carbon conversion to biomass and desirable end products in industrial fermentations is diminished by the diversion of carbon to acetate and lactate excretions. In this study, the use of prototrophic and mutant strains of Escherichia coli, as well as enzyme active site directed inhibitors, revealed th...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: El-Mansi M

    更新日期:2004-08-01 00:00:00

  • Identification of bacteria contaminating pulp and a paper machine in a Canadian paper mill.

    abstract::Over 100 bacteria from pulp and slime samples in a Canadian paper mill were identified by partial sequencing of their 16S rDNAs. Seventy-one percent of the isolates could be assigned to a bacterial genus with a high level of confidence. Another 12% exhibited at least 95% similarity within their 16S rDNA sequence with ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Desjardins E,Beaulieu C

    更新日期:2003-03-01 00:00:00

  • Scalable economic extracellular synthesis of CdS nanostructured particles by a non-pathogenic thermophile.

    abstract::We report microbially facilitated synthesis of cadmium sulfide (CdS) nanostructured particles (NP) using anaerobic, metal-reducing Thermoanaerobacter sp. The extracellular CdS crystallites were <10 nm in size with yields of ~3 g/L of growth medium/month with demonstrated reproducibility and scalability up to 24 L. Dur...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Moon JW,Ivanov IN,Duty CE,Love LJ,Rondinone AJ,Wang W,Li YL,Madden AS,Mosher JJ,Hu MZ,Suresh AK,Rawn CJ,Jung H,Lauf RJ,Phelps TJ

    更新日期:2013-11-01 00:00:00

  • Accumulation of organic acids in cultivations of Neisseria meningitidis C.

    abstract::Aiming at the industrial production of serogroup C meningococcal vaccine, different experimental protocols were tested to cultivate Neisseria meningitidis C and to investigate the related organic acid release. Correlations were established between specific rates of acetic acid and lactic acid accumulation and specific...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Baruque-Ramos J,Hiss H,Converti A,Gonçalves VM,Raw I

    更新日期:2006-10-01 00:00:00

  • Comparative analysis of the Corynebacterium glutamicum transcriptome in response to changes in dissolved oxygen levels.

    abstract::The dissolved oxygen (DO) level of a culture of Corynebacterium glutamicum (C. glutamicum) in a bioreactor has a significant impact on the cellular redox potential and the distribution of energy and metabolites. In this study, to gain a deeper understanding of the effects of DO on the metabolism of C. glutamicum, we s...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章,收录出版


    authors: Liu X,Yang S,Wang F,Dai X,Yang Y,Bai Z

    更新日期:2017-02-01 00:00:00

  • Structural analysis of the curdlan-like exopolysaccharide produced by Cellulomonas flavigena KU.

    abstract::Cellulomonas flavigena KU produces large quantities of an insoluble exopolysaccharide (EPS) under certain growth conditions. The EPS has previously been shown to be a glucose polymer and to have solubility properties similar to curdlan, a beta-1,3-D-glucan produced by Alcaligenes faecalis var. myxogenes 10C3K. Further...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Kenyon WJ,Buller CS

    更新日期:2002-10-01 00:00:00

  • Cutinase production by Fusarium oxysporum in liquid medium using central composite design.

    abstract::The objective of the present study was to measure the production of cutinase by Fusarium oxysporum in the presence of several carbon and nitrogen sources (glycides, fatty acids and oils, and several organic and inorganic nitrogen sources), trying to find a cost-effective substitute for cutin in the culture medium as a...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Pio TF,Macedo GA

    更新日期:2008-01-01 00:00:00

  • Transcriptome analysis of probiotic Lactobacillus casei Zhang during fermentation in soymilk.

    abstract::Lactobacillus casei Zhang is a widely recognized probiotic bacterium, which is being commercially used in China. To study the gene expression dynamics of L. casei Zhang during fermentation in soymilk, a whole genome microarray was used to screen for differentially expressed genes when grown to the lag phase, the late ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Wang JC,Zhang WY,Zhong Z,Wei AB,Bao QH,Zhang Y,Sun TS,Postnikoff A,Meng H,Zhang HP

    更新日期:2012-01-01 00:00:00

  • Functional expression of a single-chain antibody fragment against human epidermal growth factor receptor 2 (HER2) in Escherichia coli.

    abstract::The human epidermal growth factor receptor (HER) family plays an important role in cell growth and signaling and alteration of its function has been demonstrated in many different kinds of cancer. Receptor dimerization is necessary for the HER signal transduction pathway and tyrosine kinase activity. Recently, several...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Akbari V,Mir Mohammad Sadeghi H,Jafrian-Dehkordi A,Abedi D,Chou CP

    更新日期:2014-06-01 00:00:00

  • Production of bioethanol from organic whey using Kluyveromyces marxianus.

    abstract::Ethanol production by K. marxianus in whey from organic cheese production was examined in batch and continuous mode. The results showed that no pasteurization or freezing of the whey was necessary and that K. marxianus was able to compete with the lactic acid bacteria added during cheese production. The results also s...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Christensen AD,Kádár Z,Oleskowicz-Popiel P,Thomsen MH

    更新日期:2011-02-01 00:00:00

  • Novel optimal temperature profile for acidification process of Lactobacillus bulgaricus and Streptococcus thermophilus in yoghurt fermentation using artificial neural network and genetic algorithm.

    abstract::The acidification behavior of Lactobacillus bulgaricus and Streptococcus thermophilus for yoghurt production was investigated along temperature profiles within the optimal window of 38-44 degrees C. For the optimal acidification temperature profile search, an optimization engine module built on a modular artificial ne...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Gueguim-Kana EB,Oloke JK,Lateef A,Zebaze-Kana MG

    更新日期:2007-07-01 00:00:00

  • Identification of oleaginous yeasts that metabolize aromatic compounds.

    abstract::The valorization of lignin is critical for the economic viability of the bioeconomy. Microbial metabolism is advantageous for handling the myriad of aromatic compounds resulting from lignin chemical or enzymatic depolymerization. Coupling aromatic metabolism to fatty acid biosynthesis makes possible the production of ...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Yaguchi A,Franaszek N,O'Neill K,Lee S,Sitepu I,Boundy-Mills K,Blenner M

    更新日期:2020-10-01 00:00:00

  • High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actll-ORF4.

    abstract::Streptomyces lividans 1,326 usually does not produce the red/blue colored polyketide actinorhodin in liquid culture even though it carries the entire actinorhodin biosynthesis gene cluster. The bacterium can be forced to produce this secondary metabolite by introducing actII-ORF4, the actinorhodin pathway-specific act...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Bruheim P,Sletta H,Bibb MJ,White J,Levine DW

    更新日期:2002-02-01 00:00:00

  • Production of nisin Z using Lactococcus lactis IO-1 from hydrolyzed sago starch.

    abstract::A membrane bioreactor for production of nisin Z was constructed using Lactococcus lactis IO-1 in continuous culture using hydrolyzed sago starch as carbon source. A strategy used to enhance the productivity of nisin Z was to maintain the cells in a continuous growth at high cell concentration. This resulted in a volum...

    journal_title:Journal of industrial microbiology & biotechnology

    pub_type: 杂志文章


    authors: Carvajal-Zarrabal O,Nolasco-Hipólito C,Bujang KB,Ishizaki A

    更新日期:2009-03-01 00:00:00