Genetically determined mannan-binding lectin deficiency is of minor importance in determining susceptibility to severe infections and vascular organ damage in systemic lupus erythematosus.

abstract：:Intestinal pseudo-obstruction (IpsO) occurs in a small subgroup of patients with systemic lupus erythematosus (SLE), and has been under-recognized. The etiology and mechanisms are unclear. Herein, we report two cases. In case 1, IpsO occurred as the complication in a previously diagnosed SLE patient. In case 2, IpsO w...

journal_title：Lupus

authors： Zhang J,Fang M,Wang Y,Mao J,Sun X

更新日期：2011-10-01 00:00:00

abstract：:Female B6.MRLc1(82-100) congenic mice develop more severe autoimmune glomerulonephritis (AGN) than males. We assessed the effects of gonadectomy on the pathogenesis of AGN in these mice. One-month-old male and female mice were divided into sham-operated group (SG) and gonadectomized group (GG), and the pathological ch...

journal_title：Lupus

authors： Ichii O,Konno A,Sasaki N,Endoh D,Hashimoto Y,Kon Y

更新日期：2009-05-01 00:00:00

abstract：:Background and objective African-Americans and Hispanic-Americans with lupus are the two most common minority groups who receive kidney transplants in the USA. It is unknown if African-Americans and Hispanic-Americans with lupus have similar outcomes after kidney transplantation. In this study, we assessed whether Afr...

journal_title：Lupus

authors： Gonzalez-Suarez ML,Contreras G

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Fatigue in systemic lupus erythematosus (SLE) is burdensome and must be assessed using validated scales. Although the psychometric properties of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) scale in SLE have been evaluated previously, its content validity in this disease remain...

journal_title：Lupus

authors： Kosinski M,Gajria K,Fernandes AW,Cella D

更新日期：2013-04-01 00:00:00

abstract：:'Antiphospholipid' (aPL) antibodies are of clinical importance because of their strong association with vascular thrombosis, recurrent pregnancy loss, thrombocytopenia and other clinical manifestations like livedo reticularis, chorea and cardiac valvular disease. While aPL antibodies have traditionally been thought to...

journal_title：Lupus

authors： Kandiah DA,Krilis SA

更新日期：1996-04-01 00:00:00

abstract：INTRODUCTION:Several studies have shown that Hispanic patients generally experience a worse renal prognosis than non-Hispanic white patients with lupus. To date, there is no report on American College of Rheumatology (ACR) renal response criteria (ACR-RRC) in patients from Latin America. OBJECTIVE:To evaluate treatmen...

journal_title：Lupus

authors： Vinicki JP,Paniego FM,De Rosa G,Dubinsky D,Laborde HA,Marini A,Nasswetter G

更新日期：2016-02-01 00:00:00

abstract：:Autoantibodies against prothrombin, including lupus anticoagulant antibodies (LAC), have been identified in patients with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). To identify the epitopes of LAC in patients with SLE and APS, we analyzed B cell epitopes of anti-prothrombin Abs. Prothrombi...

journal_title：Lupus

authors： Akimoto T,Akama T,Kono I,Sumida T

更新日期：1999-01-01 00:00:00

abstract：:Legionnaire's disease (LD) is most commonly caused by Legionella pneumophila (L. pneumophila). In immunocompromised patients LD can cause necrosis of the lung parenchyma with abscess formation and cavitation. Systemic lupus erythematosus (SLE) is an autoimmune disorder with features of both primary and secondary immun...

journal_title：Lupus

authors： Khokher W,Kesireddy N,Adunse J,Mudiyanselage PH,Iftikhar S,Assaly R

更新日期：2021-01-26 00:00:00

abstract：:This manuscript discusses our studies to date concerning the effects of unmodified prolactin (PRL) and phosphorylated PRL on immune function. Most of the discussion refers to effects of changing the ratio of these two forms in maternal PRL on gamma delta T cell development in rat pups in utero, but limited experiments...

journal_title：Lupus

authors： Walker AM

更新日期：2001-01-01 00:00:00

abstract：:Structural and metabolic abnormalities in the hippocampus have been associated with the pathophysiological mechanism of central nervous system involvement in primary Sjögren syndrome (pSS). Nevertheless, how hippocampal function is altered in pSS remains unknown. The purpose of our study is to investigate the alterati...

journal_title：Lupus

authors： Zhang XD,Zhao LR,Zhou JM,Su YY,Ke J,Cheng Y,Li JL,Shen W

更新日期：2020-04-01 00:00:00

abstract：:Choroidal involvement in systemic lupus erythematosus (SLE) occurs infrequently. We report a 45-y-old woman with bilateral chorioretinopathy associated with SLE. Diagnosis was performed using indirect ophthalmoscopy, retinal fluorescein angiography (FA) and green indocianin angiography (ICG). In this patient chorioret...

journal_title：Lupus

authors： Paroli MP,Riso D,Pinca M,Pivetti-Pezzi P

更新日期：2001-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is characterized by the finding of ample serum autoantibodies. The role and the origin of many of these antibodies are still obscure. The aim of this work was to study the occurrence of anti-insulin antibodies (AIA) in SLE, and to postulate, based on AIA determination, on the mechani...

journal_title：Lupus

authors： Lidar M,Braf A,Givol N,Langevitz P,Pauzner R,Many A,Livneh A

更新日期：2001-01-01 00:00:00

abstract：:In prospective studies, increased levels of cardiolipin-biding antibodies and autoantibodies to oxidized low-density lipoprotein (LDL) have been observed in patients with myocardial infarction (MI). These findings suggest that antiphospholipid antibodies may contribute to the development of MI. The 'oxidative-modifica...

journal_title：Lupus

authors： Vaarala O

更新日期：1998-01-01 00:00:00

abstract：:Although a few reports in recent years have suggested that patients with antiphospholipid antibodies (aPL) are prone to developing primary anetoderma (PA), it is still unclear how often aPL are detected in unselected PA patients. We studied nine consecutive PA patients for the presence of autoimmune antibodies and dis...

journal_title：Lupus

authors： Hodak E,Feuerman H,Molad Y,Monselise Y,David M

更新日期：2003-01-01 00:00:00

abstract：:This study was conducted to determine kidney transplantation (KTx) outcomes for Greek patients with renal failure caused by lupus nephritis (LN) compared with matched controls, kidney recipients with other causes of end-stage renal disease (ESRD). Twenty-six patients with systemic lupus erythematosus (SLE) subjected t...

journal_title：Lupus

authors： Lionaki S,Kapitsinou PP,Iniotaki A,Kostakis A,Moutsopoulos HM,Boletis JN

更新日期：2008-07-01 00:00:00

abstract：:The presence of antibodies against the complex of prothrombin and phosphatidylserine (aPS/PT) more significantly correlates with manifestations of antiphospholipid syndrome (APS) and with the presence of lupus anticoagulants (LA) than antibodies against prothrombin bound to oxygenated polystyrene (aPT-A). To investiga...

journal_title：Lupus

authors： Horita T,Ichikawa K,Kataoka H,Yasuda S,Atsumi T,Koike T

更新日期：2007-01-01 00:00:00

abstract：:Our objective was to investigate whether quality of life in systemic lupus erythematosus (SLE) differs across ethnoracial groups and to identify factors that may explain race-related differences. Self-administered questionnaire data from 335 White, 40 Black, and 30 Asian women with SLE were obtained from a multi-cente...

journal_title：Lupus

authors： Devins GM,Edworthy SM

更新日期：2000-01-01 00:00:00

abstract：:Fatigue is one of the most complex and ill understood symptoms of chronic illness often reported as the number one complaint by patients with systemic lupus erythematosus (SLE). This paper aims to provide a comprehensive review of the literature on fatigue in SLE. A pool of 55 relevant articles was retrieved via elect...

journal_title：Lupus

authors： Cleanthous S,Tyagi M,Isenberg DA,Newman SP

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:Health-related quality of life (HRQoL) has not been fully explored in antiphospholipid syndrome (APS); therefore, we compared HRQoL between APS patients and the general population and assessed the impact of thromboembolic history. METHODS:HRQoL was measured in a multicentre cohort study by the Medical Outco...

journal_title：Lupus

authors： Zuily S,Rat AC,Regnault V,Kaminsky P,Mismetti P,Ninet J,Baillet N,Magy-Bertrand N,Pasquali JL,Lambert M,Pasquier E,Lorcerie B,Lecompte T,Guillemin F,Wahl D,TAC(I)T investigators.

更新日期：2015-10-01 00:00:00

abstract：:We describe a patient with rheumatoid arthritis (RA) whose sera contained a high titre of an antibody targeting cytoplasmic ribosomal P proteins (anti-P). This association preceded by 6 years the development of serological and clinical manifestations of systemic lupus erythematosus (SLE). The clinical significance of ...

journal_title：Lupus

authors： Hamasaki K,Mimura T,Kanda H,Morino N,Yazaki Y,Nojima Y

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To examine the immune cell profile in the bone marrow of systemic lupus erythematosus (SLE) patients and to assess its clinical relevance. METHODS:Sixteen bone marrow samples from 14 SLE patients were compared with seven healthy control samples. The numbers of immune cells and apoptotic cells in the bone ma...

journal_title：Lupus

authors： Park JW,Moon SY,Lee JH,Park JK,Lee DS,Jung KC,Song YW,Lee EB

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Anti-α-enolase antibody (Ab) combined with β2 microglobulin (β2-MG) were investigated to predict the incidence of nephritis in systemic lupus erythematosus (SLE) patients. METHODS:Levels of serum anti-α-enolase Ab and urinary β2-MG were detected in 115 SLE patients, 29 SLE patients with nephritis and 70 heal...

journal_title：Lupus

authors： Huang Y,Chen L,Chen K,Huang F,Feng Y,Xu Z,Wang W

更新日期：2019-03-01 00:00:00

abstract：:The objective of the study was to analyse the prevalence and clinical significance of hypocomplementemia in a large series of patients diagnosed either with systemic lupus erythematosus (SLE) or with primary antiphospholipid syndrome (APS) and its association with the main clinical, hematological and immunological fea...

journal_title：Lupus

authors： Ramos-Casals M,Campoamor MT,Chamorro A,Salvador G,Segura S,Botero JC,Yagüe J,Cervera R,Ingelmo M,Font J

更新日期：2004-01-01 00:00:00

abstract：:In 1964, Miyoshi reported a series of patients with diverse symptoms after receiving treatment with silicone or paraffin fillers. Miyoshi named this condition 'human adjuvant disease'. Since then, the literature has been flooded with case reports and case series of granulomatous and systemic autoimmune disorders relat...

journal_title：Lupus

authors： Alijotas-Reig J

更新日期：2015-09-01 00:00:00

abstract：:The aim of this study was to determine the frequency of anti-prolactin autoantibodies and the relationship among anti-prolactin autoantibodies, serum prolactin (PRL) levels and lupus activity in paediatric patients with systemic lupus erythematosus (SLE) using a transversal study. One-hundred and three consecutive pae...

journal_title：Lupus

authors： Blanco-Favela F,Quintal MaG,Chavez-Rueda AK,Leaños-Miranda A,Berron-Peres R,Baca-Ruiz V,Lavalle-Montalvo C

更新日期：2001-01-01 00:00:00

abstract：:To assess bladder function in systemic lupus erythematosus (SLE) patients with recurrent urinary tract infections (UTIs). A convenience sample of consecutive patients with SLE (American College of Rheumatology criteria), with recurrent UTIs (>/=3 events in the preceding 12 months), without history of central nervous s...

journal_title：Lupus

authors： Duran-Barragan S,Ruvalcaba-Naranjo H,Rodriguez-Gutierrez L,Solano-Moreno H,Hernandez-Rios G,Sanchez-Ortiz A,Ramos-Remus C

更新日期：2008-12-01 00:00:00

abstract：:A special interaction is established during pregnancy between the maternal immune system and fetal cells to allow the survival and the normal growth of the fetus. Fetal cells expressing paternal alloantigens are not recognized as foreign by the mother because of an efficient anatomic barrier and a local immunosuppress...

journal_title：Lupus

authors： Bulla R,Fischetti F,Bossi F,Tedesco F

更新日期：2004-01-01 00:00:00

abstract：:To study whether monoclonal anticardiolipin antibodies (aCL), derived from patients with antiphospholipid syndrome (APS), have similar pathogenic potential, we have employed an experimental model of antiphospholipid syndrome. Monoclonal aCL were produced by the combined method of EBV transformation and somatic cell hy...

journal_title：Lupus

authors： Bakimer R,Blank M,Kosashvilli D,Ichikawa K,Khamashta MA,Hughes GR,Koike T,Shoenfeld Y

更新日期：1995-06-01 00:00:00

abstract：:The objective of this study was to determine the HLA class II associations of the anticardiolipin (aCL) and anti-beta2GPI (abeta2GPI) antibodies in a large series of European patients with systemic lupus erythematosus (SLE). A cohort of 577 European SLE patients was enrolled. aCL and abeta2GPI were measured by ELISA m...

journal_title：Lupus

authors： Galeazzi M,Sebastiani GD,Tincani A,Piette JC,Allegri F,Morozzi G,Bellisai F,Scorza R,Ferrara GB,Carcassi C,Font J,Passiu G,Smolen J,Papasteriades C,Houssiau F,Nebro AF,Ramon Garrido ED,Jedryka-Goral A,Marcolongo R

更新日期：2000-01-01 00:00:00

abstract：:Associations of polymorphisms in vitamin D receptor (VDR) with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) have already been explored by many studies. The aim of this meta-analysis was to better clarify associations between polymorphisms in VDR and RA/SLE by combing the results of all relevant stu...

journal_title：Lupus

authors： Zhang WT,Jin TF,Chen L

更新日期：2020-04-01 00:00:00