[How much primaquine is needed to eradicate Plasmodium vivax hypnozoites?].

Abstract:

INTRODUCTION:Primaquine is now the only drug available to eradicate Plasmodium vivax malaria. The optimal dose of primaquine to prevent relapses of P. vivax remains under discussion. CLINICAL CASES:We describe three cases of P. vivax malaria from different geographical areas, in which a tolerance to standard doses of primaquine and, in some cases, to much higher doses has been observed. COMMENTS:P. vivax tolerance to primaquine is an emerging problem in daily practice. Reassessment of the primaquine dose required to eradicate P. vivax intrahepatic hypnozoites is needed.

authors

Muñoz J,Velasco M,Alonso D,Valls ME,Corachán M,Gascón J

doi

10.1157/13083372

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

29-30

issue

1

eissn

0213-005X

issn

1578-1852

pii

13083372

journal_volume

24

pub_type

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