Abstract:
:The ratio between maximal and minimal R-R intervals measured during the Valsalva maneuver is an adequate means of studying the functional state of the cardiac parasympathetic nervous system. We studied the changes in heart rate evoked during the Valsalva maneuver in 49 asymptomatic Chagasic patients with different degrees of myocardial involvement. The Chagasic patients were divided in three groups. Twelve patients had no evidence of heart disease except for an abnormal myocardial biopsy. Sixteen patients had a normal electrocardiogram but revealed evidence of localized myocardial damage as shown by left ventricular cineangiography. Twenty-one patients had abnormal electrocardiograms and revealed multiple areas of abnormal left ventricular wall motion. The Valsalva ratio (mean +/- standard error) was 1.62 +/- 0.12 for controls, 1.52 +/- 0.10 for those with an abnormal biopsy, 1.48 +/- 0.06 for those with localized myocardial damage, and 1.31 +/- 0.04 for those with an abnormal electrocardiogram. There were no statistically significant differences between the control group (normal sero-negative subjects) and those patients with normal electrocardiograms. Results in those with an abnormal electrocardiogram, however, were statistically different (P less than 0.05) from the other groups. These results are in discordance with the commonly accepted hypothesis that cardiac parasympathetic denervation causes a dilated myocardiopathy in patients with chronic Chagasic myocarditis.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Fuenmayor AJ,Rodriguez L,Torres A,Donís J,Navas M,Fuenmayor AM,Dávila Ddoi
10.1016/0167-5273(88)90053-8subject
Has Abstractpub_date
1988-03-01 00:00:00pages
351-6issue
3eissn
0167-5273issn
1874-1754pii
0167-5273(88)90053-8journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Many patients fail to receive β-blockers before cardiac resynchronization therapy defibrillator (CRT-D) implantation, or receive them at a suboptimal dose, and require optimization after implantation. We assessed the effectiveness of a structured program for β-blocker titration in CRT-D patients followed up ...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2017-06-01 00:00:00
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journal_title:International journal of cardiology
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pub_type: 评论,信件
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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pub_type: 信件,评审
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journal_title:International journal of cardiology
pub_type: 共识发展会议,杂志文章
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journal_title:International journal of cardiology
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pub_type: 临床试验,杂志文章
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更新日期:2000-07-31 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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更新日期:2018-11-15 00:00:00
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pub_type: 杂志文章
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更新日期:2011-10-20 00:00:00
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pub_type: 信件
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更新日期:2009-05-01 00:00:00
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pub_type: 杂志文章
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