Abstract:
:Documentation of Chinese materia medica (CMM) dates back to around 1,100 BC when only dozens of drugs were first described. By the end of the 16th century, the number of drugs documented had reached close to 1,900. And by the end of the last century, published records of CMM have reached 12,800 drugs. The recorded traditional information includes toxicities, incompatibilities, cautions, precautions and contraindications. Thus, contrary to a general misconception, toxicity data on Chinese herbs exist and are not meager. If consulted properly before embarking on a study of CMM, it will save researchers much time and efforts and the frustration of not obtaining consistent or expected results. The history of documentation is reviewed with examples of major classic and contemporary works highlighting and emphasizing the manner in which CMM toxicities have traditionally been documented through clinical experience as opposed to most modern toxicity data that are based on animal experimentation.
journal_name
Toxicol Patholjournal_title
Toxicologic pathologyauthors
Leung AYdoi
10.1080/01926230600773958subject
Has Abstractpub_date
2006-01-01 00:00:00pages
319-26issue
4eissn
0192-6233issn
1533-1601pii
W15M37R0M217G232journal_volume
34pub_type
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