[Etravirine in clinical practice: Experience in 151 non-naïve patients].

Abstract:

BACKGROUND:There are limited data on etravirine (ETV) use in routine clinical practice. METHODS:The reasons, efficacy and tolerability of its use are retrospectively reviewed. RESULTS:Overall, 151patients started a regimen containing ETV. The main reasons for prescription were toxicity and virological failure. After a median follow-up of 16months 76.2% of the patients had an undetectable viral load. Patients with detectable HIV-RNA at baseline had a greater risk of failure (31.7% vs 18%; P=.05). CONCLUSION:ETV is safe, effective and durable.

authors

Valencia Ortega ME,Moreno Celda V,Ramírez-Olivencia G,Martín Carbonero L

doi

10.1016/j.eimc.2013.04.018

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

669-71

issue

10

eissn

0213-005X

issn

1578-1852

pii

S0213-005X(13)00138-9

journal_volume

31

pub_type

杂志文章
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    doi:

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    authors: Molina JM,Córdoba J,Ramírez P,Gobernado M

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  • [Meningococcal infection caused by Neisseria meningitidis serogroup C].

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    pub_type: 杂志文章

    doi:

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    pub_type: 杂志文章

    doi:

    authors: Pintor E,Piret MV,Velasco M,Barreiro P,Ruiz M,Blanco J

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    pub_type: 杂志文章,多中心研究

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    abstract::Although the WHO original target date for the global eradication of poliomyelitis was the year 2000 -thanks to vaccination and institutional, public and private, resources for that purpose-, in 2013 the disease remained endemic in three countries, Afghanistan, Pakistan and Nigeria, and some cases were described in fiv...

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    pub_type: 杂志文章,评审

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    authors: López-Cortés LF

    更新日期:2008-12-01 00:00:00

  • [Francisella tularensis: update on microbiological diagnosis after an epidemic outbreak].

    abstract:AIMS:Francisella tularensis is a facultative intracellular gramnegative aerobic coccobacilli which is difficult to isolate. The appearance of an epidemic outbreak of tularemia in Castilla y Leon (Spain) during the first months of 1998 led bur microbiology laboratory to develop the diagnostic methods of this disease whi...

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    pub_type: 杂志文章

    doi:

    authors: Labayru C,Palop A,López-Urrutia L,Avellaneda C,Mazón MA,Alberte A,Pascual PP

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    doi:

    authors: Guerrero A,Quereda C,Escudero R,Cobo J,Morcillo R,Martí-Belda P

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  • In vitro activity of echinocandins against non-Candida albicans: is echinocandin antifungal activity the same?

    abstract::The echinocandins anidulafungin, caspofungin, and micafungin have a broad and similar spectrum of in vitro and in vivo activity against most Candida spp. Minimal inhibitory concentrations (MICs) for Candida spp. are usually below 1 μg/mL for most isolates. The exceptions are Candidaparapsilosis and C. guilliermondii. ...

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    abstract::Because lifelong therapy is needed in HIV infection, high long-term adherence is necessary. Darunavir/co-bicistat/emtricitabina/tenofovir alafenamide (Symtuza®) is the first triple therapy combining a protease inhibitor (PI) in a single tablet regimen. This drug combines the potency and high genetic barrier of the mos...

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  • [Spanish recommendations for proper use of enfuvirtide].

    abstract::Enfuvirtide is a high-cost, parenterally administered drug commonly used in late phases of HIV infection, when its efficacy may be compromised. To optimize enfuvirtide use, consensus recommendations for this purpose have been formulated by 247 physicians attending patients with HIV infection in Spain. A literature rev...

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    abstract::The development of an antimicrobial stewardship program (ASP) requires institutional support. However, obtaining sufficient institutional support is often a complex task that requires convincing the hospital's managers of the benefits of these programs. Additionally, in the design and implementation of an ASP, antimic...

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  • [Human immunodeficiency virus-infected patients with community-acquired pneumonia: implication of respiratory viruses].

    abstract::The role of respiratory viruses in community-acquired pneumonia (CAP) in human immunodeficiency virus (HIV)-infected patients has not been extensively investigated. The objective was to study the implication of respiratory viruses in HIV patients with CAP, through a prospective, three-year study in a third-level hospi...

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    更新日期:2008-02-01 00:00:00