Abstract：
UNLABELLED:Two recently identified glucose transporters, GLUT8 and GLUT12, are expressed in human skeletal muscle and may be involved in insulin-mediated sugar transport. PURPOSE:The purpose of this study was to measure GLUT8 and GLUT12 mRNA levels in endurance-trained versus sedentary individuals in an effort to determine the effect of repeated days of contractile activity on gene expression. METHODS:GLUT 4, 8, and 12 mRNA were measured in biopsies from the vastus lateralis using quantitative real-time PCR in endurance-trained (N=16, age=22.0+/-0.9 yr, VO(2 max) (L.min(-1))=4.13+/-0.25) and sedentary (N=15, age=21.3+/-0.8 yr, VO(2 max) (L.min(-1))=3.21+/-0.24) subjects. RESULTS:GLUT12 mRNA was lower (40+/-14%, P<0.05) in the exercise-trained compared with the sedentary subjects. There was no difference between groups in GLUT8 mRNA content. mRNA of the insulin-sensitive glucose transporter (GLUT4) was 78+/-27% (P<0.05) higher in skeletal muscle from endurance-trained compared with sedentary individuals. CONCLUSION:These findings suggest an isoform-specific effect on the mRNA of the glucose transporters in human skeletal muscle with repeated days of contractile activity.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Seki Y,Berggren JR,Houmard JA,Charron MJdoi
10.1249/01.mss.0000222837.74015.f1subject
Has Abstractpub_date
2006-06-01 00:00:00pages
1088-92issue
6eissn
0195-9131issn
1530-0315pii
00005768-200606000-00011journal_volume
38pub_type
杂志文章abstract：PURPOSE:Deceptive manipulations of performance intensity have previously been investigated in cycling time trials (TT) but used different magnitudes, methods, and task durations. This study examines previously used magnitudes of deception during 16.1-km TT and explores yet unexamined psychological responses. METHODS:T...
journal_title：Medicine and science in sports and exercise
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doi：10.1249/MSS.0000000000000694
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001348
更新日期：2017-11-01 00:00:00
abstract：UNLABELLED:A new accelerometer, the Kenz Lifecorder EX (LC; Suzuken Co. Ltd, Nagoya, Japan), offers promise as a feasible monitor alternative to the commonly used Actigraph (AG: Actigraph LLC, Fort Walton Beach, FL). PURPOSE:This study compared the LC and AG accelerometers and the Yamax SW-200 pedometer (DW) under fre...
journal_title：Medicine and science in sports and exercise
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doi：10.1249/mss.0b013e3180313056
更新日期：2007-04-01 00:00:00
abstract：PURPOSE:To investigate muscle deoxygenation and neural drive-related changes during repeated cycling sprints in a fatiguing context. METHODS:Nine healthy male subjects performed a repeated-sprint test (consisting of 10 x 6-s maximal sprints interspaced by 30 s of recovery). Oxygen uptake was measured breath-by-breath;...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000251775.46460.cb
更新日期：2007-02-01 00:00:00
abstract：PURPOSE:The purpose of this paper was to determine whether differences in hemoglobin (Hb) and muscle aerobic capacity exist between African-American (AA) and Caucasian (CA) premenopausal women and to determine whether Hb and aerobic capacity of the muscle are associated with the racial differences in maximum oxygen upt...
journal_title：Medicine and science in sports and exercise
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doi：10.1097/00005768-200110000-00019
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journal_title：Medicine and science in sports and exercise
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doi：10.1249/mss.0b013e3180574e0e
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199902000-00004
更新日期：1999-02-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1097/00005768-199907000-00011
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1991-07-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1249/00005768-199301000-00022
更新日期：1993-01-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002224
更新日期：2020-05-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200112000-00014
更新日期：2001-12-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002493
更新日期：2020-08-15 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002502
更新日期：2020-08-28 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
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更新日期：2006-11-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：2018-11-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199811000-00015
更新日期：1998-11-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-199507000-00012
更新日期：1995-07-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：1997-03-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000064937.99001.56
更新日期：2003-05-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：2010-12-01 00:00:00
