High-frequency, small-volume ventilation during thoracic surgery.

abstract：BACKGROUND:Spontaneous tremor is relatively common in normothermic patients after operation and has been attributed to many causes. The hypothesis that nonthermoregulatory shivering-like tremor is facilitated by postoperative pain was tested. In addition, the effects of intravenous lidocaine on nonthermoregulatory trem...

journal_title：Anesthesiology

authors： Horn EP,Schroeder F,Wilhelm S,Sessler DI,Standl T,von dem Busche K,Schulte am Esch J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Vascular endothelium plays an important role in the regulation of vascular tone. Volatile anesthetics have been shown to attenuate endothelium-mediated relaxation in conductance arteries, such as aorta. However, significant differences in volatile anesthetic pharmacology between these large vessels and the s...

journal_title：Anesthesiology

authors： Akata T,Nakashima M,Kodama K,Boyle WA 3rd,Takahashi S

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") can mediate acute toxic effects such as muscle rigidity, metabolic acidosis, and hyperthermia. Because of close clinical similarities, an association between MDMA intoxication and malignant hyperthermia (MH) was suggested. The aim of this study was to inves...

journal_title：Anesthesiology

authors： Fiege M,Wappler F,Weisshorn R,Gerbershagen MU,Menge M,Schulte Am Esch J

更新日期：2003-11-01 00:00:00

abstract：:Ten patients with parenchymal acute respiratory failure (ARF) underwent computed tomography (CT) scans while in the supine and prone positions. At equal levels of positive end-expiratory pressure, the authors measured the changes of CT density in dorsal and ventral basilar lung regions induced by the change of positio...

journal_title：Anesthesiology

authors： Gattinoni L,Pelosi P,Vitale G,Pesenti A,D'Andrea L,Mascheroni D

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:During experimental cardiac arrest, continuous insufflation of air or oxygen (CIO) through microcannulas inserted into the inner wall of a modified intubation tube and generating a permanent positive intrathoracic pressure, combined with external cardiac massage, has previously been shown to be as effective ...

journal_title：Anesthesiology

authors： Saïssy JM,Boussignac G,Cheptel E,Rouvin B,Fontaine D,Bargues L,Levecque JP,Michel A,Brochard L

更新日期：2000-06-01 00:00:00

abstract：:This study examined whether pain or stress can enhance the analgesic effects of spinally administered opiates. The experiments determined the effects of mechanically produced pain and of the stress of being restrained on the analgesic effects of 0.63 microgram of epidural sufentanil in rats using a tail-withdrawal pro...

journal_title：Anesthesiology

authors： Van den Hoogen RH,Bervoets K,Colpaert FC

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:The incidence of awareness has been reported to be higher in children than in adults. Accurately assessing awareness in children is difficult, and the lack of a specific measure of awareness makes it difficult to determine exactly how many and why children are aware. The aim of this study was to determine th...

journal_title：Anesthesiology

authors： Davidson AJ,Sheppard SJ,Engwerda AL,Wong A,Phelan L,Ironfield CM,Stargatt R

更新日期：2008-10-01 00:00:00

abstract：:Four volunteers judged eight levels of thermal stimuli induced by a Hardy dolorimeter, varying in intensity from extremely painful to a low level seldom even perceived. Half of the 406 stimuli were applied during acupuncture and half either before insertion or after removal of the needles. The experimental design mini...

journal_title：Anesthesiology

authors： Day RL,Kitahata LM,Kao FF,Motoyama EK,Hardy JD

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Perioperative beta-blockade has been shown to improve long-term cardiac outcome in noncardiac surgical patients. A possible mechanism for the reduced risk of perioperative myocardial infarction is the attenuation of the excitotoxic effects of catecholamine surges by beta-blockade. It was hypothesized that be...

journal_title：Anesthesiology

authors： Zaugg M,Tagliente T,Lucchinetti E,Jacobs E,Krol M,Bodian C,Reich DL,Silverstein JH

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Few data support an association between blood pressure variability and clinical outcomes during cardiac surgery. We tested the hypothesis that intraoperative systolic blood pressure variability outside a targeted blood pressure range predicts 30-day mortality in patients undergoing cardiac surgery. METHODS:...

journal_title：Anesthesiology

authors： Aronson S,Stafford-Smith M,Phillips-Bute B,Shaw A,Gaca J,Newman M,Cardiothoracic Anesthesiology Research Endeavors.

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Propofol is widely used clinically for the induction and maintenance of anesthesia. Clinical case reports have shown that propofol has an antiatrial tachycardia/fibrillation effect; however, the related ionic mechanisms are not fully understood. The current study investigates the effects of propofol on human...

journal_title：Anesthesiology

authors： Yang L,Liu H,Sun HY,Li GR

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Glutamate has been implicated in the pathophysiology of neuronal injury associated with cerebral hypoxia-ischemia. A model using chronic in utero microdialysis was developed to sample the extracellular space of the fetal brain. Using this model, we tested the hypothesis that glutamate efflux from the parasag...

journal_title：Anesthesiology

authors： Penning DH,Chestnut DH,Dexter F,Hrdy J,Poduska D,Atkins B

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:It is increasingly important to evaluate patients' recovery after ambulatory surgery. The authors developed the Functional Recovery Index (FRI) to assess postdischarge functional recovery for ambulatory surgical patients. METHODS:The scale development involved four phases: item generation, item selection, r...

journal_title：Anesthesiology

authors： Wong J,Tong D,De Silva Y,Abrishami A,Chung F

更新日期：2009-03-01 00:00:00

abstract：:Propofol is a potent lipophilic anesthetic that was initially formulated in Cremophor El for human use. Because of the occurrence of Cremophor EL anaphylaxis and improvements in the quality of lipid emulsions, it was ultimately brought to market as 1% propofol formulated in 10% soybean oil emulsion. Emulsions represen...

journal_title：Anesthesiology

authors： Baker MT,Naguib M

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Recent advances have indicated a complex interplay between the autonomic nervous system and the innate immune system. Targeting neural networks for the treatment of sepsis is being developed as a therapeutic strategy. Because electroacupuncture at select acupoints can modulate activities of the autonomic ner...

journal_title：Anesthesiology

authors： Song JG,Li HH,Cao YF,Lv X,Zhang P,Li YS,Zheng YJ,Li Q,Yin PH,Song SL,Wang HY,Wang XR

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Amitriptyline has been reported to be a more potent local anesthetic than bupivacaine. In keeping with the objective of identifying drugs for prolonged cutaneous analgesia, the authors compared the cutaneous analgesic effectiveness of amitriptyline and bupivacaine in rats. METHODS:Rats were subcutaneously i...

journal_title：Anesthesiology

authors： Khan MA,Gerner P,Kuo Wang G

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Halogenated anesthetics potentiate the positive inotropic effects of alpha- and beta-adrenoceptor stimulations. Although diabetes mellitus induces significant myocardial abnormalities, the interaction of halogenated anesthetics and adrenoceptor stimulation in diabetic myocardium remains unknown. METHODS:Lef...

journal_title：Anesthesiology

authors： Amour J,David JS,Vivien B,Coriat P,Riou B

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Mortality after noncardiac surgery has been associated with the "triple low state," a combination of low mean arterial blood pressure (<75 mmHg), low bispectral index (<45), and low minimum alveolar concentration of volatile anesthesia (<0.70). The authors set out to determine whether duration of a triple lo...

journal_title：Anesthesiology

authors： Kertai MD,White WD,Gan TJ

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:: Recent population studies have suggested that children with multiple exposures to anesthesia and surgery at an early age are at an increased risk of cognitive impairment. The authors therefore have established an animal model with single versus multiple exposures of anesthetic(s) in young versus adult mice...

journal_title：Anesthesiology

authors： Shen X,Dong Y,Xu Z,Wang H,Miao C,Soriano SG,Sun D,Baxter MG,Zhang Y,Xie Z

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Combining a hypnotic and an analgesic to produce sedation, analgesia, and surgical immobility required for clinical anesthesia is more common than administration of a volatile anesthetic alone. The aim of this study was to apply response surface methods to characterize the interactions between remifentanil a...

journal_title：Anesthesiology

authors： Manyam SC,Gupta DK,Johnson KB,White JL,Pace NL,Westenskow DR,Egan TD

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:(human ether-a-gogo related gene) encodes the cardiac rapidly activating delayed rectifier potassium currents (I(kr)), which play an important role in cardiac action potential repolarization. General anesthetics, like halothane, can prolong Q-T interval, suggesting that they act on myocellular repolarization...

journal_title：Anesthesiology

authors： Li J,Correa AM

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Rapid development of acute opioid tolerance is well established in animals and is more likely to occur with large doses of short-acting drugs. The authors therefore tested the hypothesis that intraoperative remifentanil administration results in acute opioid tolerance that is manifested by increased postoper...

journal_title：Anesthesiology

authors： Guignard B,Bossard AE,Coste C,Sessler DI,Lebrault C,Alfonsi P,Fletcher D,Chauvin M

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Succinylcholine causes immediate and severe arterial hypotension in swine with the malignant hyperthermia phenotype. The underlying mechanisms are unknown. METHODS:Malignant hyperthermia-susceptible (MHS; n = 10) and normal swine (n = 5) were anesthetized with thiopental. The following were monitored: elect...

journal_title：Anesthesiology

authors： Sigg DC,Iaizzo PA

更新日期：2000-06-01 00:00:00

abstract：:The effects of continuous positive airway pressure (CPAP) on cardiovascular dynamics and pulmonary shunt (QS/QT) were investigated in 12 dogs before and during sodium nitroprusside infusion that decreased mean arterial blood pressure 40-50 per cent. Before nitroprusside infusion, 5 cm H2O CPAP significantly, P less th...

journal_title：Anesthesiology

authors： Hodges MR,Stanley TH,Johansen RK

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:It has been reported that opioid antinociceptive effects are enhanced in animal models of inflammation, but it remains unclear whether this sensitization to morphine is related to predominant central or peripheral increased effects. METHODS:The authors compared the behavioral effects of intraplantar and int...

journal_title：Anesthesiology

authors： Perrot S,Guilbaud G,Kayser V

更新日期：2001-05-01 00:00:00

abstract：:The revised model of coagulation has implications for therapy of both hemorrhagic and thrombotic disorders. Of particular interest to anesthesiologists is the management of clotting abnormalities before, during, and after surgery. Most hereditary and acquired coagulation factor deficiencies can be managed by specific ...

journal_title：Anesthesiology

authors： Roberts HR,Monroe DM,Escobar MA

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction is common, but it remains unclear whether there are long-term adverse cognitive effects of surgery combined with anesthesia. The authors examined the association between exposure to surgery and level of cognitive functioning in a sample of 8,503 middle-aged and elderly twi...

journal_title：Anesthesiology

authors： Dokkedal U,Hansen TG,Rasmussen LS,Mengel-From J,Christensen K

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Ketamine has been associated with a unique spectrum of subjective "psychedelic" effects in patients emerging from anesthesia. This study quantified these effects of ketamine and related them to steady-state plasma concentrations. METHODS:Ketamine or saline was administered in a single-blinded crossover prot...

journal_title：Anesthesiology

authors： Bowdle TA,Radant AD,Cowley DS,Kharasch ED,Strassman RJ,Roy-Byrne PP

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The mechanisms of action of general anesthetics are not completely understood. Many general anesthetics are reported to potentiate gamma-aminobutyric acid (GABAA) and glycine receptors in the central nervous system (CNS) and to inhibit the muscle-type nicotinic acetylcholine receptor (nAChR). The effects of ...

journal_title：Anesthesiology

authors： Flood P,Ramirez-Latorre J,Role L

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Local anesthetics that produce analgesia of long duration with minimal impairment of autonomic functions are highly desirable for pain management in the clinic. Prenylamine is a known calcium channel blocker, but its local anesthetic blocking effects on voltage-gated sodium channels have not been studied thu...

journal_title：Anesthesiology

authors： Mujtaba MG,Gerner P,Wang GK

更新日期：2001-11-01 00:00:00