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Orthogonal polarization spectral (OPS) imaging and topographical characteristics of oral squamous cell carcinoma.

Abstract：

:Tumor microcirculatory characteristics until now have only been assessed by histological examination of biopsies or invasive imaging technique. The recent introduction of orthogonal polarization spectral (OPS) imaging as a new tool for in vivo visualization of human microcirculation makes it possible to acquire high resolution images of the oral mucosa. In this study we report the microcirculatory changes in ten patients with oral squamous cell carcinoma of the tongue and compared the images to the normal contralateral side as the control. All carcinomas were T2 tumors without evidence for lymph node metastasis. The carcinomas were characterized by chaotic and dilated vessels accompanied by numerous areas of haemorrhage. The OPS technique seems very promising in the assessment of oral squamous cell carcinoma microcirculatory characteristics and may possibly play a future role in both the detection of early oral mucosal vascular aberrations and the effect of anti-tumor agents on the tumor microvasculature.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Lindeboom JA,Mathura KR,Ince C

doi

10.1016/j.oraloncology.2005.10.014

subject

Has Abstract

pub_date

2006-07-01 00:00:00

pages

581-5

issue

6

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(05)00297-6

journal_volume

42

pub_type

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