Abstract:
:Microvolt T-wave alternans (TWA) testing involves measuring variation in the morphology of the T-wave on an every other beat basis. The magnitude of the variation observed is typically on the order of a few microvolts. Thus in order to detect microvolt TWA, specialized recording and signal processing methods must be employed for reliable measurement. Additionally, microvolt TWA is not generally present at rest even in patients at risk of ventricular tachyarrhythmias and therefore exercise stress, pharmacologic stress, or atrial pacing must be utilized in order to elevate the heart rate. A positive MTWA test is one in which sustained TWA is present with an onset heart rate < or = 110 bpm. With current instrumentation, microvolt TWA represents an inexpensive, convenient non-invasive testing modality. Microvolt TWA has been evaluated prospectively in a variety of patient populations as a means of predicting occurrence of ventricular tachyarrhythmic events and its association with the genesis of ventricular arrhythmias has been demonstrated. Future role of microvolt TWA testing in noninvasive risk stratification is awaiting results of ongoing clinical trials. In this article, we tried to review the techniques, interpretation, indications, clinical studies, and future perspectives of microvolt TWA.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Haghjoo M,Arya A,Sadr-Ameli MAdoi
10.1016/j.ijcard.2005.06.049subject
Has Abstractpub_date
2006-05-24 00:00:00pages
293-306issue
3eissn
0167-5273issn
1874-1754pii
S0167-5273(05)00880-6journal_volume
109pub_type
杂志文章,评审abstract:AIM:To evaluate the predictive role of hs-CRP and fibrinogen for cardio- and cerebrovascular events in a population of patients with type 2 diabetes. METHODS:We studied 156 patients with type 2 diabetes, mean age 66+10 years, and 156 sex and age matched control subjects. Patients underwent physical examination, EKG, m...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2004.12.051
更新日期:2006-01-04 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2012.12.002
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abstract:BACKGROUND:Conflicting results exist regarding the association between a common Haptoglobin (Hp) polymorphism and risk of coronary artery disease. We investigated the association of three functionally different anti-oxidant and anti-inflammatory Hp phenotypes (Hp1-1, Hp2-1, Hp2-2) with invasively measured degree and co...
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更新日期:2016-10-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.05.113
更新日期:2018-11-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2009-03-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.06.012
更新日期:2013-10-09 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.07.027
更新日期:2017-12-15 00:00:00
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pub_type: 杂志文章
doi:10.1016/0167-5273(88)90053-8
更新日期:1988-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-07-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(95)02460-e
更新日期:1995-11-24 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.11.196
更新日期:2017-01-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.01.032
更新日期:2007-01-31 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ijcard.2018.01.054
更新日期:2018-06-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(96)02853-7
更新日期:1997-01-31 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(90)90163-y
更新日期:1990-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.10.078
更新日期:2016-01-15 00:00:00
abstract::We describe an asymptomatic patient with multiple fistulae between coronary arteries and the main pulmonary artery with an insignificant left-to-right shunt. Possible embryological basis of this anomaly is discussed. ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(87)90274-9
更新日期:1987-07-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2017.02.126
更新日期:2017-08-15 00:00:00
abstract::Takotsubo cardiomyopathy is an increasingly reported syndrome characterized by transient apical left ventricular dysfunction in absence of flow limiting coronary artery disease. Prolongation of QT interval associated with Takotsubo cardiomyopathy has been previously reported in published case series but none of these ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.04.021
更新日期:2009-08-14 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.12.016
更新日期:2013-07-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(98)00014-x
更新日期:1998-04-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2019-08-15 00:00:00
abstract:BACKGROUND:Successful reperfusion of epicardial coronary arteries does not necessarily result in actual myocardial perfusion. Local intracoronary (IC) delivery of GP IIb/IIIa inhibitors (GPI) has been proposed to achieve further clinical efficacy when compared to standard intravenous (IV) administration. However clinic...
journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析
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更新日期:2013-09-30 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.03.051
更新日期:2013-10-03 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.05.033
更新日期:2018-11-15 00:00:00
abstract:BACKGROUND:Patent foramen ovale (PFO) closure after a cryptogenic cerebral ischemic event is a routinely procedure. The most used device is Amplatzer™ PFO Occluder 25 mm, but PFOs with complex anatomy require larger device for closure. We compared Amplatzer™ Septal Occluder (ASO) device versus Amplatzer™ PFO Occluder 3...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.10.053
更新日期:2019-03-15 00:00:00
abstract::Tachycardias mediated by atrioventricular accessory pathways, which are refractory to antiarrhythmic drug therapy have been treated both by surgery and by catheter ablation with high energy direct current shock. These procedures have variable success rates and substantial associated morbidity and mortality. Radiofrequ...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
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更新日期:1993-12-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2005.11.085
更新日期:2007-01-18 00:00:00
abstract:BACKGROUND/OBJECTIVES:Inflammation contributes to the pathogenesis of disease associated with the left ventricle (LV); yet, our understanding of the effect of inflammation on the right ventricle (RV) is quite limited. METHODS AND RESULTS:The relationships of C-reactive protein (CRP), interleukin-6 (IL-6) and fibrinoge...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2013.06.028
更新日期:2013-10-09 00:00:00