Abstract:
:Fourier transform infrared (FTIR) spectroscopy has long been a powerful tool for structural analysis of membrane proteins. However, because of difficulties in resolving contributions from individual residues, most of the derived measurements tend to yield average properties for the system under study. Isotope editing, through its ability to resolve individual vibrations, establishes FTIR as a method that is capable of yielding accurate structural data on individual sites in a protein.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Arkin ITdoi
10.1016/j.cbpa.2006.08.013subject
Has Abstractpub_date
2006-10-01 00:00:00pages
394-401issue
5eissn
1367-5931issn
1879-0402pii
S1367-5931(06)00120-7journal_volume
10pub_type
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journal_title:Current opinion in chemical biology
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abstract::The rapid growth of bio-sequence information has resulted in an increasing demand for reliable methods that group proteins. A few databases with curated alignments of protein families have demonstrated that expert-driven repositories can keep up with the data deluge in the genome era. These original resources implicit...
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