A probiotic approach to caries management.

Abstract:

:The surgical approach has been the predominate mode of caries management for the past 150 years. Dentistry has, however, in recent years moved toward an antibiotic/antimicrobial model of disease management. This approach, however, raises serious questions: (1) do the antibiotic/antimicrobial agents (chlorhexidine, povidone iodine, fluoride, etc) kill all offending organisms?; (2) if so, do the agents preclude the re-entry of the same organisms from external sources?; and (3) if the agents do kill all the offending organisms, do any remaining pathogenic organisms have selective advantage in repopulating the tooth surfaces? To overcome the problems inherent in an antibiotic/antimicrobial approach, probiotic methods are currently under study as means of caries management. This paper discusses probiotic approaches, such as genetically modified Streptococcus mutans and targeted antimicrobials in the management of dental caries. Implications for this approach in the management of other diseases are also presented.

journal_name

Pediatr Dent

journal_title

Pediatric dentistry

authors

Anderson MH,Shi W

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

151-3; discussion 192-8

issue

2

eissn

0164-1263

issn

1942-5473

journal_volume

28

pub_type

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