Analysis of clinical characteristics of tigecycline-induced acute pancreatitis.

abstract：WHAT IS KNOWN:The increased risk of cardiovascular events in diabetic patients has been related to numerous metabolic and haemoreological factors. Some of these factors appear to be particularly evident during the post-prandial phases and to be related to peak plasma glucose level. AIM:To compare the effect of additio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Derosa G,Mereu R,D'Angelo A,Salvadeo SA,Ferrari I,Fogari E,Gravina A,Palumbo I,Maffioli P,Randazzo S,Cicero AF

更新日期：2010-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chemotherapy can increase treatment-related mortality associated with future haematopoietic stem cell transplantation (HSCT) for patients with relapsed/refractory acute myeloid leukaemia (AML). There is usually insufficient time to find a suitable unrelated donor for these patients. We repor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhang C,Chen XH,Liu J,Gao L,Liu Y,Gao L,Kong PY,Zhang X

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To describe the current practice of Israeli paediatricians regarding acetaminophen dosing. METHODS:A cross-sectional survey among 200 paediatricians. The paediatricians were questioned of the recommended dose of acetaminophen, and whether they give prescriptions for acetaminophen and instruct their patients ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Greenberg R,Grossman Z,Goldstein L,Berkovitch M,Kozer E

更新日期：2005-10-01 00:00:00

abstract：:To dose the anticonvulsant phenytoin (PHT) in a clinical situation is difficult because of the non-linear metabolism of the drug. Therefore many techniques have been advocated to aid dosage adjustments based on a single-point PHT concentration determined at steady-state (ss). We retrospectively investigated six method...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yukawa E,Higuchi S,Ohtsubo K,Aoyama T

更新日期：1988-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Fluconazole is an antifungal agent that is commonly used to treat patients with serious systemic fungal infections in intensive care units. Fosfluconazole is a phosphate prodrug of fluconazole, which was developed to reduce the volume of fluid required to administer fluconazole by intravenou...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Aoyama T,Hirata K,Hirata R,Yamazaki H,Yamamoto Y,Hayashi H,Matsumoto Y

更新日期：2012-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Drug prescribing is an essential part of inpatient care, and prescription errors/omissions have the potential to lead to disastrous consequences. Paediatric inpatient prescribing is particularly sensitive to error due to the weight-adjusted dosing of many medications prescribed in the acute ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Bolt R,Yates JM,Mahon J,Bakri I

更新日期：2014-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The 4-factor prothrombin complex concentrate (4F-PCC) may be used to emergently achieve haemostasis in patients on anticoagulation prior to surgery. Limited data exist using the intraosseous route of administration of 4F-PCC in patients taking factor Xa inhibitors. CASE DESCRIPTION:We descr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ratliff P,Nutley K,Schroeder W,Cottingham L

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The HbA1C marker used in assessing diabetes control quality is not sufficient in diabetes patients with thalassaemia. CASE DESCRIPTION:A male diabetic patient with thalassaemia was hospitalized due to distal neuropathic pain, right toe trophic ulcer, unacceptable five-point glycaemic profil...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Gluvic Z,Obradovic M,Lackovic M,Samardzic V,Tica Jevtic J,Essack M,Bajic VB,Isenovic ER

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The application of population pharmacokinetics (PopPK) appears increasingly in drug labelling. The current study was to examine the use of PopPK in dose recommendation in drug-product labels. METHOD:PopPK information was identified in the data sheets included in the physician desk reference (P...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Duan JZ

更新日期：2007-02-01 00:00:00

abstract：:When assessing a health-care intervention the main question is--does it work? Often, a more difficult question needs to be answered--how well does it work? Systematic reviews and meta-analyses help to provide answers to both questions. Too often though, the results are expressed in a way that leaves the reader asking,...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Wiffen PJ,Moore RA

更新日期：1996-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone (ciclopirox) and specifically its olamine salt 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone 2-aminoethanol salt (ciclopirox olamine) are anti-fungal agents currently used for the treatment of mild to moderate cutaneous fungal infection. Our ob...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Weir SJ,Patton L,Castle K,Rajewski L,Kasper J,Schimmer AD

更新日期：2011-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Glucocorticoid-induced diabetes mellitus (GIDM) increases the risk of diabetes mellitus (DM)-related complications but is generally difficult to detect in clinical settings. The criteria for diagnosing GIDM have not been established. Recently, medical information databases (MIDs) have been u...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Imatoh T,Sai K,Hori K,Segawa K,Kawakami J,Kimura M,Saito Y

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The quality of 33 formulations of essential antimicrobial and antimalarial drugs (amoxicillin capsules, metronidazole tablets, sulfamethoxazole/trimethoprim tablets, quinine tablets and sulphadoxine/pyrimethamine tablets) marketed in Rwanda and Tanzania was assessed and the influence of tropical storage condi...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kayumba PC,Risha PG,Shewiyo D,Msami A,Masuki G,Ameye D,Vergote G,Ntawukuliryayo JD,Remon JP,Vervaet C

更新日期：2004-08-01 00:00:00

abstract：:Otitis media occurs commonly in children, and is usually treated with an antibiotic. In this case report, amoxicillin was prescribed for a 6-year-old boy suffering from acute otitis media. As he had previously experienced a rash after the administration of a penicillin, the medication order was switched from amoxicill...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Falconer CL,Gardner DM

更新日期：2000-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Low-dose methotrexate (LDMTX) has been widely used for many decades in clinical settings, with good safety profiles compared with those of high-dose methotrexate. LDMTX is also used as one of the off-label conservative therapies in treating placenta accreta (PA). Until now, only a few mild a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tan Z,Liu W,Guo H,Hu K,Zhao R

更新日期：2020-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:With increased opioid use, drug-drug interactions (DDIs) and associated adverse events are growing among geriatric patients. However, the clinical significance of potential metabolic DDIs associated with opioid use has not been fully evaluated among geriatric patients. Particularly, cytochro...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kim JH,Kim JY,Lee N,Yee J,Gwak HS

更新日期：2020-10-01 00:00:00

abstract：:Hyperprolactinemia is a frequent side-effect in the use of atypical antipsychotics. The propensity to induce hyperprolactinemia is highly substance dependent and hyperprolactinemia is not always associated with clinical side-effects. We report a case in which hyperprolactinemia and amenorrhea under the treatment with ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Wolf J,Fiedler U

更新日期：2007-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:In order to improve public health, it is necessary to facilitate patients' easy access to affordable high-quality primary health care, and one enhanced approach to do so may be to provide primary healthcare services in the community pharmacy setting. Discrete choice experiments to evaluate p...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Feehan M,Walsh M,Godin J,Sundwall D,Munger MA

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:There is evidence that patients are being prescribed potentially hazardous drug-drug combinations in general practice despite the use of computerized drug interaction alert systems. One reason for this may be that general practitioners (GPs) are overriding these alerts without properly checking them. AIMS:(...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Magnus D,Rodgers S,Avery AJ

更新日期：2002-10-01 00:00:00

abstract：:A single dose pharmacokinetic study was conducted on two sustained-release formulations (75 mg) of indomethacin (Indocid capsules 'A' and Indogesic tablets 'B'). The study was carried out on 22 healthy male volunteers, who received a single oral dose (75 mg) of each product according to a randomized crossover design. ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hasan MM,Najib NM,Muti HY

更新日期：1994-10-01 00:00:00

abstract：:This study involved the mixing of 1:1 combinations of Bactroban (mupirocin) Ointment 2% with various cream, lotion, ointment, gel, solution and liquid soap formulations with storage at 37 degrees C for 60 days. The mixtures were assayed for mupirocin content at 0, 15, 30, 45 and 60 days using a high-pressure liquid ch...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Jagota NK,Stewart JT,Warren FW,John PM

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To find out in child abusing mothers whether aggressiveness in general, but which is directed towards their children in particular, could be reduced by giving lithium. METHOD:An open trial of lithium in eight child-abusing mothers. Assessment of aggression using Yudofsky's Overt Aggression Scale. RESULTS:Th...

journal_title：Journal of clinical pharmacy and therapeutics

authors： do Prado-Lima P,Knijnik L,Juruena M,Padilla A

更新日期：2001-08-01 00:00:00

abstract：:A population pharmacokinetic study was conducted on a total of 70 patients receiving gentamicin therapy. The patients included those with normal renal function and those with varying degrees of renal impairment. The parameters studied were the apparent volume of distribution and the plasma clearance of gentamicin. The...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lanao JM,Berrocal A,Calvo MV,Perez M,de la Calle B,Domínguez-Gil A

更新日期：1989-06-01 00:00:00

abstract：:An imbalance of oxidative-antioxidant defence mechanism has been proposed in systemic lupus erythematosus patients. Co-administration of N-acetylcysteine (NAC) which has a strong antioxidant activity may produce a satisfactory therapeutic outcome when added to standard therapy. We report a case of a 46-year-old lupus ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tewthanom K,Janwitayanujit S,Totemchockcyakarn K,Panomvana Na Ayudhya D

更新日期：2010-08-01 00:00:00

abstract：:The prevailing major theory of Alzheimer's disease (AD) is that insoluble amyloid beta-peptide (Abeta) found in the cerebral plaques characteristic of the disease is causative or is at least a contributing factor. According to this theory, inhibition of aberrant Abeta production should prevent or at least limit the ex...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Maiorini AF,Gaunt MJ,Jacobsen TM,McKay AE,Waldman LD,Raffa RB

更新日期：2002-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:It is well known that medication reconciliation at discharge is a key strategy to ensure proper drug prescription and the effectiveness and safety of any treatment. Different types of interventions to reduce reconciliation errors at discharge have been tested, many of which are based on the ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： García-Molina Sáez C,Urbieta Sanz E,Madrigal de Torres M,Vicente Vera T,Pérez Cárceles MD

更新日期：2016-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Pain management for complex regional pain syndrome (CRPS) is challenging. When added to local anaesthetics, dexmedetomidine prolongs the duration of the block and improves analgesia. The effect of long-term dexmedetomidine use in the brachial plexus block (BPB) for CRPS is unknown. CASE DES...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kang SH,Sim WS,Park HJ,Moon JY,Seon HJ,Lee JY

更新日期：2020-04-01 00:00:00

abstract：:Isradipine is a potent dihydropyridine calcium channel blocker. It is highly selective for vascular smooth muscle, with very few negative inotropic or chronotropic effects. It may have minor depressant effects on the sinoatrial node, hence reducing the incidence of reflex tachycardia. The drug is extensively metaboliz...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Schachter M

更新日期：1991-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The most common complication of heparin therapy is bleeding. Allergic reactions to heparin are rare, and the mechanisms are poorly understood. We report on a case of acute systemic reaction after subcutaneous injections of a low-molecular-weight heparin (LMWH) in a patient with a genetic pre...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Leone S,Zuccoli ML,Fucile C,Storace S,Martelli A,Mattioli F

更新日期：2012-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Demonstration of the utility of electronic medical records (EMRs) for pharmacovigilance (PV) has been highly anticipated. Analysis using appropriately selected EMRs should enable accurate estimation of adverse drug event (ADE) frequencies and thus promote appropriate regulatory actions. Stat...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sai K,Hanatani T,Azuma Y,Segawa K,Tohkin M,Omatsu H,Makimoto H,Hirai M,Saito Y

更新日期：2013-06-01 00:00:00