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Nutritional aspects modulating brain development and the responses to stress in early neonatal life.

Abstract：

:Nutrition is one of the critical factors insuring adequate growth and development in all species. In particular, brain development is sensitive to specific nutrient intake such as proteins and lipids, which are important for cell membrane formation and myelinization. Carbohydrate intake insures adequate short-term energy supply, but has important effects on the activity of the hypothalamic-pituitary-adrenal (HPA) axis to regulate stress responsiveness. This review focuses on the effects of carbohydrates and fat on the activity of the HPA axis as well as other brain-related functions such as pain modulation, neuropeptide and neurotransmitters release, and some aspects related to cognitive functions. The role of leptin, DHA and AA as mediators of the effects of fat on the brain is discussed.

journal_name

Prog Neuropsychopharmacol Biol Psychiatry

journal_title

Progress in neuro-psychopharmacology & biological psychiatry

authors

Walker CD

doi

10.1016/j.pnpbp.2005.08.010

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

1249-63

issue

8

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(05)00273-3

journal_volume

29

pub_type

杂志文章,评审

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