Lipoprotein-associated phospholipase A2.

abstract：:In marked contrast to their historical classification as relatively harmless, common cold-causing, respiratory pathogens, human coronaviruses (HCoVs) are associated with more severe clinical complications, as emphasized by the discovery of severe acute respiratory syndrome-associated CoV (SARS-CoV) in 2003. Still, the...

journal_title：Clinics in laboratory medicine

authors： Wevers BA,van der Hoek L

更新日期：2009-12-01 00:00:00

abstract：:Bioregulators are naturally occurring organic compounds that regulate a multitude of biologic processes. Under natural circumstances, bioregulators are synthesized in minute quantities in a variety of living organisms and are essential for physiologic homeostasis. In the wrong hands, these compounds have the capabilit...

journal_title：Clinics in laboratory medicine

authors： Kagan E

更新日期：2006-06-01 00:00:00

abstract：:Objective evidence-based national surveys serve as a first step in identifying suitable point-of-care device designs, effective test clusters, and environmental operating conditions. Preliminary survey results show the need for point-of-care testing (POCT) devices using test clusters that specifically detect pathogens...

journal_title：Clinics in laboratory medicine

authors： Kost GJ,Hale KN,Brock TK,Louie RF,Gentile NL,Kitano TK,Tran NK

更新日期：2009-09-01 00:00:00

abstract：:The current success in organ transplantation has been brought about by immunosuppressive therapy. Improvements in transplant outcome using these drugs have stalled, and an understanding of the pharmacogenomics of immunosuppressive dosing and response holds the greatest promise for advancing the use of these agents. ...

journal_title：Clinics in laboratory medicine

authors： Burckart GJ

更新日期：2008-09-01 00:00:00

abstract：:Drug testing of patients in a psychiatric outpatient service is an effective way to identify patients who relapse into renewed use of drugs of abuse and in monitoring the effectiveness of ongoing medical and psychological therapy. Most of this testing involves the analysis of urine specimens with immunoassays. Hair te...

journal_title：Clinics in laboratory medicine

authors： Shearer DS,Baciewicz GJ,Kwong TC

更新日期：1998-12-01 00:00:00

abstract：:The coccidians Cryptosporidium spp, Cyclospora cayetanensis, and Cystoisospora belli and the flagellate Giardia duodenalis are pathogenic protozoa associated with gastrointestinal manifestations. Diagnosis relies heavily on microscopy, and although ova-and-parasite examinations can detect Giardia and Cystoisospora, Cr...

journal_title：Clinics in laboratory medicine

authors： Cama VA,Mathison BA

更新日期：2015-06-01 00:00:00

abstract：:Considerable advances have been made in identifying women whose pregnancies are at the greatest risk for fetal Down syndrome and other aneuploidies. Maternal serum tests and ultrasonography in either the first or second trimester provide effective prenatal screening. However, the most efficacious protocols are based o...

journal_title：Clinics in laboratory medicine

authors： Shamshirsaz AA,Benn P,Egan JF

更新日期：2010-09-01 00:00:00

abstract：:Bacteria were the first organisms recognized for their potential as agents of bioaggression and the possibility of their use by a terrorist or rogue nation is considered a significant threat. Five of the more likely agents (anthrax, plague, tularemia, Q fever, and brucellosis) are reviewed with emphasis on their epide...

journal_title：Clinics in laboratory medicine

authors： Martin GJ,Marty AM

更新日期：2001-09-01 00:00:00

abstract：:The development of antimicrobic susceptibility testing is outlined with particular reference to standardization of procedures and organizational developments that have led to substantially improved performance. Special problems continue to be posed by increased proportions of opportunistic pathogens and newly recogniz...

journal_title：Clinics in laboratory medicine

authors： Sherris JC

更新日期：1989-06-01 00:00:00

abstract：:Lymphoma in dogs is a heterogeneous cancer with highly variable prognosis. Many types of canine lymphoma have similar counterparts in the World Health Organization classification of human lymphoid tumors. The most common variant of canine lymphoma is diffuse large B-cell lymphoma, which, if treated with multiagent che...

journal_title：Clinics in laboratory medicine

authors： Bienzle D,Vernau W

更新日期：2011-03-01 00:00:00

abstract：:With a focus on low-cost and low-power consumption, a miniature laser-induced fluorescence (LIF) detection system was assembled using a 635 nm red diode laser as the excitation source and a photodiode element coupled with an operational amplifier for signal collection. The primary elements of the miniature system, nam...

journal_title：Clinics in laboratory medicine

authors： Shrinivasan S,Norris PM,Landers JP,Ferrance JP

更新日期：2007-03-01 00:00:00

abstract：:This study examines the relationship between D-dimer concentration and patient age, gender, race, and renal function, and the role of D-dimer concentration as a predictor of in-hospital mortality, in a critically ill patient population. The results demonstrate there is a correlation between increased D-dimer concentra...

journal_title：Clinics in laboratory medicine

authors： Spring JL,Winkler A,Levy JH

更新日期：2014-09-01 00:00:00

abstract：:Transfusion medicine is a rapidly evolving specialty, and efforts are ongoing to improve the safety and quality of blood component therapy. Leukocytes are known to be the cause of numerous adverse effects of transfusion therapy, and their removal from red cells and platelet components may be desirable in a variety of ...

journal_title：Clinics in laboratory medicine

authors： Klapper EB,Goldfinger D

更新日期：1992-12-01 00:00:00

abstract：:The interpretation of the total serum testosterone concentration is problematic because it is related directly to the serum SHBG concentration.Frequently, an estimate of the serum free testosterone concentration is obtained to better assess the clinical status of the patient. We reviewed five methods for the determina...

journal_title：Clinics in laboratory medicine

authors： Elin RJ,Winters SJ

更新日期：2004-03-01 00:00:00

abstract：:Technical advances in laboratory testing such as sensitive chemical tests and standardized commercial slides have significantly altered our entire approach to urinalysis. In addition, the recognition of the association of microhematuria with urologic neoplasms and the morphologically altered red blood cells with renal...

journal_title：Clinics in laboratory medicine

authors： Shenoy UA

更新日期：1985-06-01 00:00:00

abstract：:Standard business inventory procedures can be cost effective when they are adapted to hospital laboratory inventory management in a 500-bed hospital. The investment in a central laboratory store-room and one additional employee yields financial benefits and indirect service benefits. The system requires consistent use...

journal_title：Clinics in laboratory medicine

authors： Weinstein W,Wenk RE

更新日期：1985-12-01 00:00:00

abstract：:This article reviews cytomorphology of rare malignant tumors of the breast: squamous carcinoma, metaplastic carcinoma, adenoid cystic carcinoma, apocrine carcinoma, secretory carcinoma, lipid-rich carcinoma, and carcinoma with choriocarcinomatous features. It is important to bear in mind the cytomorphology and diagnos...

journal_title：Clinics in laboratory medicine

authors： Khalbuss WE

更新日期：2005-12-01 00:00:00

abstract：:FNA cytology has been shown to be highly accurate in diagnosing malignant tumors. In gynecology, an overall accuracy of 94.5% in the differentiation between benign and malignant tumors has been reported. Despite many controversial views regarding its safety, aspiration cytology has been accepted as an innocuous proced...

journal_title：Clinics in laboratory medicine

authors： Ganjei P

更新日期：1995-09-01 00:00:00

abstract：:"Bath salts" has attracted young adults primarily due to its stimulatory and hallucinogenic effects akin to amphetamines and cocaine. Although other designer amines have been incorporated to newer generation "bath salts", synthetic cathinones remain to be their major component. This article discusses our current under...

journal_title：Clinics in laboratory medicine

authors： Gerona RR,Wu AH

更新日期：2012-09-01 00:00:00

abstract：:Vertical auto profile (VAP) method is a direct single test for measuring comprehensive lipoprotein cholesterol profile. It is based on a well-established method of ultracentrifugation that uses vertical rotor and single density gradient spin. VAP provides cholesterol concentrations of total lipoprotein, high-density l...

journal_title：Clinics in laboratory medicine

authors： Kulkarni KR

更新日期：2006-12-01 00:00:00

abstract：:Susceptibility testing of microorganisms isolated from blood cultures should follow the guidelines of the NCCLS in the selection of antimicrobial agents and the method for testing. Standardized testing can be performed on isolated colonies from pure subcultures of the blood/broth mixture. Direct susceptibility testing...

journal_title：Clinics in laboratory medicine

authors： Mirrett S

更新日期：1994-03-01 00:00:00

abstract：:Flow cytometry immunophenotyping of the hematopoietic cells from the bone marrow can help with diagnosis, prognosis, and therapy of chronic myeloid neoplasms. Unlike with B-cell neoplasms, there is no simple phenotypic test to substitute for clonality. Therefore, antigen panels to evaluate myeloid neoplasms are larger...

journal_title：Clinics in laboratory medicine

authors： Shi M,Nguyen P,Jevremovic D

更新日期：2017-12-01 00:00:00

abstract：:The cause of colorectal cancer (CRC) is multifactorial, with genetic, molecular, inflammatory, and environmental risk factors. Recently, the gut microbiota has been recognized as a new environmental contributor to CRC in both animal models and human studies. An additional interplay of the gut microbiome with inflammat...

journal_title：Clinics in laboratory medicine

authors： Cho M,Carter J,Harari S,Pei Z

更新日期：2014-12-01 00:00:00

abstract：:A decision model was developed to evaluate the costs and benefits of further reducing the risk of transfusion-transmitted disease. The model addresses recipient risk factors as well as operational considerations. Application of the model to prior risk reduction decisions documents its validity as a decision-making too...

journal_title：Clinics in laboratory medicine

authors： Hanson M

更新日期：1996-12-01 00:00:00

abstract：:To leverage the time and expertise of the pathologist, a comprehensive workstation is a useful tool. Because the practice of pathology is so diverse, however, there is no one standard for what constitutes a workstation. The author reviews the several elements and components which must be included (access to your LIS, ...

journal_title：Clinics in laboratory medicine

authors： Aller RD

更新日期：1997-06-01 00:00:00

abstract：:Salmonella, Shigella, and Yersinia cause a well-characterized spectrum of disease in humans, ranging from asymptomatic carriage to hemorrhagic colitis and fatal typhoidal fever. These pathogens are responsible for millions of cases of food-borne illness in the United States each year, with substantial costs measured i...

journal_title：Clinics in laboratory medicine

authors： Dekker JP,Frank KM

更新日期：2015-06-01 00:00:00

abstract：:The search for clinical outcomes associated with antiphospholipid antibodies (aPL) has been ongoing for a decade. This article focuses on the clinical use of tests for the detection of aPL. A review of the current thinking regarding the pathophysiology of antiphospholipid syndromes is relevant to the discussion of dif...

journal_title：Clinics in laboratory medicine

authors： Reyes H,Dearing L,Bick RL,Shoenfeld Y,Peter JB

更新日期：1995-03-01 00:00:00

abstract：:Although most of the diagnostic applications of flow cytometry bring forth examples of leukocyte immunophenotyping for immunodeficiency diseases and leukemia-lymphoma diagnosis, the same technology has improved medical assessment of diseases affecting the red cell and erythropoiesis. Flow cytometric methods were first...

journal_title：Clinics in laboratory medicine

authors： Davis BH

更新日期：2001-12-01 00:00:00

abstract：:Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequ...

journal_title：Clinics in laboratory medicine

authors： Bhalla A,Zulfiqar M,Weindel M,Shidham VB

更新日期：2013-12-01 00:00:00

abstract：:Recent developments in the surgical pathology of the vulva include updated classifications of non-neoplastic epithelial disorders and vulvar intraepithelial neoplasias. Several histologic variants of vulvar squamous cell carcinoma (SCC) with distinct clinicopathologic features have been described. The concept of super...

journal_title：Clinics in laboratory medicine

authors： Johnson TL

更新日期：1995-09-01 00:00:00