Hyperprolactinemia and amenorrhea associated with olanzapine normalized after addition of aripiprazole.

abstract：OBJECTIVE:A large number of structurally and functionally diverse compounds act as substrates or modulators of p-glycoprotein (p-gp). Some of them possess multiple drug resistance (MDR)-reversing activity, but only a small number of them have entered clinical study. In order to uncover the factors which exert a signifi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Wang RB,Kuo CL,Lien LL,Lien EJ

更新日期：2003-06-01 00:00:00

abstract：:A population pharmacokinetic study was conducted on a total of 70 patients receiving gentamicin therapy. The patients included those with normal renal function and those with varying degrees of renal impairment. The parameters studied were the apparent volume of distribution and the plasma clearance of gentamicin. The...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lanao JM,Berrocal A,Calvo MV,Perez M,de la Calle B,Domínguez-Gil A

更新日期：1989-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Linezolid, a member of the oxazolidinone class of antibacterial drugs, is approved by the US Food and Drug Administration (FDA) for the treatment of vancomycin-resistant Enterococcus faecium infections, nosocomial and community-acquired pneumonia, as a part of anti tubercular regimen and com...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Singhania SVK,Shenoy S,Kapoor D

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Current guidelines recommend a combination of clopidogrel and aspirin for management of patients who have experienced an acute coronary syndrome (ACS). Additional antiplatelet agents have been recently approved. Few comparative effectiveness studies are available for these new agents. Accord...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Olson WH,Ma YW,Laliberté F,Lefebvre P,Crivera C,Schein JR,Fields LE,Dea K,Germain G,Lynch SM

更新日期：2014-12-01 00:00:00

abstract：:Midazolam concentration curves versus time were analysed in 10 otherwise healthy patients (ASA I-II) with inferior limb pathologies. The benzodiazepine was used as an adjuvant agent to epidural anaesthesia in view of its lower residual effect compared with other intravenous benzodiazepines. Midazolam pharmacokinetics...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sánchez-Alcaraz A,Sangrador G,Laguarda M,Quintana B

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of 500 mg ornidazole vaginal ovules (VO) and vaginal tablets (VT) in the treatment of bacterial vaginosis. METHOD:Patients were allocated at random to one group of 50 subjects to be treated with a VO (500 mg) prepared in our laboratory and to a second group of 50 subjects to be treate...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Baloğlu E,Ozyazici M,Baloğlu A,Ova L

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The anti-craving drug, naltrexone, is used as a pharmacotherapeutic adjunct in the treatment of alcohol dependence. In addictive disorders, compliance issues remain central. There are limited data on compliance with naltrexone treatment regimens within formalized rehabilitation programs and even less data th...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Feeney GF,Connor JP,Young RM,Tucker J,Czajkowski F

更新日期：2001-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:New first-in-class (FIC) drugs with novel mechanisms of action may be highly effective, but lack adequate safety information, and therefore may be associated with crucial post-marketing safety issues. The objective of this study was to evaluate the post-marketing risk of FIC drug with compar...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ikeda J,Kaneko M,Narukawa M

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Hyperthermia is an effective treatment modality that augments the anticancer effects of radiotherapy and chemotherapy. Hyperthermia-chemo-radiotherapy (HCRT) is a combination therapy that can strengthen anticancer effects through a synergistic interaction between heat, chemotherapy and radia...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hu Y,Li Z,Mi DH,Cao N,Zu SW,Wen ZZ,Yu XL,Qu Y

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:In paediatric pharmacotherapy, many drugs are prescribed to be given in ways and for conditions not approved in the marketing authorization (MA). Thus, off-label prescribing of drugs with no MA is widespread in paediatric wards. However, drug MA status and clinical practices differ across countries. In this ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lindell-Osuagwu L,Korhonen MJ,Saano S,Helin-Tanninen M,Naaranlahti T,Kokki H

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:The use of psychotropic drugs has increased continuously over recent years in industrialized countries. In Europe, France has the highest consumption of such drugs. The aim of this study was to identify the sociodemographic and medical factors associated with the use of psychotropic agents. METHODS:Data, co...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Empereur F,Baumann M,Alla F,Briançon S

更新日期：2003-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:Little is known about the ability of community pharmacists who are inexperienced in medication review to identify drug-related problems (DRPs). The objective of our study was to investigate the completeness of DRPs in terms of number, type and clinical relevance identified by community phar...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kwint HF,Faber A,Gussekloo J,Bouvy ML

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Morphine hydrochloride, a major analgesic drug, is being increasingly administered using portable disposable infusion devices. The objective of this study was to investigate the stability of morphine in such a system at two concentrations (2.50 and 5.00 mg/ ml) over a 30-day period. METHOD:Hig...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Oustric-Mendes AC,Huart B,Le Hoang MD,Perrin-Rosset M,Pailler FM,Darbord JC,Prognon P,Gard C,Pradeau D

更新日期：1997-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Terlipressin is widely used to treat variceal bleeding and hepatorenal syndrome. We report one case of stubborn hyponatraemia induced by long-term (up to 21 days) therapy with terlipressin and review the side effects of this agent. CASE SUMMARY:A 41-year-old man with variceal rebleeding exp...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Huang Y,Wang M,Wang J

更新日期：2015-12-01 00:00:00

abstract：:The efficacy of a novel, proprietary topical formulation of ibuprofen 5% gel (Ibugel) and ibuprofen 400 mg tablets (1200 mg daily) was compared in a double-blind, double-dummy, parallel group study in patients with acute soft tissue injuries. Patients received either active gel plus placebo tablets (n = 50) or active ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Whitefield M,O'Kane CJ,Anderson S

更新日期：2002-12-01 00:00:00

abstract：:Parenterals, sterile preparations intended to be injected in man or animal, should be free from pyrogenic substances which are able to raise the thermostatic setting in the hypothalamus. This article gives an up-to-date review of the principal detection and quantification methods for these agents, with special attenti...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Vanhaecke E,Pijck J,Vuye A

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Antiviral medications cost-effectively reduce influenza-related morbidity and potentially mortality. We sought to assess the appropriateness of antiviral prescribing for influenza. METHOD:We performed a retrospective analysis of visits by adults to primary care clinics during influenza seasons...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Linder JA,Chan JC,Bates DW

更新日期：2006-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Admixtures of levobupivacaine, fentanyl and epinephrine are increasingly used in epidural pain management. Neither the compatibility nor the stability of levobupivacaine with fentanyl and epinephrine is known and therefore we examined the chemical, physical and microbiological stability of l...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Helin-Tanninen M,Lehtonen M,Naaranlahti T,Venäläinen T,Pentikäinen J,Laatikainen A,Kokki H

更新日期：2013-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Although the risk of major bleeding with non-vitamin K antagonist oral anticoagulant (NOAC) is low, life-threatening bleeding can occur. CASE SUMMARY:We report a case of an 81-year-old female with deep vein thrombosis who developed bilateral spontaneous haemothorax and haemopericardium afte...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yu JH,Liu HH,Hsieh MJ,Hsieh IC,Chu PH,Chen DY

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To describe the current practice of Israeli paediatricians regarding acetaminophen dosing. METHODS:A cross-sectional survey among 200 paediatricians. The paediatricians were questioned of the recommended dose of acetaminophen, and whether they give prescriptions for acetaminophen and instruct their patients ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Greenberg R,Grossman Z,Goldstein L,Berkovitch M,Kozer E

更新日期：2005-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Serum sialic acid is a recently investigated potential risk-marker for cardiovascular complications. There is a known association between sialic acid and cardiovascular complications in diabetes mellitus. We aimed to investigate the effect of antidiabetic drugs on the serum concentration of ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Rahman IU,Malik SA,Bashir M,Khan RU,Idrees M

更新日期：2010-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Amlodipine overdose is common; however, the dose and timing of intravenous lipid emulsion (ILE) therapy as a management strategy remain debatable. CASE DESCRIPTION:A 73-year-old man received a single bolus (1.5 mL/kg) of ILE therapy following massive ingestion of multiple drugs, including a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ando M,Nakasako S,Ariyoshi K,Yamaguchi M,Sakizono K,Minowa K,Fukushima S,Sugioka N,Hashida T

更新日期：2019-12-01 00:00:00

abstract：:In many countries, including The Netherlands, little is known about the overall prescribing patterns within hospitals. While individual hospitals have some data available, these are not pooled on a regional or national level. The available data consist of dispensing data that are neither patient-linked nor diagnosis-l...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Denig P,Haaijer-Ruskamp FM,Versluis A,Wesseling H

更新日期：1991-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Psoriatic arthritis is an autoimmune disease characterized by chronic inflammation of the skin and joints. Anti-TNF drugs reduce the severity of the disease in the long term. This study compares the efficacy and safety of adalimumab, etanercept, infliximab and golimumab in patients with psor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fénix-Caballero S,Alegre-del Rey EJ,Castaño-Lara R,Puigventós-Latorre F,Borrero-Rubio JM,López-Vallejo JF

更新日期：2013-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The purpose of this study is to explore the clinical characteristics of tigecycline-induced acute pancreatitis. METHODS:We searched the PubMed/Medline, Web of Knowledge, OVID, Elsevier, Springer Link, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data, an...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fang W,Yi D,Sun L,Wang C

更新日期：2020-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:Thiopurines are cornerstone drugs in the treatment of acute lymphoblastic leukaemia (ALL), but their use can be complicated by the incidence of life-threatening leucopenia. CASE DESCRIPTION:We describe a case of a 6-year-old Chinese boy with B-ALL receiving extremely low dose of 6-mercapto...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhai XY,Zhou Y,Dong L,Nie AQ,Zhi LJ,Jacqz-Aigrain E,Wang TY,Wang L,Zhao W

更新日期：2021-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Aloe vera (Aloe vera (L.) Burm.f., Xanthorrhoeaceae family) has long been used in folk or traditional medicine for diabetes. Several studies have been conducted on the effect of Aloe vera on glycaemic control, but the results appear inconsistent. We undertook a systematic review and meta-ana...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suksomboon N,Poolsup N,Punthanitisarn S

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In early breast cancer patients the transformed epithelial cells are thought to be sensitive to transforming growth factor beta1 (TGFbeta1)-mediated growth arrest. TGFbeta1 may therefore act as an anti-tumour promoter. However, in advanced breast cancer resistance to such TGFbeta1 action develops. Neoplastic...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kajdaniuk D,Marek B,Swietochowska E,Ostrowska Z,Glogowska-Szelag J,Kos-Kudla B,Ciesielska-Kopacz N,Wielkoszyski T

更新日期：2000-08-01 00:00:00

abstract：AIM:Some studies have indicated that over-reliance on inhaled bronchodilator (beta 2-agonist) therapy may worsen asthma control and increase morbidity. The aim of this study was to measure urinary concentrations of salbutamol, the most commonly used bronchodilator, in a relatively large sample of asthmatic patients and...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Jacobson GA,Peterson GM,McLean S

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To assess the usefulness of dynamic laser scattering for monitoring the stability of ampicillin after reconstitution from commercially available vials with respect to the polymer formation and potency. METHODS:Polymer formation and the remaining potency of the reconstituted ampicillin solution were estimated...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sendo T,Teshima D,Makino K,Mishima K,Itoh Y,Oishi R

更新日期：2002-04-01 00:00:00