Abstract:
OBJECTIVES:To describe: 1) the main features of antimicrobial stewardship activities (ASA) in Spanish hospitals and 2) the perceptions of the Spanish Infectious Diseases (ID) community on ASA. METHODS:An online survey was designed and distributed through the e-mailing lists of several working groups of the Spanish Clinical Microbiology and Infectious Diseases Society. RESULTS:Between September 15 and November 23, 2009, surveys representing 78 hospitals were received. Most of the respondents were either ID physicians (30%) or microbiologists (29%), and 31/78 hospitals (40%) had ongoing ASA. These hospitals were concentrated in 4 of the 17 regions, particularly in Catalonia. Professionals belonging to 26/31 centres with ASA completed the survey. The most frequent principles of antibiotic (ABX) stewardship implemented in these programs were: 1) ABX streamlining (22/26) and 2) intravenous to oral switch (22/26) followed by 3) strategic monitoring of ABX (21/26). In 22/26 (86%) of the centres with ASA any physician could initially prescribe any of the antimicrobials included in the formulary. The most frequent activity carried out was ABX restriction, 69% (18/26) followed by conferences 61% (16/26) and therapeutic audit and feed-back 54% (14/26). When asked which antimicrobials that should be closely monitored, carbapenems were considered by all respondents in centres with ongoing ASA. CONCLUSIONS:1) A minority (40%) of the surveyed hospitals in Spain has an ongoing ASA and large geographical variations were observed. 2) ASA were most commonly structured in the form of an integrated part-time multidisciplinary team of ID physicians and Pharmacists, and 3) Carbapenems were considered the ABX most required to be monitored.
journal_name
Enferm Infecc Microbiol Clinjournal_title
Enfermedades infecciosas y microbiologia clinicaauthors
Paño-Pardo JR,Padilla B,Romero-Gómez MP,Moreno-Ramos F,Rico-Nieto A,Mora-Rillo M,Horcajada JP,Ramón Arribas J,Rodríguez-Baño Jdoi
10.1016/j.eimc.2010.05.005subject
Has Abstractpub_date
2011-01-01 00:00:00pages
19-25issue
1eissn
0213-005Xissn
1578-1852pii
S0213-005X(10)00397-6journal_volume
29pub_type
杂志文章,多中心研究abstract::One hundred and seven Shigella spp. strains were isolated in our laboratory during the years 2000 to 2010. One Shigella sonnei harboured the genes that coded the β-lactamases TEM-1 and CTX-M-15, identifying the structure, ISEcp1+bla(CTX-M-15)+orf477, in their genetic environment. The strain also carried a class 2 inte...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
doi:10.1016/j.eimc.2011.11.015
更新日期:2012-10-01 00:00:00
abstract::Dental implant-associated infections are expected to be increasingly more common as the number of patients with implants for more than 10 years rises. There are 2 stages of peri-implant infection: early mucositis, consisting of inflammation of the peri-implant soft tissues without loss of supporting bone, and a more a...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
doi:10.1157/13128277
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abstract:INTRODUCTION:Vancomycin-resistant enterococci (VRE) among haemodialysis patients has increased rapidly and, to date, there is no report of this incidence in Portugal. METHODS:A total of 121 faecal samples were collected from haemodialysis patients, and then tested for VRE. Antimicrobial resistance, virulence and multi...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
doi:10.1016/j.eimc.2013.09.001
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:In order to study the evolution of the outbreak that occurred between 2009 and 2010 in 3 hospitals in Zaragoza, all vancomycin-resistant clinical Enterococcus faecalis isolates identified between 2011 and 2013 at these hospitals were characterised. METHODS:Molecular characterisation of the isolates and an...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.eimc.2016.02.020
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abstract::The disadvantages of the long-term administration of antiretroviral therapy as well as the huge number of affected persons have placed the cure of HIV as a primary goal of Public Health. HIV may persist in the organism by at least four mechanisms: a latently infected cellular reservoir, the persistent replication of H...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
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更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION:Nosocomial fungal infections have increased significantly in the last decade. Candida detection in clinical specimens can mean either colonization or an infection which can be local (muguet) or invasive. Knowledge of the species helps in choosing the best treatment. The aims of this study were to determine...
journal_title:Enfermedades infecciosas y microbiologia clinica
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doi:10.1016/j.eimc.2012.09.011
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abstract:OBJECTIVE:To study the possible viral etiology in 139 infants with lower respiratory tract infection who required hospitalization in the Infant Unit of our hospital, from October 1994 to June 1995. PATIENTS AND METHODS:139 patients were admitted, aged from 13 days to 14 months, during this period. The etiological agen...
journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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abstract::Because lifelong therapy is needed in HIV infection, high long-term adherence is necessary. Darunavir/co-bicistat/emtricitabina/tenofovir alafenamide (Symtuza®) is the first triple therapy combining a protease inhibitor (PI) in a single tablet regimen. This drug combines the potency and high genetic barrier of the mos...
journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,实务指引
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abstract:BACKGROUND:Streptococcus pyogenes is a bacteria which, at present, is seldom isolated in blood and articular fluid. An intravenous drug addict with human immunodeficiency virus infection, with bacteremia and arthritis by S. pyogenes, associated with tuberculosis is presented. METHODS:Blood and articular fluid cultures...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
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abstract:INTRODUCTION:Citrus hystrix is widely used by Indonesians as a traditional medicine for gastrointestinal diseases, including Salmonella spp. infection. We investigated the antibacterial activity of the ethanolic peel extract of C. hystrix against Salmonella typhimurium. METHODS:The antibacterial activity was evaluated...
journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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更新日期:2010-11-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 临床试验,杂志文章,多中心研究
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abstract:BACKGROUND:The evaluation of health care workers role in methicillin-resistant Staphylococcus aureus outbreaks and the efficacy of mupirocin as a topical agent for nasal carriers. METHOD:Microbiologic study of nasal microflora of 1547 health care workers from the San Carlos University Hospital and 108 health care work...
journal_title:Enfermedades infecciosas y microbiologia clinica
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doi:
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,多中心研究
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
doi:
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journal_title:Enfermedades infecciosas y microbiologia clinica
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abstract::Intestinal invagination is rather frequently associated with local tumors, adenovirus infections, and occasionally with Yersinia enterocolitica. However, in many cases the etiology is not known. We have studied 88 children with intestinal invagination in whom cellular cultures of Hep 2 and pulmonary fibroblasts of hum...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
doi:
更新日期:1990-08-01 00:00:00
abstract::Chronic hepatitis B continues to be a serious problem worldwide. Because a high viral load is associated with greater progression to cirrhosis and hepatocarcinoma in these patients, new drugs that achieve rapid, potent and lasting suppression of viral replication must be sought. Entecavir is a new, highly potent antiv...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
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更新日期:2008-05-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
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abstract:INTRODUCTION:Zika virus is mainly transmitted through the bites of infected Aedes mosquitoes, although mother-to-child and sexual transmission have also been described. The presence of Zika virus in semen after infection seems to be not uncommon, but the duration of viral persistence has not been well-determined. METH...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
abstract::Mucormycosis is a rare opportunistic fungal infection of immunosuppressed patients. We describe here 5 cases of mucormycosis: three with facial and eye involvement, one with lung involvement and one affecting skin and joints. All five patients had underlying diseases: diabetes, leukemia, lymphoma, neoplasia and AIDS. ...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::The diffusion of hepatitis B virus was investigated in an open institution for mentally retarded patients, where 24 patients with Down's syndrome (DS) and 94 with other types of mental retardation (OMR) were being cared for. The immunogenic response to a recombinant vaccine intramuscularly injected to the deltoid musc...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00