Arabidopsis PPP family of serine/threonine phosphatases.

Abstract:

:Serine/threonine-specific phosphoprotein phosphatases (PPPs) are ubiquitous enzymes in all eukaryotes, but their regulatory functions are largely unknown in higher plants. The Arabidopsis genome encodes 26 PPP catalytic subunits related to type 1, type 2A and so-called novel phosphatases, including four plant-specific enzymes carrying large N-terminal kelch-domains, but no apparent homologue of the PP2B family. The catalytic subunits of PPPs associate with regulatory protein partners that target them to well defined cellular locations and modulate their activity. Recent studies of phosphatase partners and their interactions have directed attention again to functional dissection of plant PPP families, and highlight their intriguing roles in the regulation of metabolism, cell cycle and development, as well as their roles in light, stress and hormonal signalling.

journal_name

Trends Plant Sci

journal_title

Trends in plant science

authors

Farkas I,Dombrádi V,Miskei M,Szabados L,Koncz C

doi

10.1016/j.tplants.2007.03.003

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

169-76

issue

4

eissn

1360-1385

issn

1878-4372

pii

S1360-1385(07)00057-X

journal_volume

12

pub_type

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