Type I and III collagen degradation products in serum predict patient survival in head and neck squamous cell carcinoma.

abstract：:Carboplatin (CBDCA) alone or in combination with irradiation and other chemotherapeutic agents has been used for the treatment of oral squamous carcinoma. However, there are some limitations for such therapy because of inherent or acquired resistance to CBDCA. To gain some insights into the association of CBDCA resist...

journal_title：Oral oncology

authors： Noutomi T,Chiba H,Itoh M,Toyota H,Mizuguchi J

更新日期：2002-01-01 00:00:00

abstract：:Head and neck cancers during pregnancy are rising in incidence. Clinicians need to be aware of the principles of managing these cases. This paper is a review of the literature of head and neck cancers during pregnancy with a short case series of six non-thyroid pregnancy-associated cancers treated by a head and neck o...

journal_title：Oral oncology

authors： Atabo A,Bradley PJ

更新日期：2008-03-01 00:00:00

abstract：:Patients with HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are significantly different with regard to sociodemographic and behavioral characteristics that clinicians may use to assume tumor HPV status. Machine learning methods were used to evaluate the predictive value of patient charact...

journal_title：Oral oncology

authors： D'Souza G,Zhang HH,D'Souza WD,Meyer RR,Gillison ML

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the role of the extended Abbé flap in the reconstruction of complex midfacial defects (upper lip, nasal base and medial cheek). We describe our personal experience with this method and present some interesting aspects from the relevant literature. MATERIALS AND METHO...

journal_title：Oral oncology

authors： Mantsopoulos K,Iro H,Constantinidis J

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:The advantages of the circulating cell-free DNA (cfDNA) methodology are quick results and the possibility of repeated analysis. The main aim of our study was to establish the relationship of the total cfDNA with patients' clinical characteristics and circulating HPV DNA detection in the blood of patients wit...

journal_title：Oral oncology

authors： Mazurek AM,Rutkowski T,Fiszer-Kierzkowska A,Małusecka E,Składowski K

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:Cancer immunoediting represents a relatively novel concept attempting to explain the process of tumor escape from the host immune system response. Here, we attempted to elucidate the role of programmed death ligand 1 (PD-L1), the tumor microenvironment, and tumor escape mechanisms that allow malignant transf...

journal_title：Oral oncology

authors： Yagyuu T,Hatakeyama K,Imada M,Kurihara M,Matsusue Y,Yamamoto K,Obayashi C,Kirita T

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:The function of NOTCH signaling (oncogenic or oncosuppressive) remains controversial in head and neck squamous cell carcinomas (HNSCC). The purpose of this work is to investigate the role of NOTCH pathway in HNSCC prognosis. METHODS:Immunohistochemical NOTCH1 and HES1 expression was jointly evaluated and co...

journal_title：Oral oncology

authors： Grilli G,Hermida-Prado F,Álvarez-Fernández M,Allonca E,Álvarez-González M,Astudillo A,Moreno-Bueno G,Cano A,García-Pedrero JM,Rodrigo JP

更新日期：2020-11-01 00:00:00

abstract：:This report describes highlights the dramatic responses seen in patients who were given paclitaxel post progression on immunotherapy. There are multiple mechanisms by which synergistic effects of immunotherapy and chemotherapy occur. Further prospective studies on chemotherapy and immunotherapy are eagerly awaited. ...

journal_title：Oral oncology

authors： Sukari A,Nagasaka M,Abdallah N

更新日期：2018-05-01 00:00:00

abstract：:Pemetrexed has been evaluated as a novel chemotherapeutic for head and neck cancer (HNC). In this review, we examined the efficacy and tolerability of pemetrexed in patients with HNC. Relevant English-language literature was identified via PubMed and a review of published abstracts from the American Society of Clinica...

journal_title：Oral oncology

authors： Argiris A,Pennella E,Koustenis A,Hossain AM,Obasaju CK

更新日期：2013-06-01 00:00:00

abstract：:The aim of this study was to integrate the available data published on odontogenic carcinosarcoma into a comprehensive analysis of their features, treatment and recurrence. An electronic search with no publication date or language restriction was undertaken in March 2018 in the following databases: Medline Ovid, PubMe...

journal_title：Oral oncology

authors： Schuch LF,de Arruda JAA,Silva LVO,Abreu LG,Silva TA,Mesquita RA

更新日期：2018-10-01 00:00:00

abstract：:This systematic review gives an extensive overview of the current state of functional imaging during (chemo)radiotherapy to predict locoregional control (LRC) and overall survival (OS) for head and neck squamous cell carcinoma. MEDLINE and EMBASE were searched for literature until April 2018 assessing the predictive p...

journal_title：Oral oncology

authors： Martens RM,Noij DP,Ali M,Koopman T,Marcus JT,Vergeer MR,de Vet H,de Jong MC,Leemans CR,Hoekstra OS,de Bree R,de Graaf P,Boellaard R,Castelijns JA

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate whether texture features extracted from 18F-FDG PET/CT images may provide additional prognostic information in patients with metastatic nasopharyngeal carcinoma (NPC). MATERIALS AND METHOD:We retrospectively examined 52 patients with metastatic NPC who underwent ass...

journal_title：Oral oncology

authors： Lin HC,Chan SC,Cheng NM,Liao CT,Hsu CL,Wang HM,Lin CY,Chang JT,Ng SH,Yang LY,Yen TC

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:We assess the incremental cost-effectiveness ratio (ICER) of the oral cancer (OC) screening program in Taiwan. MATERIALS AND METHODS:We interlinked the Cancer Registry, Mortality Registry, National Vital Statistics, reimbursement database of National Health Insurance, and the National Oral Cancer Screening ...

journal_title：Oral oncology

authors： Huang CC,Lin CN,Chung CH,Hwang JS,Tsai ST,Wang JD

更新日期：2019-02-01 00:00:00

abstract：:Head and neck squamous cell cancer (HNSCC) is the sixth most common cancer in the world. Effective therapeutic modalities such as surgery, radiation, chemotherapy and combinations of each are used in the management of this disease. Efforts are ongoing throughout the world to improve early detection and prevention of H...

journal_title：Oral oncology

authors： Sayed SI,Dwivedi RC,Katna R,Garg A,Pathak KA,Nutting CM,Rhys-Evans P,Harrington KJ,Kazi R

更新日期：2011-04-01 00:00:00

abstract：:In loco-regionally advanced head and neck squamous cell cancer (HNSCC), concurrent 3-weekly cisplatin improves overall survival (OS) compared to radiotherapy alone, but is often associated with renal toxicity. The use of radiotherapy with accelerated fractionation schedules has been reported to improve survival but it...

journal_title：Oral oncology

authors： Espeli V,Zucca E,Ghielmini M,Giannini O,Salatino A,Martucci F,Richetti A

更新日期：2012-03-01 00:00:00

abstract：:We demonstrated the accumulation of CD11b(high)Gr-1(+) cells in a murine model of squamous cell carcinoma (SCC). Inoculation of NR-S1K cells derived from oral SCC induced a rapid and clear accumulation of CD11b(high)Gr-1(+) cells in secondary lymphoid organs as well as in peripheral blood. Phenotypic and morphological...

journal_title：Oral oncology

authors： Tanaka K,Jinhua P,Omura K,Azuma M

更新日期：2007-07-01 00:00:00

abstract：:Hepatoma-derived growth factor (HDGF) participates in oncogenic progression and represents a prognostic factor in several types of cancer. This study aimed to elucidate the role of HDGF during oral carcinogenesis. HDGF expression and the tumorigenic behaviors in human oral cell lines were investigated by immunoblottin...

journal_title：Oral oncology

authors： Lin YW,Li CF,Chen HY,Yen CY,Lin LC,Huang CC,Huang HY,Wu PC,Chen CH,Chen SC,Tai MH

更新日期：2012-07-01 00:00:00

abstract：:Verrucous carcinomas are considered to have poor radioresponsiveness and radiotherapy has been reported to induce anaplastic transformation. Surgery has been considered to be the primary mode of treatment for these tumours. The clinical features, response to radiotherapy, survival and prognostic factors of a group of ...

journal_title：Oral oncology

authors： Jyothirmayi R,Sankaranarayanan R,Varghese C,Jacob R,Nair MK

更新日期：1997-03-01 00:00:00

abstract：:Metallothioneins (MTs) are a family of low molecular weight, cysteine-rich, inducible, intracellular proteins that bind heavy metals with high affinity. MT-1 is known as a stress-inducible protein and functions as an antioxidant enzyme. Areca quid chewing is a major risk factor in the development and further progressi...

journal_title：Oral oncology

authors： Lee SS,Yang SF,Ho YC,Tsai CH,Chang YC

更新日期：2008-02-01 00:00:00

abstract：:In our previous study, we established an in vitro cellular carcinogenesis model of oral squamous cell carcinoma (OSCC), including a human immortalized oral epithelial cell (HIOEC) and a cancerous cell line (HB96). Microarray analysis showed that the gene encoding Yes-associated protein (YAP) was significantly increase...

journal_title：Oral oncology

authors： Zhang L,Ye DX,Pan HY,Wei KJ,Wang LZ,Wang XD,Shen GF,Zhang ZY

更新日期：2011-08-01 00:00:00

abstract：:The selection of housekeeping genes is critical for gene expression studies. To address this issue, four candidate housekeeping genes, including several commonly used ones, were investigated in oral squamous cell carcinoma cell lines. A simple quantitative RT-PCR approach was employed by comparing relative expression ...

journal_title：Oral oncology

authors： Campos MS,Rodini CO,Pinto-Júnior DS,Nunes FD

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The chemokine receptor CCR7 is expressed on lymphocytes and dendritic cells and is responsible for trafficking of these cells in and out of secondary lymphoid organs. It has recently been shown that CCR7 expression is elevated in a number of cancers, including head and neck cancers, and that its expression c...

journal_title：Oral oncology

authors： Basheer HA,Pakanavicius E,Cooper PA,Shnyder SD,Martin L,Hunter KD,Vinader V,Afarinkia K

更新日期：2018-05-01 00:00:00

abstract：:This review aims at simplifying the relevant imaging anatomy, guiding the optimal imaging method and highlighting the key imaging findings that influence prognosis and management of oral cavity squamous cell carcinoma (OSCC). Early OSCC can be treated with either surgery alone while advanced cancers are treated with a...

journal_title：Oral oncology

authors： Mahajan A,Ahuja A,Sable N,Stambuk HE

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Given the propensity for HPV-positive head and neck squamous cell carcinoma (HPV-HNSCC) to metastasize to cervical lymph nodes, fine needle aspiration (FNA) plays an important diagnostic role in their initial detection. Indeed, there is now an unwavering commitment to HPV testing of FNAs even in the absence ...

journal_title：Oral oncology

authors： El-Salem F,Mansour M,Gitman M,Miles BA,Posner MR,Bakst RL,Genden EM,Westra WH

更新日期：2019-03-01 00:00:00

abstract：:Health-related quality of life (HRQoL) is a subjective measure of patients' experience of disease and treatment. We systematically reviewed the literature to identify high quality manuscripts reporting HRQoL outcomes in adults with squamous cell carcinoma of the head and neck (HNSCC) treated with an organ-sparing cura...

journal_title：Oral oncology

authors： Klein J,Livergant J,Ringash J

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Oral mucositis is a major event increasing treatment costs of head and neck squamous cell carcinoma (HNSCC) patients treated with chemoradiation (CRT). This study was designed to estimate the cost-effectiveness of low-level laser therapy (LLLT) to prevent oral mucositis in HNSCC patients receiving CRT. METH...

journal_title：Oral oncology

authors： Antunes HS,Schluckebier LF,Herchenhorn D,Small IA,Araújo CM,Viégas CM,Rampini MP,Ferreira EM,Dias FL,Teich V,Teich N,Ferreira CG

更新日期：2016-01-01 00:00:00

abstract：:To understand the role of 70 kDa heat shock protein (HSP70) in the pathogenesis of oral cancer, its expression was studied in human normal, premalignant and malignant oral mucosa. Cell surface expression of HSP70 was assessed in oral tissue specimens by flow cytometric analysis using a mouse monoclonal antibody agains...

journal_title：Oral oncology

authors： Kaur J,Das SN,Srivastava A,Ralhan R

更新日期：1998-03-01 00:00:00

abstract：:Oral mucositis (OM) is a devasting toxicity associated with cytotoxic cancer therapy. Antrum mucosal protein (AMP)-18 and a synthetic peptide surrogate, exhibit cell protective and mitogenic properties in in vitro and in vivo models of gastrointestinal epithelial cell injury. The mucosal barrier-protective effects may...

journal_title：Oral oncology

authors： Chen P,Lingen M,Sonis ST,Walsh-Reitz MM,Toback FG

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:Recent preclinical research has renewed interest in the interplay between glucose dysregulation and cancer. Metformin holds promise as an adjunctive antineoplastic agent in head and neck cancer (HNC). We aimed to explore the impact of metformin in HNC patients from a population-based dataset. PATIENTS & MET...

journal_title：Oral oncology

authors： Stokes WA,Eguchi M,Amini A,Hararah MK,Ding D,McDermott JD,Bradley CJ,Karam SD

更新日期：2018-09-01 00:00:00

abstract：:The techniques of lymphatic mapping and sentinel node biopsy are finding increasing utility in the management of the loco-regional lymphatics in many areas of oncology. Our unit is currently investigating their feasibility in relation to the management of the clinically node negative neck in oral squamous cell carcino...

journal_title：Oral oncology

authors： Hyde NC,Prvulovich E,Keshtgar MR

更新日期：2002-12-01 00:00:00