Development of a module for point-of-care charge capture and submission using an anesthesia information management system.

abstract：BACKGROUND:Adding sodium bicarbonate to lidocaine to enhance its efficacy during peripheral nerve block is controversial. The authors studied the effect of adding sodium bicarbonate to lidocaine with and without epinephrine versus equivalent alkalinization by sodium hydroxide (NaOH) on onset, degree, and duration of pe...

journal_title：Anesthesiology

authors： Sinnott CJ,Garfield JM,Thalhammer JG,Strichartz GR

更新日期：2000-10-01 00:00:00

abstract：:Previous investigators have identified an aortic-to-radial artery pressure gradient thought to develop during rewarming and discontinuation of cardiopulmonary bypass. The authors measured mean aortic and radial artery pressures before, during, and after cardiopulmonary bypass in 30 patients, to determine when the pres...

journal_title：Anesthesiology

authors： Rich GF,Lubanski RE Jr,McLoughlin TM

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The results of sevoflurane biotransformation (fluoromethyl-1,1,1,3,3,3,-hexafluoro-2-propyl ether) to inorganic fluoride have been examined. However, these investigations have lacked a simplified assay for determining the primary organic metabolite, hexafluoroisopropanol. Previous attempts have involved exte...

journal_title：Anesthesiology

authors： Morgan SE,Frink EJ,Gandolfi AJ

更新日期：1994-01-01 00:00:00

abstract：:To determine the percentage of anesthetic metabolized and to assess the role of metabolism in the total elimination of inhaled anesthetics, the authors administered isoflurane, enflurane, halothane, and methoxyflurane simultaneously, for 2 h, to nine healthy patients. Total anesthetic uptake during the 2 h of washin a...

journal_title：Anesthesiology

authors： Carpenter RL,Eger EI 2nd,Johnson BH,Unadkat JD,Sheiner LB

更新日期：1986-08-01 00:00:00

abstract：:The cardiovascular effects of halothane-nitrous oxide anesthesia, and beta-receptor blockade with either propranolol or practolol, were studied in 15 dogs in which severe myocardial infarction had been induced ten days earlier. The hemodynamic responses to blood loss amounting to 25 per cent of estimated blood volume,...

journal_title：Anesthesiology

authors： Prys-Roberts C,Roberts JG,Foëx P,Clarke TN,Bennett MJ,Ryder WA

更新日期：1976-09-01 00:00:00

abstract：:Surgical conditions during conventional mechanical ventilation (CMV) and pulmonary gas exchange were compared with those during high-frequency ventilation (HFV) in 24 patients undergoing anesthesia for intrathoracic surgery. HFV at an oscillatory frequency of 3 Hz and a delivered gas volume of 1.3-1.9 ml/kg provided e...

journal_title：Anesthesiology

authors： Glenski JA,Crawford M,Rehder K

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Pneumocephalus occurs in a variety of clinical settings and has important anesthetic implications, particularly if N2O is used. One common cause of pneumocephalus is a craniotomy or craniectomy, and therefore, patients undergoing these neurosurgical procedures may be at increased risk for the development of ...

journal_title：Anesthesiology

authors： Reasoner DK,Todd MM,Scamman FL,Warner DS

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Despite the fact that obesity is a known risk factor for cardiovascular disease, many studies have failed to demonstrate that obesity is independently associated with an increased risk of cardiovascular morbidity and mortality in nondiabetic patients undergoing coronary artery bypass graft surgery. The autho...

journal_title：Anesthesiology

authors： Pan W,Hindler K,Lee VV,Vaughn WK,Collard CD

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Vascular endothelium plays an important role in the regulation of vascular tone. Volatile anesthetics have been shown to attenuate endothelium-mediated relaxation in conductance arteries, such as aorta. However, significant differences in volatile anesthetic pharmacology between these large vessels and the s...

journal_title：Anesthesiology

authors： Akata T,Nakashima M,Kodama K,Boyle WA 3rd,Takahashi S

更新日期：1995-01-01 00:00:00

abstract：:The inhibitory effects of three inhalation anesthetics, i.e., halothane, enflurane, and isoflurane, on superoxide production and the intracellular mobilization of calcium in human neutrophils were studied. The superoxide production induced by N-formyl-methionyl-leucyl-phenylalanine (FMLP) was inhibited by the anesthet...

journal_title：Anesthesiology

authors： Nakagawara M,Takeshige K,Takamatsu J,Takahashi S,Yoshitake J,Minakami S

更新日期：1986-01-01 00:00:00

abstract：:Dexmedetomidine (DMED) is a highly selective centrally acting alpha 2-adrenergic agonist thought to provide significant sedation without appreciable ventilatory effects. This double-blind, placebo-controlled experiment evaluated four dose levels of DMED (0.25, 0.5, 1.0, and 2.0 micrograms/kg intravenously over 2 min) ...

journal_title：Anesthesiology

authors： Belleville JP,Ward DS,Bloor BC,Maze M

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Investigators in the authors' laboratory previously established the critical participation of the cerulospinal noradrenergic pathway in muscular rigidity elicited by fentanyl. The identification of colocalization of glutamate with tyrosine hydroxylase in most locus ceruleus neurons suggests a role for cerulo...

journal_title：Anesthesiology

authors： Fu MJ,Tsen LY,Lee TY,Lui PW,Chan SH

更新日期：1997-12-01 00:00:00

abstract：:The effect of hypocapnia on autoregulation of cerebral blood flow (CBF) and the lower limit of autoregulation (LLA) was determined in dogs anesthetized with nitrous oxide (66%) and halothane (0.2%, end-expired concentration). CBF and cerebral vascular resistance (CVR) were determined during both normocapnia and hypoca...

journal_title：Anesthesiology

authors： Artru AA,Katz RA,Colley PS

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:The long-lasting high-affinity opioid buprenorphine has complex pharmacology, including ceiling effects with respect to analgesia and respiratory depression. Plasma concentrations of the major buprenorphine metabolites norbuprenorphine, buprenorphine-3-glucuronide, and norbuprenorphine-3-glucuronide approxim...

journal_title：Anesthesiology

authors： Brown SM,Holtzman M,Kim T,Kharasch ED

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The decision to extubate brain-injured patients with residual impaired consciousness holds a high degree of uncertainty of success. The authors developed a pragmatic clinical score predictive of extubation failure in brain-injured patients. METHODS:One hundred and forty brain-injured patients were prospecti...

journal_title：Anesthesiology

authors： Godet T,Chabanne R,Marin J,Kauffmann S,Futier E,Pereira B,Constantin JM

更新日期：2017-01-01 00:00:00

abstract：:It is a common practice for anesthesia to substitute for one another, especially for short breaks during long surgical procedures. The assets and liabilities of this practice of relief have not been examined previously. In the course of gathering 1,089 reports of preventable errors and failures associated with anesthe...

journal_title：Anesthesiology

authors： Cooper JB,Long CD,Newbower RS,Philip JH

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Enflurane and isoflurane are structural isomers with different anesthetic potencies and side effects. It is not clear whether these differences are produced by differing occupancy of common protein binding sites or by occupancy of different sites, but the very similar molecular properties make the latter pos...

journal_title：Anesthesiology

authors： Liu R,Eckenhoff RG

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Sevoflurane is commonly used for cervical cancer surgery, but its effect on cervical cancer cell biology remains unclear. This mechanistic study explores how sevoflurane affects the proliferation and metastatic potential of immortalized cervical cancer cell lines. METHODS:Cultured cervical cancer Caski and ...

journal_title：Anesthesiology

authors： Zhang W,Sheng B,Chen S,Zhao H,Wu L,Sun Y,Cui J,Zhu X,Ma D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Renal and hepatic toxicity of the fluorinated ether volatile anesthetics is caused by biotransformation to toxic metabolites. Metabolism also contributes significantly to the elimination pharmacokinetics of some volatile agents. Although innumerable studies have explored anesthetic metabolism in animals, the...

journal_title：Anesthesiology

authors： Kharasch ED,Thummel KE

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Glutamate has been implicated in the pathophysiology of neuronal injury associated with cerebral hypoxia-ischemia. A model using chronic in utero microdialysis was developed to sample the extracellular space of the fetal brain. Using this model, we tested the hypothesis that glutamate efflux from the parasag...

journal_title：Anesthesiology

authors： Penning DH,Chestnut DH,Dexter F,Hrdy J,Poduska D,Atkins B

更新日期：1995-02-01 00:00:00

abstract：:Inorganic fluoride (F-) production and renal function were assessed in six groups of Fischer 344 rats administered either methoxyflurane (MOF) or deuterated methoxyflurane (d4-MOF). One untreated and one phenobarbital (PB)-treated group were exposed for two hours to either air, 0.5 per cent (V/v) MOF, or 0.5 per cent ...

journal_title：Anesthesiology

authors： Baden JM,Rice SA,Mazze RI

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Perioperative thoracic epidural analgesia reduces stress response and pain scores and may improve outcome after cardiac surgery. This prospective, randomized trial was designed to compare the effectiveness of patient-controlled thoracic epidural analgesia with patient-controlled analgesia with intravenous mo...

journal_title：Anesthesiology

authors： Hansdottir V,Philip J,Olsen MF,Eduard C,Houltz E,Ricksten SE

更新日期：2006-01-01 00:00:00

abstract：:Rats were given standardized injections of 3H-L-proline into the trigeminal ganglion and 14C-lidocaine hydrochloride at the infraorbital foramen. The 3H-L-proline was always injected 2.5 h before removal of the nerve. Lidocaine, 1, 2, and 4%, produced a concentration-related inhibition of entry of 3H-labeled rapid axo...

journal_title：Anesthesiology

authors： Fink BR,Kish SJ

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors mediate fast excitatory synaptic transmission in the central nervous system. Although barbiturates have been shown to suppress the AMPA receptor-mediated responses, it is unclear whether this effect contributes to the a...

journal_title：Anesthesiology

authors： Kamiya Y,Andoh T,Furuya R,Hattori S,Watanabe I,Sasaki T,Ito H,Okumura F

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Several investigations into brain activation caused by pain have suggested that the multiple painful stimulations used in typical block designs may cause attenuation over time of the signal within activated areas. The effect this may have on pain investigations using multiple tasks has not been investigated....

journal_title：Anesthesiology

authors： Ibinson JW,Small RH,Algaze A,Roberts CJ,Clark DL,Schmalbrock P

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Glucose-insulin-potassium (GIK) administration during cardiac surgery inconsistently improves myocardial function, perhaps because hyperglycemia negates the beneficial effects of GIK. The hyperinsulinemic normoglycemic clamp (HNC) technique may better enhance the myocardial benefits of GIK. The authors exten...

journal_title：Anesthesiology

authors： Duncan AE,Kateby Kashy B,Sarwar S,Singh A,Stenina-Adognravi O,Christoffersen S,Alfirevic A,Sale S,Yang D,Thomas JD,Gillinov M,Sessler DI

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to characterize cervical cord, root, and bony spine claims in the American Society of Anesthesiologists Closed Claims database to formulate hypotheses regarding mechanisms of injury. METHODS:All general anesthesia claims (1970-2007) in the Closed Claims database were searched to id...

journal_title：Anesthesiology

authors： Hindman BJ,Palecek JP,Posner KL,Traynelis VC,Lee LA,Sawin PD,Tredway TL,Todd MM,Domino KB

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Impaired cardiac repolarization, indicated by prolonged QT interval, may cause critical ventricular arrhythmias. Many anesthetics increase the QT interval by blockade of rapidly acting potassium rectifier channels. Although xenon does not affect these channels in isolated cardiomyocytes, the authors hypothes...

journal_title：Anesthesiology

authors： Neukirchen M,Schaefer MS,Kern C,Brett S,Werdehausen R,Rellecke P,Reyle-Hahn M,Kienbaum P

更新日期：2015-09-01 00:00:00

abstract：:Although suppression of thermoregulatory mechanisms by anesthetics is generally assumed, the extent to which thermoregulation is active during general anesthesia is not known. The only thermoregulatory responses available to anesthetized, hypothermic patients are vasoconstriction and non-shivering thermogenesis. To te...

journal_title：Anesthesiology

authors： Sessler DI,Olofsson CI,Rubinstein EH,Beebe JJ

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Furosemide and mannitol are used to reduce intracranial pressure, but the impact of furosemide on edema of injured brain is unclear. The authors examined the effects of furosemide and mannitol, alone and in combination, on brain water content in brain-injured rats. METHODS:Anesthetized rats were subjected t...

journal_title：Anesthesiology

authors： Todd MM,Cutkomp J,Brian JE

更新日期：2006-12-01 00:00:00