A review of executive functions in obstructive sleep apnea syndrome.


OBJECTIVES:To provide an update on recent research concerning obstructive sleep apnea syndrome (OSAS) and executive functions. METHODS:A systematic review was carried out on reports drawn from MEDLINE and PSYCHLIT (January 1990-December 2005) and identified from lists of references in these reports. The selection criteria were met by 40 articles. RESULTS:The sample sizes in the reviewed studies varied widely and consisted mostly of selected groups. Most patient samples were heterogeneous in terms of the severity of OSAS. Executive functions were generally assessed with standardized test methods. Half of the studies assessed executive functions using only one or two tests. The most defected domains of executive functions were working memory, phonological fluency, cognitive flexibility, and planning. Continuous positive airway pressure (CPAP) treatment improved performance times, cognitive flexibility, and planning. Deficits in working memory and phonological fluency persisted. CONCLUSIONS:Executive functions are the most defected cognitive domain in OSAS. Previous studies are affected by the heterogeneity of patient samples and the definitions of the domains of executive functions. Executive functions in OSAS should be assessed with a standardized neuropsychological test battery including assessments of different domains of executive functions. More research is needed on the efficiency of CPAP treatment on executive dysfunctions.


Acta Neurol Scand


Saunamäki T,Jehkonen M




Has Abstract


2007-01-01 00:00:00














  • Carpal tunnel syndrome and hyperthyroidism. A prospective study.

    abstract::We carried out a prospective study to determine the frequency and evolution of carpal tunnel syndrome (CTS) in patients with hyperthyroidism. An initial survey revealed CTS in 5% of these patients when hyperthyroidism was diagnosed. During the clinical and neurophysiologic follow-up for a two-year period, four more pa...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Roquer J,Cano JF

    更新日期:1993-08-01 00:00:00

  • Juvenile neurolipidosis of Bernheimer-Seitelberger's type. Histopathological and biochemical findings.

    abstract::Two children are reported, who became diseased at the age of 4 and 2 years, respectively, with progressive upper motor neuron symptoms leading to severe disability within a few years. The boy died at age 10 and autopsy disclosed a severe gangliolipidosis throughout the central nervous system, maximal in the brain stem...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Brandt S,Clausen J,Diemer NH,Faurholt-Pedersen V,Jensen GE,Lademann A,Melchior JC

    更新日期:1977-12-01 00:00:00

  • A large Japanese family with Machado-Joseph disease: clinical and genetic studies.

    abstract::A large Japanese family with probable Machado-Joseph disease (MJD) is described. Detailed neurological examination in 12 patients from 3 generations revealed variable combinations of cerebellar ataxia, ocular paresis, difficulty in eye-lid opening, bulging eyes, facial "myokymia", facial dystonia, pyramidal signs, ext...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Takiyama Y,Ikemoto S,Tanaka Y,Mizuno Y,Yoshida M,Yasuda N

    更新日期:1989-03-01 00:00:00

  • Experimental studies and controlled clinical testing of valproate and vigabatrin.

    abstract::Gamma-aminobutyric acid (GABA) is the most important inhibitory transmitter, quantitatively, in the CNS. Evidence exists that decreased GABAergic neurotransmission may play a role in some forms of epilepsy. Consequently, manipulating the GABA system may be a therapeutic possibility in the treatment of this disease. In...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,评审


    authors: Gram L

    更新日期:1988-10-01 00:00:00

  • Benign monoclonal IgAK gammopathy associated with polyneuropathy and dysautonomia.

    abstract::The first case of benign IgAK monoclonal gammopathy associated with peripheral neuropathy is described. Dysautonomia is an unusual, yet prominent, manifestation of neuropathy in this patient. Electrodiagnostic testing and nerve biopsy were compatible with demyelination and axonal loss. Myelin sheath, perineural, and e...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Bailey RO,Ritaccio AL,Bishop MB,Wu AY

    更新日期:1986-06-01 00:00:00

  • A comprehensive electrophysiological evaluation of phrenic nerve injury related to open-heart surgery.

    abstract::A prospective electrophysiological study of phrenic nerve was performed in 59 subjects undergoing open-heart surgery. The nerve was stimulated percutaneously at the neck and the diaphragmatic response was recorded with surface electrodes placed over the 8th intercostal space. The latency, amplitude, duration and area ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Chroni E,Patel RL,Taub N,Venn GE,Howard RS,Panayiotopoulos CP

    更新日期:1995-04-01 00:00:00

  • Caregiver's burden in disorders of consciousness: a longitudinal study.

    abstract:OBJECTIVES:To study the changes in the burden of informal caregivers of patients with disorders of consciousness (DOC) over time. MATERIALS AND METHODS:Short Form-12, Family Strain Questionnaire, Beck Depression Inventory and Coping Orientations to Problem Experiences were administered. RESULTS:Data collected on 216 ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Covelli V,Sattin D,Giovannetti AM,Scaratti C,Willems M,Leonardi M

    更新日期:2016-11-01 00:00:00

  • Progressive supranuclear palsy revisited.

    abstract::Current understanding on the historic, epidemiologic, genetic, clinical, neuropathologic, neurochemical, diagnostic and therapeutic aspects of progressive supranuclear palsy (PSP) are revisited. In addition, new research directions are described. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 更正并重新发布的文章,杂志文章,评审


    authors: Litvan I

    更新日期:1998-12-01 00:00:00

  • Myelin glycosphingolipid immunoreactivity and CSF levels in multiple sclerosis.

    abstract:OBJECTIVES:Patients with multiple sclerosis were reported to harbour antibodies not only against proteins and glycoproteins but also against glycolipids, including sulfatide and galactosylceramide (GalCer), the two major glycosphingolipids of myelin. However, previous results were inconsistent concerning glycosphingoli...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Haghighi S,Lekman A,Nilsson S,Blomqvist M,Andersen O

    更新日期:2012-01-01 00:00:00

  • Influence of carbamazepine on serum thyroxine and triiodothyronine in patients with epilepsy.

    abstract::Hypothyroidism induced by anti-epileptic drug treatment gave rise to thyroid function test studies in patients treated with carbamazepine (CBZ) only. In 42 patients on long-term CBZ treatment thyroxine (T4), free T4-index (FT4I), and triiodothyronine (T3) concentrations in serum were significantly lower than in contro...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Strandjord RE,Aanderud S,Myking OL,Johannessen SI

    更新日期:1981-02-01 00:00:00

  • Methods of measurement of thermal thresholds.

    abstract::Thermal tests were performed in 117 healthy subjects on the face, wrist and leg; 32 were tested on the legs with different rates of cooling and warming. Additionally 2 groups of diabetics (37 patients) were tested. Thermotesting was most sensitive on the legs using a rate of temperature change of 2.5-2.8 oC/s. Warm an...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Claus D,Hilz MJ,Hummer I,Neundörfer B

    更新日期:1987-10-01 00:00:00

  • Musculoskeletal and central pain at 1 year post-stroke: associated factors and impact on quality of life.

    abstract:BACKGROUND AND PURPOSE:Pain is common in post-stroke patients and has been shown to be associated with depression, fatigue, and decreased quality of life (QOL). However, studies examining different types of post-stroke pain are scarce. We investigated differences in the related factors and their QOL impacts between mus...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Choi-Kwon S,Choi SH,Suh M,Choi S,Cho KH,Nah HW,Song H,Kim JS

    更新日期:2017-04-01 00:00:00

  • Oligoclonal immunoglobulin G in cerebrospinal fluid of myasthenia gravis patients.

    abstract::Immunoglobulin G (IgG) band patterns were investigated in cerebrospinal fluid (CSF) from 19 patients with myasthenia gravis (MG) in a search for abnormalities indicating central nervous system (CNS) involvement in this disorder. Using the isoelectric focusing (IEF) technique and antiserum immunoblotting against IgG, w...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Mavra M,Apostolski S,Nikolic J,Thompson EJ

    更新日期:1990-03-01 00:00:00

  • Non-persistence in ischaemic stroke: Risk of recurrent vascular events.

    abstract:OBJECTIVES:Ischaemic stroke is one of the leading causes of death and disability worldwide. Although the secondary preventive medication should be continued for life, its use commonly declines in time. This may lead to recurrent vascular events. In this study, we investigated if during a long follow-up period discontin...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Rijkmans M,de Jong G,van den Berg JSP

    更新日期:2018-03-01 00:00:00

  • Potential role of brivaracetam in pediatric epilepsy.

    abstract::Brivaracetam (BRV) is a new antiseizure medication (ASM) that is currently approved for adjunctive treatment in patients with focal onset seizures. Similarly to levetiracetam (LEV), BRV works by binding SV2A vesicles with a high affinity and a linear pharmacokinetic profile. Retrospective studies and randomized clinic...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Verrotti A,Grasso EA,Cacciatore M,Matricardi S,Striano P

    更新日期:2020-09-23 00:00:00

  • How broad is the phenotype of Hallervorden-Spatz disease?

    abstract::Magnetic resonance imaging (MRI) has enabled ante mortem diagnosis of Hallervorden Spatz disease (HSD). Childhood-onset cases are the most common type and usually present with progressive dystonia and dementia. The duration of illness is 15 to 20 years, leading to death. Presentation in adulthood and infancy have also...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Hickman SJ,Ward NS,Surtees RA,Stevens JM,Farmer SF

    更新日期:2001-03-01 00:00:00

  • Progressive ataxia in Swedish children: a re-evaluation study.

    abstract::The results of follow-up of 76 children with progressive ataxia first reported in 1988 are described with special reference to type of potential underlying metabolic diseases. In 70% of cases the clinical follow-up did not lead to reconsideration of diagnoses. Six of 23 biochemically and morphologically re-examined ch...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Ylitalo V,Hagberg BA

    更新日期:1994-04-01 00:00:00

  • Rising mortality from Parkinson's disease in Japan, 1950-1992.

    abstract::The death rate from Parkinson's disease (PD) were analyzed using Japanese vital statistics for 1950-1992. The age-adjusted PD death rate increased statistically significantly with the years between 1950 and 1992 for both sexes. However, decline in the PD death rate were observed among the population under 65 years old...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Imaizumi Y,Kaneko R

    更新日期:1995-03-01 00:00:00

  • The effect of L-Deprenyl on on-off phenomena in Parkinson's disease.

    abstract::L-Deprenyl, a specific monoamine oxidase subtype B inhibitor, has been reported a valuable adjunct to conventional treatment of Parkinsonism. A double-blind cross-over controlled study was performed in 19 parkinsonian patients with on-off type problems. Five mg L-Deprenyl per day reduced the number of on-off episodes....

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章


    authors: Brodersen P,Philbert A,Gulliksen G,Stigård A

    更新日期:1985-06-01 00:00:00

  • Neurofilament light protein levels in cerebrospinal fluid predict long-term disability of Guillain-Barré syndrome: A pilot study.

    abstract:OBJECTIVES:Although the recovery from Guillain-Barré syndrome (GBS) is good in most patients, some develop permanent severe disability or even die. Early predictors would increase the likelihood to identify patients at risk for poor outcome at the acute stage, allowing them intensified therapeutic intervention. MATERI...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Axelsson M,Sjögren M,Andersen O,Blennow K,Zetterberg H,Lycke J

    更新日期:2018-08-01 00:00:00

  • Electroencephalographic examination of 64 Danish Turner girls.

    abstract::An EEG study of 64 Danish Turner girls and age-matched controls was made. The characteristic findings in the basic EEG rhythms of Turner girls were: 1) alpha activity of more rapid frequency (10.5+ Hz), lower amplitude (-20 microV, lower amount (-30%) and diffuse areas, 2) beta activity of slower frequency (14-18 Hz),...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Tsuboi T,Nielsen J

    更新日期:1985-12-01 00:00:00

  • Prostaglandin E2 is increased in amyotrophic lateral sclerosis patients.

    abstract:OBJECTIVES:Oxidative stress and glutamate-mediated excitotoxicity may play an important role in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). Prostaglandin E2 (PGE2) activity can be associated with motor neuron death by inducing free radical formation and glutamate release from astrocytes. The aim of thi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Iłzecka J

    更新日期:2003-08-01 00:00:00

  • General convulsions and rhabdomyolysis. Case reports.

    abstract::Two patients who developed rhabdomyolysis secondary to generalized seizures are presented. Minor traumas of skeletal muscles due to seizures may be associated with myoglobinuria and the development of acute renal failure. The diagnosis rhabdomyolysis may easily be confirmed by following serum creatine kinase. Myoglobi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Os I,Lyngdal PT

    更新日期:1989-03-01 00:00:00

  • F wave studies after intrathecal methotrexate administration.

    abstract::Electrophysiological examinations were done on 20 patients aged 40-71 years with recently diagnosed high grade non-Hodgkin's lymphomas. General chemotherapy and intrathecal chemotherapy in order to prevent central nervous system (CNS) involvement were begun. On the first day of chemotherapeutic cycle patients received...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Grzelec H,Fryze C,Nowacki P,Zdziarska B

    更新日期:1996-10-01 00:00:00

  • Neuropathy and impaired glucose tolerance: an updated review of the evidence.

    abstract::There has been considerable interest in the possible association between impaired glucose tolerance (IGT) and neuropathy. A systematic literature search (Medline) and review was here performed. Twenty-three studies were evaluated. Fourteen investigated for the presence of neuropathy in patients with IGT. Nine studied ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审


    authors: Rajabally YA

    更新日期:2011-07-01 00:00:00

  • Motor compensation and recovery for reaching in stroke patients.

    abstract:OBJECTIVES:To examine the mechanisms of alternative strategies developed by stroke patients to compensate their motor impairment and their role in recovery. MATERIAL AND METHODS:The three-dimensional kinematics of the upper limb were quantified during unconstrained reaching movements in seven healthy individuals and i...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Roby-Brami A,Feydy A,Combeaud M,Biryukova EV,Bussel B,Levin MF

    更新日期:2003-05-01 00:00:00

  • Temporal lobe epilepsy visualized with PET with 11C-L-deuterium-deprenyl--analysis of kinetic data.

    abstract:OBJECTIVES:The purpose of the study was to develop a simplified method for the acquisition and analysis of data from positron emission tomography (PET) using the ligand 11C-L-deuterium-deprenyl. This is motivated by an increased interest in methods to characterize gliosis in neurodegenerative diseases and epilepsy, whi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章


    authors: Bergström M,Kumlien E,Lilja A,Tyrefors N,Westerberg G,Långström B

    更新日期:1998-10-01 00:00:00

  • Stroke in children under 16 years of age. Clinical and etiological difference with adults.

    abstract:OBJECTIVES:The aim of this study was to re-evaluate the clinical features of stroke in children, their outcome and the place of the different mechanisms, in the light of CT-scan and magnetic resonance imaging. METHODS:A 10-year review of the Dijon Childhood Neurology Clinic experience (1985-1995) identified 54 patient...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Giroud M,Lemesle M,Madinier G,Manceau E,Osseby GV,Dumas R

    更新日期:1997-12-01 00:00:00

  • Oral choline in cerebellar ataxia.

    abstract::In a double-blind crossover pilot study with placebo, choline chloride, the physiologic precursor of acetylcholine, was tested in six patients with cerebellar ataxia. Neither subjectively nor objectively could any statistical significant difference be demonstrated. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Sehested P,Lund HI,Kristensen O

    更新日期:1980-08-01 00:00:00

  • Regional spinal cord blood flow in the rabbit, cat and monkey.

    abstract::Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章


    authors: Nyström B,Stjernschantz J,Smedegård G

    更新日期:1984-10-01 00:00:00