当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis.

Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis.

Abstract：

OBJECTIVE:Recently, reports have indicated that the imbalance of circulating angiogenic factors is important in the onset of preeclampsia. In this study we investigated angiogenic factor levels in women with preeclampsia, preeclampsia superimposed on chronic glomerulonephritis, gestational proteinuria, and normal pregnancies. STUDY DESIGN:We measured several circulating angiogenic factors, placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase-1, and soluble fetal liver kinase-1. RESULTS:Compared with women with normal pregnancies, placental growth factor concentrations were lower, and soluble fms-like tyrosine kinase 1 concentrations were higher in women with preeclampsia and gestational proteinuria; soluble fms-like tyrosine kinase 1 concentrations were also higher in women with preeclampsia superimposed on chronic glomerulonephritis. CONCLUSION:There were obvious differences in the levels of circulating angiogenic factors placental growth factor and soluble fms-like tyrosine kinase 1 among preeclampsia, gestational proteinuria, and controls. The imbalance of angiogenic factors is important in the onset of preeclampsia superimposed on chronic glomerulonephritis.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Masuyama H,Suwaki N,Nakatsukasa H,Masumoto A,Tateishi Y,Hiramatrsu Y

doi

10.1016/j.ajog.2005.08.034

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

551-6

issue

2

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(05)01275-5

journal_volume

194

pub_type

杂志文章

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