Pearls and pitfalls of ethical issues in neurology.

abstract：:The testing of reflexes involving the lower extremities is a pivotal part of the modern neurological examination. The normal response to noxious stimulation of the foot is plantar flexion of the toes, causing them to curl downward toward the undersurface of the foot. In 1896, Joseph Babinski described an extensor toe ...

journal_title：Seminars in neurology

authors： Goetz CG

更新日期：2002-12-01 00:00:00

abstract：:Pain is common but often underrecognized after stroke. Poststroke pain (PSP) hinders recovery, impairs quality of life, and is associated with the psychological state of patients with stroke. The most common subtypes of PSP include central PSP, complex regional pain syndrome, shoulder pain, spasticity-related pain, an...

journal_title：Seminars in neurology

authors： Yang S,Chang MC

更新日期：2021-01-14 00:00:00

abstract：:Dizziness is a common chief complaint with an extensive differential diagnosis that includes both benign and serious conditions. Physicians must distinguish the majority of patients who suffer from self-limiting conditions from those with serious illnesses that require acute treatment. The preferred approach to the di...

journal_title：Seminars in neurology

authors： Gurley KL,Edlow JA

更新日期：2019-02-01 00:00:00

abstract：:Before the AIDS epidemic, progressive multifocal leukoencephalopathy (PML) was a rare disorder occurring most often in association with leukemia and lymphoma. Current estimates indicate that PML ultimately develops in up to 5% of all patients with AIDS. This demyelinating disease results from infection with JC virus, ...

journal_title：Seminars in neurology

authors： Berger JR,Major EO

更新日期：1999-01-01 00:00:00

abstract：:Alteration in neural control from suprapontine areas to the nerves innervating the bladder can lead to bladder dysfunction and the development of a neurogenic bladder (NGB). Patients with NGB often suffer from urinary incontinence, which can lead to adverse events such as urinary tract infections and decubiti, in addi...

journal_title：Seminars in neurology

authors： Smith CP,Chancellor MB

更新日期：2016-02-01 00:00:00

abstract：:Charcot-Marie-Tooth (CMT) disease is caused by mutations in several genes expressed in myelinating Schwann cells and the axons they ensheathe. Typical patients present with distally accentuated motor weakness, muscle wasting, and sensory loss leading to significant and progressive clinical morbidity and impaired quali...

journal_title：Seminars in neurology

authors： Jani-Acsadi A,Krajewski K,Shy ME

更新日期：2008-04-01 00:00:00

abstract：:Metastatic plexopathy is often a disabling accompaniment of advanced systemic cancer and may involve any of the peripheral nerve plexuses. Brachial plexopathy most commonly occurs in carcinoma of the breast and lung; lumbosacral plexopathy is most common with colorectal and gynecologic tumors, sarcomas, and lymphomas....

journal_title：Seminars in neurology

authors： Jaeckle KA

更新日期：2004-12-01 00:00:00

abstract：:Clinical guidelines for the determination of brain death in children were first published in 1987. These guidelines were revised in 2011 under the auspices of the Society of Critical Care Medicine, the American Academy of Pediatrics, and the Child Neurology Society, and provide the minimum standards that must be satis...

journal_title：Seminars in neurology

authors： Mathur M,Ashwal S

更新日期：2015-04-01 00:00:00

abstract：:Deficiencies in reading and writing appear to be major and lasting handicaps for learning-disabled college students. However, gains have been made in program modifications for learning-disabled students in many higher education institutions. Many adults with learning disabilities find that their handicap makes it diff...

journal_title：Seminars in neurology

authors： Gottesman RL

更新日期：1991-03-01 00:00:00

abstract：:Autoimmune epilepsy is increasingly recognized as a distinct clinical entity, driven in large part by the recent discovery of neural autoantibodies in patients with isolated or predominant epilepsy presentations. Detection of neural autoantibodies in high-risk epilepsy patients supports an immune-mediated cause of sei...

journal_title：Seminars in neurology

authors： Quek AML,O'Toole O

更新日期：2018-06-01 00:00:00

abstract：:Although there are several animal models of Lyme disease, only the rhesus monkey model exhibits all of the key manifestations of the disease. After infection with Borrelia burgdorferi, rhesus monkeys develop signs of early localized, early disseminated, and chronic Lyme disease. Specific features include erythema migr...

journal_title：Seminars in neurology

authors： England JD,Bohm RP Jr,Roberts ED,Philipp MT

更新日期：1997-03-01 00:00:00

abstract：:Infective endocarditis (IE) is a systemic disease with many potential neurologic manifestations including ischemic and hemorrhagic strokes, cerebral microbleeding, infectious intracranial aneurysms, meningitis, brain abscesses, and encephalopathy. The majority of left-sided (heart) IE patients have brain lesions that ...

journal_title：Seminars in neurology

authors： Carneiro TS,Awtry E,Dobrilovic N,Fagan MA,Kimmel S,Weinstein ZM,Cervantes-Arslanian AM

更新日期：2019-08-01 00:00:00

abstract：:Primary brain tumors are common causes of focal epilepsy, accounting for 5% of new-onset seizures in adults and over 10% of lesional focal epilepsies. These epilepsies are often refractory to medical treatment, and high rates of seizure freedom can be achieved with gross total resections. However, the management strat...

journal_title：Seminars in neurology

authors： Nowell M,Miserocchi A,McEvoy AW

更新日期：2015-06-01 00:00:00

abstract：:The field of neurocritical care has evolved tremendously in recent years, a development explained vastly by the advent of neurophysiological monitoring. From basic intracranial pressure measurements to brain tissue oxygenation, microdialysis, cerebral blood flow (CBF), and surface and intracortical electroencephalogra...

journal_title：Seminars in neurology

authors： Francoeur CL,Pain M,Mayer SA

更新日期：2016-12-01 00:00:00

abstract：:Upper limb recovery after a stroke is suboptimal. Only a few individuals achieve full functional use of the hemiparetic arm. Complex primary and secondary impairments may affect recovery of upper limb function in stroke survivors. In addition, multiple personal, social, behavioral, economic, and environmental factors ...

journal_title：Seminars in neurology

authors： Tsu AP,Abrams GM,Byl NN

更新日期：2014-11-01 00:00:00

abstract：:Severe brain injury may cause disruption of neural networks that sustain arousal and awareness, the two essential components of consciousness. Despite the potentially devastating immediate and long-term consequences, disorders of consciousness (DoC) are poorly understood in terms of their underlying neurobiology, the ...

journal_title：Seminars in neurology

authors： Bodien YG,Chatelle C,Edlow BL

更新日期：2017-10-01 00:00:00

abstract：:Blepharospasm is a focal dystonia characterized by involuntary, repetitive eye closure. Orofacial and oromandibular dystonia describe involuntary dystonic movements of orofacial and oromandibular musculature. Hemifacial spasm is characterized by repetitive synchronous contraction of facial nerve innervated muscles on ...

journal_title：Seminars in neurology

authors： Karp BI,Alter K

更新日期：2016-02-01 00:00:00

abstract：:Leptomeningeal metastasis occurs in ~5% of all patients with cancer and is the third most common metastatic complication of the central nervous system. Staging of leptomeningeal metastasis includes contrast-enhanced brain and spine magnetic resonance imaging and radionuclide cerebrospinal fluid (CSF) flow study. Treat...

journal_title：Seminars in neurology

authors： Chamberlain MC

更新日期：2010-07-01 00:00:00

abstract：:The optic nerve is our most important cranial nerve. As it courses from the eyeball to the brain, it is divided into four segments: intraocular, intraorbital, intracanalicular, and intracranial. Four tests are primarily used to assess its functional integrity and detect optic nerve disorders. These tests are described...

journal_title：Seminars in neurology

authors： Selhorst JB,Chen Y

更新日期：2009-02-01 00:00:00

abstract：:Status epilepticus is a neurological emergency with an outcome that is highly associated with the initial pharmacotherapy management that must be administered in a timely fashion. Beyond first-line therapy of status epilepticus, treatment is not guided by robust evidence. Optimal pharmacotherapy selection for individu...

journal_title：Seminars in neurology

authors： Der-Nigoghossian C,Tesoro EP,Strein M,Brophy GM

更新日期：2020-12-01 00:00:00

abstract：:Myotonic dystrophies and channelopathies are rare but important causes of muscle diseases which may present with myotonia, episodic attacks of weakness, fixed muscle weakness, and atrophy or their combination. Here, the authors provide an overview of these disorders and describe their clinical and pathophysiological f...

journal_title：Seminars in neurology

authors： Quinn C,Salajegheh MK

更新日期：2015-08-01 00:00:00

abstract：:Before embarking on expensive ancillary testing, it is crucial for the neurologist to distinguish visual loss due to optic nerve dysfunction from other causes of visual loss. This can usually be accomplished based on specific features of the history and bedside examination. Once it has been established that a patient ...

journal_title：Seminars in neurology

authors： Purvin VA

更新日期：2000-01-01 00:00:00

abstract：:With the advent of combination antiretroviral therapies, the mortality rate from HIV has declined, while the prevalence of long-term HIV-related neurologic complications continues to rise. Thirty-six million individuals are living with HIV around the world, many of whom reside in resource-limited settings. The majorit...

journal_title：Seminars in neurology

authors： Patel PB,Spudich SS

更新日期：2018-04-01 00:00:00

abstract：:Fungal central nervous system infections present in a myriad of clinical manifestation and remain a significant diagnostic challenge. Presenting symptoms, cerebrospinal fluid analysis, conventional fungal serum markers and imaging correlates of disease are seldom sensitive or specific; fungal culture growth or histopa...

journal_title：Seminars in neurology

authors： Jia DT,Thakur K

更新日期：2019-06-01 00:00:00

abstract：:Psychoanalysis emerged out of Freud's neuropsychologic studies of consciousness and cognition. This article describes the historical development of neuropsychodynamic theories of consciousness and personality, and traces their application to several neuropsychiatric syndromes of intense contemporary clinical interest....

journal_title：Seminars in neurology

authors： Miller L

更新日期：1997-06-01 00:00:00

abstract：:Carotid endarterectomy is an established surgical procedure to prevent stroke. The indications, preoperative evaluation, surgical timing, technical details, complications, and special circumstances for the use of this operation are reviewed. Future developments in the surgical reconstruction of the extracranial caroti...

journal_title：Seminars in neurology

authors： Pritz MB

更新日期：1998-01-01 00:00:00

abstract：:Severe spastic tone and/or spastic hypertonia can be the most disabling consequences of a neurologic insult, resulting from an excess of muscle tone. Baclofen, a GABA-B agonist, is one of the most widely used drugs in treating abnormal or disabling spastic tone. However, the effectiveness of baclofen taken orally is o...

journal_title：Seminars in neurology

authors： Furr-Stimming E,Boyle AM,Schiess MC

更新日期：2014-11-01 00:00:00

abstract：:Parkinsonism is a clinical syndrome, which is characterized by bradykinesia, rigidity, rest tremor, and postural instability. Idiopathic Parkinson disease (PD) is the most common cause of this syndrome, though there are several other important etiologies that must be considered. These include the atypical Parkinsonian...

journal_title：Seminars in neurology

authors： Keener AM,Bordelon YM

更新日期：2016-08-01 00:00:00

abstract：:The catecholamines dopamine and norepinephrine are key central neurotransmitters that participate in many neurobehavioral processes and disease states. Norepinephrine is also the main neurotransmitter mediating regulation of the circulation by the sympathetic nervous system. Several neurodegenerative disorders feature...

journal_title：Seminars in neurology

authors： Goldstein DS

更新日期：2020-10-01 00:00:00

abstract：:With the development of multiple options for immunotherapy in multiple sclerosis, the clinician is faced with the challenge of keeping pace with the literature, acquiring familiarity with the various treatment options and opinions, and then offering the patients the most current and appropriate management. Given the i...

journal_title：Seminars in neurology

authors： Mattson DH

更新日期：2002-03-01 00:00:00