Postresuscitative intensive care: neuroprotective strategies after cardiac arrest.

abstract：:The accumulation of fibrillar α-synuclein protein is the pathological hallmark occurring in both multiple system atrophy (MSA) and diffuse Lewy body disease (DLBD). The oligodendrocytes are especially involved in MSA, while subtypes of neurons are the targets in DLBD. In both instances, the changes are widespread with...

journal_title：Seminars in neurology

authors： Ramirez EP,Vonsattel JP

更新日期：2014-04-01 00:00:00

abstract：:Parkinson's disease (PD) is a significant neurodegenerative disease of the elderly, affecting 1 to 2% of those over 60 years of age. The disorder is characterized by resting tremor, bradykinesia, rigidity, postural instability, and pathologically by alpha-synuclein-positive Lewy bodies. For most, the etiology is unkno...

journal_title：Seminars in neurology

authors： Lorincz MT

更新日期：2006-11-01 00:00:00

abstract：:The traditional view of neuromyelitis optica (NMO) as a monophasic inflammatory disorder that affects both the optic nerves and the spinal cord is expanding. Over the last decade, a combination of clinical, radiological, pathological, and serological findings have resulted in evolving definitions of NMO and the apprec...

journal_title：Seminars in neurology

authors： Pittock SJ

更新日期：2008-02-01 00:00:00

abstract：:The field of neurocritical care has evolved tremendously in recent years, a development explained vastly by the advent of neurophysiological monitoring. From basic intracranial pressure measurements to brain tissue oxygenation, microdialysis, cerebral blood flow (CBF), and surface and intracortical electroencephalogra...

journal_title：Seminars in neurology

authors： Francoeur CL,Pain M,Mayer SA

更新日期：2016-12-01 00:00:00

abstract：:Pseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as idiopathic intracranial hypertension or primary intracranial hypertension, or can be secondary to...

journal_title：Seminars in neurology

authors： Beres SJ

更新日期：2020-06-01 00:00:00

abstract：:Calcineurin inhibitor encephalopathy (CIE) is a rare condition occurring in patients who are undergoing treatment with drugs from the calcineurin inhibitor (CI) family of immunosuppressants, either cyclosporine (CsA) or tacrolimus (TAC, FK506). Generally acute in onset, the symptoms are commonly reversible if properly...

journal_title：Seminars in neurology

authors： Mammoser A

更新日期：2012-11-01 00:00:00

abstract：:Mitochondrial oxidative phosphorylation (OXPHOS) disorders are a heterogeneous group of diseases with variable expression that often pose diagnostic dilemmas. Although definitive diagnosis of these disorders usually requires a muscle biopsy and mtDNA and enzymatic testing, standard metabolic studies including organic ...

journal_title：Seminars in neurology

authors： Dougherty FE

更新日期：2001-09-01 00:00:00

abstract：:Establishing an open and honest physician-patient relationship is essential for the proper evaluation and management of headache disorders. Obtaining a complete headache and medical history is the most important part of the initial diagnostic evaluation. This history should include information about headache onset, pa...

journal_title：Seminars in neurology

authors： Marks DR,Rapoport AM

更新日期：1997-01-01 00:00:00

abstract：:Treatment of dementias represents an important but relatively neglected part of neurological care of the elderly population. Individual therapeutic interventions may make only small changes to the quality of life of individuals afflicted with dementia, but when used in combination these interventions synergize and can...

journal_title：Seminars in neurology

authors： Tisher A,Salardini A

更新日期：2019-04-01 00:00:00

abstract：:Neurotoxic venoms are common among tropical marine creatures, which have specialized apparatuses for delivery of the venoms. These include jellyfish and anemones, venomous cone snails, venomous fish, stingrays, sea snakes, and venomous octopuses. Numerous toxic neuropeptides are found within these venoms, and some can...

journal_title：Seminars in neurology

authors： Watters MR

更新日期：2005-09-01 00:00:00

abstract：:I argue that there is no mind-brain problem but rather that there are irreducible subjective-objective problems. These include the difference between "inside" and "outside" perspectives on neural states, the creation of subjective neural states with objectified outside objects, and awareness of the self as an object i...

journal_title：Seminars in neurology

authors： Feinberg TE

更新日期：1997-06-01 00:00:00

abstract：:CPP reflects perfusion problems related to increased ICP or inadequate MAP. CPP is a most helpful and practical management tool. The relationship of CBF and CPP depends on cerebral vascular resistance (flow equals pressure divided by resistance). At present, we do not have a practical method to measure vascular resist...

journal_title：Seminars in neurology

authors： Stone JL

更新日期：1989-09-01 00:00:00

abstract：:The PPS is now a well-recognized entity encompassing the late manifestations that occur because of previous poliomyelitis. Common signs and symptoms include fatigue, cold intolerance, joint deteriorations with pain, and prominent neurologic problems that include new weakness, muscle pain, atrophy, respiratory insuffic...

journal_title：Seminars in neurology

authors： Jubelt B,Drucker J

更新日期：1993-09-01 00:00:00

abstract：:Both general neurologists and neurologists with a broad spectrum of subspecialty interests are often asked to evaluate patients with disorders of the spinal cord. Over the past decade, there have been significant advances in our understanding of a wide spectrum of immune-mediated, infectious, metabolic, hereditary, pa...

journal_title：Seminars in neurology

authors： Kumar N

更新日期：2010-02-01 00:00:00

abstract：:Chronic insomnia afflicts millions of people in the United States. It is associated with decreased quality of life, accidents, several comorbid conditions, increased morbidity, and substantial direct and indirect costs. Chronic insomnia is a multifactorial and individualized disorder. Its etiology may be cognitive or ...

journal_title：Seminars in neurology

authors： Neubauer DN,Flaherty KN

更新日期：2009-09-01 00:00:00

abstract：:During the last decade, we have witnessed significant advances in the study of inherited dystonias. This article will review some of those discoveries and summarize their significance for the practicing neurologist. A clinical classification of dystonia based on features that can be determined by the clinician is prop...

journal_title：Seminars in neurology

authors： Gonzalez-Alegre P

更新日期：2007-04-01 00:00:00

abstract：:With the increasing acceptance of the right of patients to refuse life-sustaining treatment, some have argued that terminally ill patients have a corollary right to physician-assisted suicide (PAS) on request. However, there are important moral and legal distinctions between patients' refusals of therapy and requests ...

journal_title：Seminars in neurology

authors： Bernat JL

更新日期：1997-01-01 00:00:00

abstract：:The clinical hallmark of myasthenia gravis (MG) is fluctuating, painless weakness of muscles that most often affect extraocular, lower bulbar, or limb musculature. Predicting the probability of successful treatment for the patient assumes that the physician has made an accurate diagnosis. In this review, the practical...

journal_title：Seminars in neurology

authors： Engstrom JW

更新日期：2004-06-01 00:00:00

abstract：:Telemedicine is the use of electronic communication methods, such as the telephone, the Internet, and videoconferencing, to exchange medical information from one geographic site to another. Telestroke is the use of telemedicine specifically for stroke care. A strokologist is a physician with the special skills require...

journal_title：Seminars in neurology

authors： Demaerschalk BM

更新日期：2010-11-01 00:00:00

abstract：:Although there are several animal models of Lyme disease, only the rhesus monkey model exhibits all of the key manifestations of the disease. After infection with Borrelia burgdorferi, rhesus monkeys develop signs of early localized, early disseminated, and chronic Lyme disease. Specific features include erythema migr...

journal_title：Seminars in neurology

authors： England JD,Bohm RP Jr,Roberts ED,Philipp MT

更新日期：1997-03-01 00:00:00

abstract：:Before embarking on expensive ancillary testing, it is crucial for the neurologist to distinguish visual loss due to optic nerve dysfunction from other causes of visual loss. This can usually be accomplished based on specific features of the history and bedside examination. Once it has been established that a patient ...

journal_title：Seminars in neurology

authors： Purvin VA

更新日期：2000-01-01 00:00:00

abstract：:The combination of neurologic disease and ichthyosis defines a heterogeneous group of rare inherited disorders that present in infancy through early adulthood. Although affected patients share the cutaneous feature of ichthyosis, there is variability in the nature and severity of neurologic disease. Impaired cognition...

journal_title：Seminars in neurology

authors： Rizzo WB,Jenkens SM,Boucher P

更新日期：2012-02-01 00:00:00

abstract：:The growth of bioethics as a practical, meaningful player in the arena of health care has paralleled that of clinical neurology not only in time but also in interaction between the two disciplines. Almost every advance in neurology has spawned an ethical dilemma, the unraveling of which has brought new insights to bot...

journal_title：Seminars in neurology

authors： McQuillen MP

更新日期：2001-12-01 00:00:00

abstract：:Infective endocarditis (IE) is a systemic disease with many potential neurologic manifestations including ischemic and hemorrhagic strokes, cerebral microbleeding, infectious intracranial aneurysms, meningitis, brain abscesses, and encephalopathy. The majority of left-sided (heart) IE patients have brain lesions that ...

journal_title：Seminars in neurology

authors： Carneiro TS,Awtry E,Dobrilovic N,Fagan MA,Kimmel S,Weinstein ZM,Cervantes-Arslanian AM

更新日期：2019-08-01 00:00:00

abstract：:With age, the presence of multiple neuropathologies in a single individual becomes increasingly common. Given that traumatic brain injury and the repetitive head impacts (RHIs) that occur in contact sports have been associated with the development of many neurodegenerative diseases, including chronic traumatic encepha...

journal_title：Seminars in neurology

authors： Stein TD,Crary JF

更新日期：2020-08-01 00:00:00

abstract：:Myelopathy refers to a spinal cord disorder that presents with motor and/or sensory deficits. Infectious agents that cause myelopathy do so by either direct infection of neural structures (e.g., polio), a parainfectious mechanism (with a presumed autoimmune pathogenesis), or as a result of involvement of structures ad...

journal_title：Seminars in neurology

authors： Ho EL

更新日期：2012-04-01 00:00:00

abstract：:Synucleinopathies, with and without dementia, encompass a wide range of diseases including Parkinson's disease, multiple system atrophy, rapid eye movement (REM) sleep behavior disorder, and dementia with Lewy bodies (DLB). DLB is a neurodegenerative disorder resulting in slowly progressive and unrelenting dementia un...

journal_title：Seminars in neurology

authors： Weisman D,McKeith I

更新日期：2007-02-01 00:00:00

abstract：:Deficiencies in reading and writing appear to be major and lasting handicaps for learning-disabled college students. However, gains have been made in program modifications for learning-disabled students in many higher education institutions. Many adults with learning disabilities find that their handicap makes it diff...

journal_title：Seminars in neurology

authors： Gottesman RL

更新日期：1991-03-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a very common condition in patients with stroke and is found in over half of stroke patients. There is a complex relationship between OSA and stroke, attributable to shared risk factors. There are numerous mechanisms by which OSA may contribute to increased stroke risk, including promo...

journal_title：Seminars in neurology

authors： Brown DL

更新日期：2006-02-01 00:00:00

abstract：:Sleep medicine can be a particularly rewarding clinical area for neurologists. After all, the driving organ of sleep is the brain. Many of the sleep disorders are primary brain disorders, whereas other sleep disorders (and their medications) influence brain function. But without an organized approach, even the engaged...

journal_title：Seminars in neurology

authors： Ellenbogen JM

更新日期：2016-10-01 00:00:00