Abstract:
BACKGROUND:Adult females have significantly more leptin than males. We investigated the effect of fetal sex on levels of leptin and other pregnancy hormones (progesterone, estradiol, FSH, LH and beta hCG) in pregnant females during different stages of pregnancy. PATIENTS AND METHODS:Serum leptin levels in pregnant females followed at King Khaled University Hospital, Riyadh, Saudi Arabia in the year 2001 were estimated at the first, second, and third trimester of pregnancy as well as after delivery. Progesterone, estradiol, FSH, LH and beta hCG levels were also measured. RESULTS:Leptin levels were significantly higher during all three trimesters in the pregnant females carrying female fetuses compared with those with male fetuses, while other hormones did not differ between the two groups. After delivery, the leptin levels decreased in both groups, and were still higher in the females who delivered baby girls, but the results were not statistically significant. CONCLUSION:These finding suggests that leptin might play a role in sex regulation during embryonic development.
journal_name
Ann Saudi Medjournal_title
Annals of Saudi medicineauthors
Al Atawi F,Warsy A,Babay Z,Addar Mdoi
10.5144/0256-4947.2005.124subject
Has Abstractpub_date
2005-03-01 00:00:00pages
124-8issue
2eissn
0256-4947issn
0975-4466journal_volume
25pub_type
杂志文章abstract:BACKGROUND:Nasal polyposis is a common problem in the eastern province of Saudi Arabia. Since allergic fungal sinusitis (AFS) can present with unilateral or bilateral nasal polyps, it is important to be aware of the prevalence of AFS in patients with nasal polyps. PATIENTS AND METHODS:The medical records of 91 patient...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2009.212
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:We tested the clinical utility of the platelet count, the aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio, and the AST to platelet ratio index (APRI) score in predicting the presence or absence of advanced fibrosis and cirrhosis in patients with chronic hepatitis C in Saudi Arabia. METHO...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2007.89
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Familial hypercholesterolemia (FH) is an autosomal dominant condition characterized by abnormal levels of low-density lipoprotein (LDL) in the blood. FH is a risk factor for atherosclerosis and cardiovascular disease. The relationship between the paraoxonase 1 (PON1) gene, atherosclerosis and coronary artery...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2017.425
更新日期:2017-11-01 00:00:00
abstract::A study of accessibility, availability, and acceptability of immunization was carried out by interviewing 1422 parents selected randomly from the catchment areas of 15 health care centers in Riyadh. The parents were included if they had children who were under two years or who had not completed the essential immunizat...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1992.339
更新日期:1992-07-01 00:00:00
abstract::Cerebral palsy (CP) is a common pediatric disorder occurring in about 2 to 2.5 per 1000 live births. It is a chronic motor disorder resulting from a non-progressive (static) insult to the developing brain. CP is the clinical presentation of a wide variety of cerebral cortical or sub-cortical insults occurring during t...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.5144/0256-4947.2006.123
更新日期:2006-03-01 00:00:00
abstract::Although the medical literature contains adequate accounts of the pathophysiology of various benign prostatic disorders, it is often necessary to revisit these lesions, to reexamine the relationships between known benign lesions and more sinister, malignant disorders, in the light of new advances in our understanding ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1998.22
更新日期:1998-01-01 00:00:00
abstract::Cigarette smoking is universally acknowledged to be a health hazard. We are of the opinion that primary health care (PHC) physicians can potentially play a key role in the promotion of non-smoking campaigns. The aim of this study was to determine the role of male PHC physicians in the promotion of a non-smoking campai...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1997.515
更新日期:1997-09-01 00:00:00
abstract::Two cases of Strongyloides stercoralis hyperinfection are described. Both patients were expatriates from the Indian subcontinent, and reported the use of corticosteroids. The first patient presented with severe pulmonary disease that necessitated respiratory support, followed by acute abdomen and intestinal obstructio...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.4103/0256-4947.55172
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Autosomal recessive primary microcephaly (MCPH) is a clinically and genetically heterogeneous disorder. Patients with MCPH exhibit reduced occipito-frontal head circumference and non-progressive intellectual disability. To date, 17 genes have been known as an underlying cause of MCPH in humans. ASPM (abnorma...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2016.391
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Multiple surveys of medical residents have shown a high incidence of harassment and discrimination in academic health centers. Harassment has a negative effects on residents' health and on their ability to function. No previous study has documented the prevalence of harassment and discriminati...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,多中心研究
doi:10.5144/0256-4947.2013.134
更新日期:2013-03-01 00:00:00
abstract::This preliminary study done by abstracting relevant data from different testing material and using multiple rating scales, describes the sociodemographic variables, psychopathological correlates, and features of trihexyphenidyl (artane) abuse in a sample of 14 Saudi psychiatric patients and, as a result of this resear...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1992.391
更新日期:1992-07-01 00:00:00
abstract::We have presented an interesting case of an unexpected orbital tumor in a 5-month-old female healthy baby who presented initially with a 1-week history of acute left proptosis, swollen eyelid, conjunctival chemosis and exposure keratopathy. She was treated with intravenous antibiotics without any improvement and was r...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2013.623
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Fetal growth is the result of interactions between various factors and can be estimated by ultrasonic measurements. Fetal femur length is a scale for estimating the fetal weight in individual races because fetal growth patterns differ among different races. SUBJECTS AND METHODS:This was a prospective study ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2007.179
更新日期:2007-05-01 00:00:00
abstract::Schistosomiasis (also known as bilharzia, bilharziasis, bilharziosis or snail fever) is a human disease syndrome caused by infection from one of several species of parasitic trematodes of the genus Schistosoma. The three main species infecting humans are S haematobium, S japonicum, and S mansoni. S japonicum is most c...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.4103/0256-4947.51800
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:While the role of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST) in the diagnosis and management of choledocholithiasis is well established, this study evaluates the usefulness of ERCP and EST in patients with symptomatic cholecystolithiasis and suspected choledocho...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1998.117
更新日期:1998-03-01 00:00:00
abstract::Acroangiodermatitis (AAD) (synonym, pseudo-Kaposi sarcoma) is a term that encompasses 2 different conditions: (1) AAD of Mali, which refers to skin lesions that mainly develop bilaterally on the lower extremities of patients with chronic venous insufficiency and is an extreme form of stasis dermatitis and (2) Stewart-...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2014.179
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Streptococcus pneumoniae is a major cause of mortality and morbidity in both developing and industrialized countries, especially among young children and in both immunocompromised and immunocompetent individuals. It is implicated in both invasive (e.g. meningitis and septicemia) as well as noni...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.4103/0256-4947.83214
更新日期:2011-07-01 00:00:00
abstract::Neonatal diabetes mellitus is considered a rare disease that is diagnosed in the first six months of life, and can be either transient or permanent. Recent advances in molecular genetics have shown that activating mutations in KCNJ11 (the gene that encodes for the Kir6.2 subunit of the K ATP potassium channel of the p...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.4103/0256-4947.60526
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:The differentiation of extramedullary myelogenous leukemia/granulocytic sarcoma (GS) from malignant lymphoma can sometimes be difficult. In the current study, we explored the value of CD34, myeloperoxidase and nonspecific esterase (Leder) stains in differentiating GS from lymphomas. MATERIALS AND METHODS:Fi...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2001.287
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Central venous cannulation is a necessary invasive procedure for fluid management, haemodynamic monitoring and vasoactive drug therapy. The right internal jugular vein (RIJV) is the preferred site. Enlargement of the jugular vein area facilitates catheterization and reduces complication rates. Common methods...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2017.308
更新日期:2017-07-01 00:00:00
abstract::Myocardial perfusion single photon emission-computed tomography (MPS) has been one of the most important and common non-invasive diagnostic cardiac test. Gated MPS provides simultaneous assessment of myocardial perfusion and function with only one study. With appropriate attention to the MPS techniques, appropriate cl...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.4103/0256-4947.87101
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:The laparoscopic approach for adrenalectomy is now widely accepted and preferred over the conventional open approach. We describe our experience of adreanalectomy and compare the results of open and laparoscopic approach. PATIENTS AND METHODS:From March 1999 to March 2002, we performed 23 adrenalectomies. A...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2003.36
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Infantile colic is a common problem among young infants. Cow's milk allergy has been suggested as one of the causes. We aimed to investigate the value of the cow's milk skin test for the diagnosis of cow's milk allergy in exclusively breast-fed infants with infantile colic. METHODS:Exclusivel...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,随机对照试验
doi:10.4103/0256-4947.72269
更新日期:2010-11-01 00:00:00
abstract::Obesity, as a core component of the metabolic syndrome, is among the top ten global health risks classified by the World Health Organization (WHO) as being strongly associated with the development and progression of chronic renal disease--a widely prevalent but often silent condition. Obesity carries elevated risks of...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.5144/0256-4947.2006.288
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To compare the complications and outcome after ileal pouch-anal anastomosis (IPAA) for mucosal ulcerative colitis (MUC) and familial adenomatous polyposis (FAP). DESIGN AND SETTINGS:This is a retrospective study. The study was conducted at a single tertiary referral center. METHODS:All patie...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2013.268
更新日期:2013-05-01 00:00:00
abstract::The Cosman-Roberts-Wells (CRW-3) scanner independent stereotactic system is a recent arc-radius design developed from the Brown-Roberts-Wells system. The results of 74 supratentorial non-basal tumor suspect cases treated with this second generation computed tomography (CT) guided stereotactic apparatus are presented. ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1994.507
更新日期:1994-11-01 00:00:00
abstract::The main purpose of this report is to describe nine cases of xeroderma pigmentosum with primary spontaneous corneal scarring in the absence of history of corneal ulcers or infectious keratitis. The authors studied nine patients with xeroderma pigmentosum. Each patient underwent complete ophthalmologic and dermatologic...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1996.296
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Dentists suffer a high prevalence of musculoskeletal disorders (MSDs) but studies are quite limited. The present study was carried out to investigate the prevalence of MSDs among dentists in the Ha'il Region, Saudi Arabia. DESIGN AND SETTINGS:A cross-sectional, questionnaire study was conduct...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2015.456
更新日期:2015-11-01 00:00:00
abstract::A review of 100 referral letters and reports randomly selected from two health centers in Riyadh identified that the main reason for referral was general therapeutic advice (43.2%), general diagnostic evaluation (24.8%), and routine specialist examination (11.7%). Of the total referrals, 82.1% were seen within a week ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1991.658
更新日期:1991-11-01 00:00:00
abstract::Although cataract surgery is increasingly being performed under local anesthesia in many centers, general anesthesia is preferred for cataract surgery at the King Fahd Hospital of the University (KFHU), Al-Khobar. Ninety two patients who had cataract extraction under general anesthesia at KFHU between October 1988 and...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1992.13
更新日期:1992-01-01 00:00:00