Time-resolved rapid-scan Fourier transform infrared difference spectroscopy on a noncyclic photosystem: rhodopsin photointermediates from Lumi to Meta II.

abstract：:Glycopeptide analogues of CSF114(Glc), modified at N-terminus with new ferrocenyl carboxylic acid and a new ferrocenyl-thiphosphino amino acid, were used to implement a new electrochemical biosensor for autoantibody detection in multiple sclerosis. The ferrocenyl moiety of these "electrochemical probes" did not affect...

journal_title：Biopolymers

authors： Real-Fernández F,Colson A,Bayardon J,Nuti F,Peroni E,Meunier-Prest R,Lolli F,Chelli M,Darcel C,Jugé S,Papini AM

更新日期：2008-01-01 00:00:00

abstract：:A three-dimensional model of DNA/RNA triple helix that contains a poly(L-deoxyadenosine) (L-dA) chain is proposed based on computer-assisted model building and energy calculations. The model building was performed by a new method that systematically searches possible conformations of nucleotide units in the helical ch...

journal_title：Biopolymers

authors： Tomioka N,Itai A

更新日期：1992-12-01 00:00:00

abstract：:Antibacterial properties of the secretion from the female reproductive accessory glands of medfly Ceratitis capitata are mostly ascribed to the presence of two peptides, ceratotoxin A and B, which exhibit a strong activity against gram-positive and gram-negative bacterial strains, and show sequence and function homolo...

journal_title：Biopolymers

authors： Ragona L,Molinari H,Zetta L,Longhi R,Marchini D,Dallai R,Bernini LF,Lozzi L,Scarselli M,Niccolai N

更新日期：1996-11-01 00:00:00

abstract：:An increasing number of RNAs are being discovered that perform their functions by undergoing large changes in conformation in response to a variety of cellular signals, including recognition of proteins and small molecular targets, changes in temperature, and RNA synthesis itself. The measurement of NMR residual dipol...

journal_title：Biopolymers

authors： Getz M,Sun X,Casiano-Negroni A,Zhang Q,Al-Hashimi HM

更新日期：2007-08-05 00:00:00

abstract：:Collagen is a natural protein, which is used as a vital biomaterial in tissue engineering. The major concern about native collagen is lack of its thermal stability and weak resistance to proteolytic degradation. In this scenario, the crosslinking compounds used for stabilization of collagen are mostly of chemical natu...

journal_title：Biopolymers

authors： Usharani N,Jayakumar GC,Kanth SV,Rao JR

更新日期：2014-08-01 00:00:00

abstract：:The conformational behavior of the synthetic peptide, Boc-Gly-Val-Gly-Gly-Leu-OMe, containing the X-Gly-Gly and Gly-Gly-X (X = Val or Leu) repeating sequences and constituting a fragment of elastin was investigated by molecular mechanics and molecular dynamics (MD) simulation. The results suggest that, irrespective of...

journal_title：Biopolymers

authors： Lelj F,Tamburro AM,Villani V,Grimaldi P,Guantieri V

更新日期：1992-02-01 00:00:00

abstract：:The HPLC retention behavior of three complete single methionine and methionine sulfoxide replacement sets of two 18-mer model peptides and neuropeptide Y (NPY) were investigated. All peptides were prepared by multiple solid-phase peptide synthesis. Plotting the retention time differences between methionine and methion...

journal_title：Biopolymers

authors： Rothemund S,Krause E,Beyermann M,Bienert M,Sykes BD,Sönnichsen FD

更新日期：1996-08-01 00:00:00

abstract：:The formation mechanism of an alanine-based peptide has been studied by all-atom molecular dynamics simulations with a recently developed all-atom point-charge force field and the Generalize Born continuum solvent model at an effective salt concentration of 0.2M. Thirty-two simulations were conducted. Each simulation ...

journal_title：Biopolymers

authors： Chowdhury S,Zhang W,Wu C,Xiong G,Duan Y

更新日期：2003-01-01 00:00:00

abstract：:Peptides represent a rich natural source of potential medicines with one notable pharmaceutical limitation being their relatively short duration of action. A particularly good example of this phenomenon is glucagon-like peptide 1 (GLP), a hormone of appreciable interest for the treatment of type II diabetes. In the na...

journal_title：Biopolymers

authors： De A,DiMarchi RD

更新日期：2010-01-01 00:00:00

abstract：:Chiral interaction of helical peptide with chiral molecule, and concomitant induction in its helix sense have been demonstrated in optically inactive nonapeptide (1) possessing Gly at its N-terminus: H-Gly-(Delta(Z)Phe-Aib)(4)-OCH(3) (1: Delta(Z)Phe = Z-dehydrophenylalanine; Aib = alpha-aminoisobutyric acid). Spectros...

journal_title：Biopolymers

authors： Ousaka N,Inai Y,Okabe T

更新日期：2006-11-01 00:00:00

abstract：:Recombinant murine amelogenins M179 and M166 were expressed in Escherichia coli and purified. The aggregation properties of these amelogenins have been investigated in aqueous solutions as well as acetonitrile-containing solutions using dynamic light scattering. Dynamic light scattering provides direct measurement of ...

journal_title：Biopolymers

authors： Moradian-Oldak J,Simmer JP,Lau EC,Sarte PE,Slavkin HC,Fincham AG

更新日期：1994-10-01 00:00:00

abstract：:The IR data for the R1 CO-O-CHR2 -CO-NHR3 derivatives are interpreted in terms of a H…π interaction involving the NH bond and the π orbitals of the ester function and giving rise to a high ν(CO) frequency and a low ν frequency. The resulting molecular conformation corresponds to the angular values ϕ # -90°, ψ # 0°. ...

journal_title：Biopolymers

authors： Boussard G,Marraud M

更新日期：1981-01-01 00:00:00

abstract：:Disintegrins, small molecular weight proteins contained in the venom of vipers and rattlesnakes, are high-affinity and selectivity integrin antagonists. Disintegrins inhibitory epitope mainly consists in a tripeptide sequence localized in a mobile loop protruding from the protein core. RTS and/or KTS tripeptide charac...

journal_title：Biopolymers

authors： Calvanese L,Falcigno L,D'Auria G

更新日期：2015-03-01 00:00:00

abstract：:A suite of FORTRAN programs, PREF, is described for calculating preference functions from the data base of known protein structures and for comparing smoothed profiles of sequence-dependent preferences in proteins of unknown structure. Amino acid preferences for a secondary structure are considered as functions of a s...

journal_title：Biopolymers

authors： Juretić D,Lee B,Trinajstić N,Williams RW

更新日期：1993-02-01 00:00:00

abstract：:Peptomers are oligomeric molecules composed of both α-amino acids and N-substituted glycine monomers, thus creating a hybrid of peptide and peptoid units. Peptomers have been used in several applications such as antimicrobials, protease inhibitors, and antibody mimics. Despite the considerable promise of peptomers as ...

journal_title：Biopolymers

authors： Butterfoss GL,Drew K,Renfrew PD,Kirshenbaum K,Bonneau R

更新日期：2014-09-01 00:00:00

abstract：:Suppressors of Cytokine Signaling (SOCS) proteins are negative regulators of JAK proteins that are receptor-associated tyrosine kinases, which play key roles in the phosphorylation and subsequent activation of several transcription factors named STATs. Unlike the other SOCS proteins, SOCS1 and 3 show, in the N-termina...

journal_title：Biopolymers

authors： La Manna S,Lopez-Sanz L,Leone M,Brandi P,Scognamiglio PL,Morelli G,Novellino E,Gomez-Guerrero C,Marasco D

更新日期：2017-11-20 00:00:00

abstract：:This work theoretically investigates the mechanical properties of a novel silk-derived biopolymer as polymerized in silico from sericin and elastin-like monomers. Molecular Dynamics simulations and Steered Molecular Dynamics were the principal computational methods used, the latter of which applies an external force o...

journal_title：Biopolymers

authors： Golas EI,Czaplewski C

更新日期：2014-09-01 00:00:00

abstract：:The design, synthesis, and evaluation of a novel series of receptors for protein surface recognition are described. The design of these agents is based around the attachment of four constrained peptide loops onto a central calix[4]arene scaffold. This arrangement mimics the role of the hypervariable loops in antibody ...

journal_title：Biopolymers

authors： Lin Q,Park HS,Hamuro Y,Lee CS,Hamilton AD

更新日期：1998-01-01 00:00:00

abstract：:In our continuing series of measurements of the complex index of refraction for representative samples of biological materials, we measured ovalbumin (egg albumin) over the spectral region from 0.130 (76,923 cm(-1)) to 2.50 microm (4000 cm(-1)). Films of ovalbumin suitable for optical analyses were prepared and measur...

journal_title：Biopolymers

authors： Arakawa ET,Tuminello PS,Khare BN,Milham ME

更新日期：2001-01-01 00:00:00

abstract：:Two-dimensional nmr spectra [correlated spectroscopy (COSY), homonuclear Hartmann-Hahn (HOHAHA), nuclear Overhauser effect spectroscopy (NOESY)] have been observed for cross-linked lysozyme, a chemically modified lysozyme derivative with an extra ester cross-link between residues E35 and W108. Eight shifted cross-peak...

journal_title：Biopolymers

authors： Noda Y,Fukuda Y,Segawa S

更新日期：1997-02-01 00:00:00

abstract：:Antagonism of the calcitonin gene-related peptide (CGRP) receptor may be a useful approach for migraine treatment. Selective PEGylated peptide antagonists to the CGRP receptor are described, derived from CGRP(8-37) with polymer derivatization at an engineered lysine-25 residue. Potent PEGylated peptides with improved ...

journal_title：Biopolymers

authors： Miranda LP,Shi L,Holder JR,Wright M,Gegg CV,Johnson E,Wild K,Stenkilsson M,Doellgast G,Manning BH,Salyers K

更新日期：2013-07-01 00:00:00

abstract：:Our previous studies of the potential utility of the C(alpha)D(alpha) stretch frequency, nu(CD), as a tool for determining conformation in peptide systems (Mirkin and Krimm, J Phys Chem A 2004, 108, 10923-10924; 2007, 111, 5300-5303) dealt with the spectroscopic characteristics of isolated alanine peptides with alpha(...

journal_title：Biopolymers

authors： Mirkin NG,Krimm S

更新日期：2009-09-01 00:00:00

abstract：:In Monte Carlo simulations of polymeric chains, the chains are most often represented as spheres, or cylinders with flat ends. In this methodological paper, we adopt a representation of the chains as spherocylinders (continuous cylinders ending in semispheres). With such a representation the testing for chain overlap,...

journal_title：Biopolymers

authors： Yeramian E,Schaeffer F,Caudron B,Claverie P,Buc H

更新日期：1989-12-01 00:00:00

abstract：:G protein-coupled receptor kinase 2 (GRK2) plays a central role in the cellular transduction network. In particular, during chronic heart failure GRK2 is upregulated and believed to contribute to disease progression. Thereby, its inhibition offers a potential therapeutic solution to several pathological conditions. In...

journal_title：Biopolymers

authors： Gomez-Monterrey I,Carotenuto A,Cipolletta E,Sala M,Vernieri E,Limatola A,Bertamino A,Musella S,Grieco P,Trimarco B,Novellino E,Iaccarino G,Campiglia P

更新日期：2014-01-01 00:00:00

abstract：:The natural amino acids are primarily helix breakers at the low assignment temperatures characteristic of many studies, but recent genomic analyses of thermophilic proteins suggest that at high temperatures, some breakers may become strong helix formers. Moreover, the breaker/former inventory has not been previously c...

journal_title：Biopolymers

authors： Nasr KA,Schubert CR,Török M,Kennedy RJ,Kemp DS

更新日期：2009-05-01 00:00:00

abstract：:The open reading frame 4 (ORF 4) gene product of barley yellow dwarf virus (BYDV) may act as a movement protein (MP) by assisting the transport of viral genomic RNA across the nuclear envelope (NE) of host plant cells. To investigate interactions between BYDV MP and the NE, wild-type and mutant open reading frame (ORF...

journal_title：Biopolymers

authors： Liu K,Xia Z,Zhang Y,Wen Y,Wang D,Brandenburg K,Harris F,Phoenix DA

更新日期：2005-10-05 00:00:00

abstract：:The spectroscopic properties of syringomycin E, an antibiotic lipodepsinonapeptide associated with pathological states in plants, have been investigated by uv absorbance and CD spectroscopies, and by the synthesis of relevant model compounds. Initial studies [E. Vaillo, A. Ballio, P. L. Luisi, and R. M. Thomas (1990) ...

journal_title：Biopolymers

authors： Vaillo E,Ballio A,Luisi PL,Thomas RM

更新日期：1992-10-01 00:00:00

abstract：:Partially acetylated, high molecular weight glucuronans were produced by a Sinorhizobium meliloti mutant strain. Two native glucuronan samples with various degrees of acetylation were sonicated to obtain lower molecular weight samples and with low viscosity suitable for chemical modification and (13)C NMR experiments....

journal_title：Biopolymers

authors： Pau-Roblot C,Petit E,Sarazin C,Courtois J,Courtois B,Barbotin JN,Séguin JP

更新日期：2002-06-01 00:00:00

abstract：:To obtain information about the structure-activity relationships of analgesic peptides, we modified the previously reported tripeptide, H-Lys-Pro-Thr-OH (C). The proline part in C was replaced with various analogues of unconventional amino acids [(3aS, 7aS)-octahydroindole-2-carboxylic acid (Oic), (S,S,S,)-2-azabicicl...

journal_title：Biopolymers

authors： Caliendo G,Greco G,Grieco P,Perissutti E,Santagada V,Ialenti A,Maffia P,Albrizio S,Santini A

更新日期：1996-01-01 00:00:00

abstract：:To investigate the mechanism leading to the reduction in tensile strength of permanent waved human hair, the structure of cross-sections at various depths of permanent waved white human hair was directly analyzed without isolating the cuticle and cortex, using Raman spectroscopy. The beta-sheet and/or random coil cont...

journal_title：Biopolymers

authors： Kuzuhara A

更新日期：2007-02-15 00:00:00