The burden of pneumococcal disease in children less than 5 years of age in Abu Dhabi, United Arab Emirates.

Abstract:

BACKGROUND AND OBJECTIVE:Streptococcus pneumoniae is a major cause of mortality and morbidity in both developing and industrialized countries, especially among young children and in both immunocompromised and immunocompetent individuals. It is implicated in both invasive (e.g. meningitis and septicemia) as well as noninvasive disease (community-acquired pneumonia and otitis media). The objective of the current study was to describe the overall epidemiology of both invasive and noninvasive pneumococcal disease in Abu Dhabi over a 5-year period. DESIGN AND SETTING:Retrospective review of all pediatric (≤ 5 year old) pneumococcal disease admissions to Shaikh Khalifa Medical City (SKMC) and Mafraq Hospital in Abu Dhabi from 1 January 2001 till 31 December 2005.th METHODS:We retrieved computerized data from the health information management systems (International Classification of Diseases, 9th Revision (ICD9) diagnosis codes) as well as manual surveillance in the laboratory record of pneumococcal isolates. RESULTS:The incidence of invasive pneumococcal disease was 13.6/100, 000 per year (95% CI, 6.5-24.9) and the incidence of noninvasive pneumococcal disease was 172.5/100,000 per year (95% CI, 143.8-205.2). The total incidence rate was 186.0/100, 000 per year (95% CI, 156.2-219.9). CONCLUSION:This epidemiological survey indicates that the incidence rates in the United Arab Emirate are higher than in Western countries where conjugate pneumococcal vaccine has been introduced. This study is important as it documents the incidence of pneumococcal disease in the era before introduction of the conjugate pneumococcal vaccine and allows for future research to document the impact of a new vaccine considering the geographic variation of pneumococcal serotypes.

journal_name

Ann Saudi Med

journal_title

Annals of Saudi medicine

authors

Howidi M,Muhsin H,Rajah J

doi

10.4103/0256-4947.83214

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

356-9

issue

4

eissn

0256-4947

issn

0975-4466

pii

AnnSaudiMed_2011_31_4_356_83214

journal_volume

31

pub_type

杂志文章
  • Validation of three noninvasive laboratory variables to predict significant fibrosis and cirrhosis in patients with chronic hepatitis C in Saudi Arabia.

    abstract:BACKGROUND:We tested the clinical utility of the platelet count, the aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio, and the AST to platelet ratio index (APRI) score in predicting the presence or absence of advanced fibrosis and cirrhosis in patients with chronic hepatitis C in Saudi Arabia. METHO...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2007.89

    authors: Abdo AA,Al Swat K,Azzam N,Ahmed S,Al Faleh F

    更新日期:2007-03-01 00:00:00

  • Q192R polymorphism in the PON1 gene and familial hypercholesterolemia in a Saudi population.

    abstract:BACKGROUND:Familial hypercholesterolemia (FH) is an autosomal dominant condition characterized by abnormal levels of low-density lipoprotein (LDL) in the blood. FH is a risk factor for atherosclerosis and cardiovascular disease. The relationship between the paraoxonase 1 (PON1) gene, atherosclerosis and coronary artery...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2017.425

    authors: Alharbi KK,Alnbaheen MS,Alharbi FK,Hasanato RM,Khan IA

    更新日期:2017-11-01 00:00:00

  • Subchorionic hematoma in threatened abortion: Sonographic evaluation and significance.

    abstract::In a study of 92 women with subchorionic hematoma evaluated with sonographic scan in King Khalid University Hospital, it was found that the mean ages and live births of patients who carried their pregnancies to viability were higher when compared with the patients who aborted. There was a statistically significant ass...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1996.650

    authors: Al Nuaim L,Chowdhury N,Adelusi B

    更新日期:1996-11-01 00:00:00

  • Outcome after ileal pouch-anal anastomosis for familial adenomatous polyposis compared to mucosal ulcerative colitis in a Middle Eastern population.

    abstract:BACKGROUND AND OBJECTIVES:To compare the complications and outcome after ileal pouch-anal anastomosis (IPAA) for mucosal ulcerative colitis (MUC) and familial adenomatous polyposis (FAP). DESIGN AND SETTINGS:This is a retrospective study. The study was conducted at a single tertiary referral center. METHODS:All patie...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2013.268

    authors: Al-Sanea N,Alfaifi J,Homoud SA,Abduljabbar A,Hibbert D,Ashari L

    更新日期:2013-05-01 00:00:00

  • The monitoring of potential long-term comlications in treated adult cancer patients.

    abstract::A wide variety of long-term complications may be noted following conventional cancer treatment. These include overwhelming postsplenectomy sepsis syndrome, central and peripheral nervous system toxicity, cardiovascular complications, chronic liver damage, and secondary malignancy. Follow-up monitoring usually incorpor...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1997.622

    authors: Brigden ML

    更新日期:1997-11-01 00:00:00

  • Predicting glucose intolerance with normal fasting plasma glucose by the components of the metabolic syndrome.

    abstract:BACKGROUND:Surprisingly, it is estimated that about half of type 2 diabetics remain undetected. The possible causes may be partly attributable to people with normal fasting plasma glucose (FPG) but abnormal postprandial hyperglycemia. We attempted to develop an effective predictive model by using the metabolic syndrome...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2007.339

    authors: Pei D,Lin JD,Wu DA,Hsieh CH,Hung YJ,Kuo SW,Kuo KL,Wu CZ,Li JC

    更新日期:2007-09-01 00:00:00

  • Benign disorders of the prostate: A histopathological study.

    abstract::Although the medical literature contains adequate accounts of the pathophysiology of various benign prostatic disorders, it is often necessary to revisit these lesions, to reexamine the relationships between known benign lesions and more sinister, malignant disorders, in the light of new advances in our understanding ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1998.22

    authors: Anim JT,Ebrahim BH,Sathar SA

    更新日期:1998-01-01 00:00:00

  • Pulse cyclophosphamide therapy for steroid-resistant focal segmental glomerulosclerosis in children.

    abstract:BACKGROUND:In children, steroid-resistant nephritic syndrome due to focal segmental glomerulosclerosis (FSGS) is frequently a progressive condition resulting in end-stage renal disease (ESRD). We report the response of 15 patients with steroid resistant FSGS to treatment with intravenous pulse cyclophosphamide (IVCP) a...

    journal_title:Annals of Saudi medicine

    pub_type: 临床试验,杂志文章

    doi:10.5144/0256-4947.2004.27

    authors: Al Salloum AA

    更新日期:2004-01-01 00:00:00

  • Predictive value of the cow's milk skin prick test in infantile colic.

    abstract:BACKGROUND AND OBJECTIVES:Infantile colic is a common problem among young infants. Cow's milk allergy has been suggested as one of the causes. We aimed to investigate the value of the cow's milk skin test for the diagnosis of cow's milk allergy in exclusively breast-fed infants with infantile colic. METHODS:Exclusivel...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.4103/0256-4947.72269

    authors: Moravej H,Imanieh MH,Kashef S,Handjani F,Eghterdari F

    更新日期:2010-11-01 00:00:00

  • Appendiceal ascariasis in children.

    abstract:BACKGROUND:The propensity of Ascaris lumbricoides to wander leads to varied surgical complications in the abdomen. Wandering A lumbricoides may sometimes reach the vermiform appendix and its presence there may remain silent or incite pathology. Our aim was to study ascariadial appendicitis. METHODS:Over a period of 3 ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.4103/0256-4947.59380

    authors: Wani I,Maqbool M,Amin A,Shah F,Keema A,Singh J,Kitagawa M,Nazir M

    更新日期:2010-01-01 00:00:00

  • Dermatophytes and other fungi associated with skin mycoses in Tripoli, Libya.

    abstract:BACKGROUND:Our objective in this study was to obtain information on the prevalence of fungi responsible for superficial mycoses in the region of Tripoli, Libya. PATIENTS AND METHODS:Skin scrapings collected from 2224 patients attending the Dermatology Clinic at Tripoli Medical Center with suspected clinical symptoms o...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2001.193

    authors: Ellabib MS,Khalifa ZM

    更新日期:2001-05-01 00:00:00

  • Chronic spontaneous cervicothoracic epidural hematoma in an 8-month-old infant.

    abstract::Spontaneous spinal epidural hematoma is an uncommon cause of cord compression in children, especially in infants. An 8-month-old infant was admitted to our hospital for a 40-day history of paraparesis in the lower extremities. This rapidly progressed to paraparesis with an inability to move the lower extremities. MRI ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.4103/0256-4947.75586

    authors: Min S,Duan Y,Jin A,Zhang L

    更新日期:2011-05-01 00:00:00

  • Coronary artery calcium score in high-risk asymptomatic women in Saudi Arabia.

    abstract:BACKGROUND AND OBJECTIVE:Coronary artery calcification (CAC) is indicated by calcium deposits in the coronary artery wall. Calcification is a component of atherosclerosis and coronary artery disease. Currently, there are no data on calcification in Saudi women at high risk of coronary artery disease. The aim of this st...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2015.298

    authors: Fathala A,Alreshoodi S,Rujaib MA,Shoukri M,Sergani HA,Buriki JA,Sugair AA

    更新日期:2015-07-01 00:00:00

  • Steroid therapy for post-tonsillectomy symptoms in adults: a randomized, placebo-controlled study.

    abstract:BACKGROUND:Post-operative morbidity following tonsillectomy remains an important clinical problem despite advances in anesthetic and surgical techniques. This study investigated the effect of a one-day course of intravenous dexamethasone on recovery from tonsillectomy. PATIENTS AND METHODS:In a double-blind, randomize...

    journal_title:Annals of Saudi medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.5144/0256-4947.2004.365

    authors: Al-Shehri AM

    更新日期:2004-09-01 00:00:00

  • Genotyping of rifampin-resistant Mycobacterium tuberculosis isolates from western Turkey.

    abstract:BACKGROUND:Although the rate of multiple drug resistance is high, there is no published data on the transmission rate of drug-resistant strains of Mycobacterium tuberculosis in the Aegean region of western Turkey that are based on molecular methods. METHODS:IS6110 and pTBN12 restriction fragment length polymorphism (R...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2004.102

    authors: Cavusoglu C,Durmaz R,Bilgic A,Gunal S

    更新日期:2004-03-01 00:00:00

  • Q fever: a neglected zoonosis in Saudi Arabia.

    abstract:BACKGROUND AND OBJECTIVES:Infection due to Coxiella burnetii (C burnetii), the causative agent of Q fever is rarely sought for in clinical practice. This study was performed to detect C burnetii infection in patients with pyrexia of undetermined cause (PUC). DESIGN AND SETTINGS:This is a prospective study conducted at...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2013.464

    authors: Almogren A,Shakoor Z,Hasanato R,Adam MH

    更新日期:2013-09-01 00:00:00

  • Comparison of the Trendelenburg position versus upper-limb tourniquet on internal jugular vein diameter.

    abstract:BACKGROUND:Central venous cannulation is a necessary invasive procedure for fluid management, haemodynamic monitoring and vasoactive drug therapy. The right internal jugular vein (RIJV) is the preferred site. Enlargement of the jugular vein area facilitates catheterization and reduces complication rates. Common methods...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2017.308

    authors: Karaaslan P,Gokay BV,Karakaya MA,Darcin K,Karakaya AD,Ormeci T,Kose EA

    更新日期:2017-07-01 00:00:00

  • Disseminated peritoneal Schistosoma japonicum: a case report and review of the pathological manifestations of the helminth.

    abstract::Schistosomiasis (also known as bilharzia, bilharziasis, bilharziosis or snail fever) is a human disease syndrome caused by infection from one of several species of parasitic trematodes of the genus Schistosoma. The three main species infecting humans are S haematobium, S japonicum, and S mansoni. S japonicum is most c...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章,评审

    doi:10.4103/0256-4947.51800

    authors: Al-Waheeb S,Al-Murshed M,Dashti F,Hira PR,Al-Sarraf L

    更新日期:2009-03-01 00:00:00

  • Bilharzial and nonbilharzial bladder cancer in Asir: A comparative clinicopathological study.

    abstract::A total of 48 bladder cancer patients out of 96 consecutive genitourinary cancer cases were divided into bilharzial and nonbilharzial groups on a histological basis in order to investigate the impact of bilharziasis on tumor behavior. Despite being a bilharzial endemic area, only 10/48 (21%) of our patients had bilhar...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1993.151

    authors: Shetty SD,Ibrahim AI,Patil KP,Morad NA,Anandan N,Khurana P

    更新日期:1993-03-01 00:00:00

  • Laparoscopic vs. open adrenalectomy: experience at King Faisal Specialist Hospital and Research Centre, Riyadh.

    abstract:BACKGROUND:The laparoscopic approach for adrenalectomy is now widely accepted and preferred over the conventional open approach. We describe our experience of adreanalectomy and compare the results of open and laparoscopic approach. PATIENTS AND METHODS:From March 1999 to March 2002, we performed 23 adrenalectomies. A...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2003.36

    authors: Yousef HB,Al Zahrani A,Ahmed M,Al Arifi A,Mahfouz A,Hussain R,Al-Sobhi S

    更新日期:2003-01-01 00:00:00

  • Health-related quality of life in type 2 diabetic patients.

    abstract:BACKGROUND AND OBJECTIVES:Health-related quality of life (HRQOL) is an important health outcome, representing one of the most important goals of all health interventions. The objectives of this study were to determine HRQOL and the factors affecting it in type 2 diabetic patients. PATIENTS AND METHODS:This cross-secti...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2008.352

    authors: Al-Shehri AH,Taha AZ,Bahnassy AA,Salah M

    更新日期:2008-09-01 00:00:00

  • Hypnosis for sedation in transesophageal echocardiography: a comparison with midazolam.

    abstract:BACKGROUND:Transesophageal echocardiography (TEE), being a displeasing intervention, usually entails sedation. We aimed to compare the effects of hypnosis and midazolam for sedation in TEE. DESIGN AND SETTINGS:A prospective single-blinded study conducted on patients scheduled for TEE between April 2011 and July 2011 a...

    journal_title:Annals of Saudi medicine

    pub_type: 临床试验,杂志文章

    doi:10.5144/0256-4947.2015.58

    authors: Eren G,Dogan Y,Demir G,Tulubas E,Hergunsel O,Tekdos Y,Dogan M,Bilgi D,Abut Y

    更新日期:2015-01-01 00:00:00

  • Pseudo-Kaposi sarcoma worsening after leg vein harvest for coronary artery bypass grafting.

    abstract::Acroangiodermatitis (AAD) (synonym, pseudo-Kaposi sarcoma) is a term that encompasses 2 different conditions: (1) AAD of Mali, which refers to skin lesions that mainly develop bilaterally on the lower extremities of patients with chronic venous insufficiency and is an extreme form of stasis dermatitis and (2) Stewart-...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2014.179

    authors: Alshihry H,Chisti MA,Hamadah I

    更新日期:2014-03-01 00:00:00

  • Five year experience in prenatal ultrasound diagnosis of esophageal atresia in Saudi Arabia.

    abstract:BACKGROUND:Esophageal atresia (EA), with or without tracheoesophageal fistula (TOF) is one of the most correctable fetal anomalies if diagnosed antenatally by serial ultrasound. We retrospectively evaluated antenatal diagnoses by ultrasound of EA with or without TOF at our institution in Saudi Arabia. PATIENTS AND MET...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2003.132

    authors: Khorshid EA,Dokhan AL,Turkistani AF,Shadi SM,Hassab MH

    更新日期:2003-05-01 00:00:00

  • Familial clustering of type II diabetes mellitus (DM) diagnosed under the age of 40 years in Yemen: Is it early-onset type II DM or maturity-onset diabetes of the young?

    abstract:BACKGROUND:Clinical presentation of type II diabetes mellitus (DM) has frequently been observed at an early age in developing countries, probably as a result of genetic, epidemiological and demographic factors. This study aimed to investigate the pattern of familial clustering of type II DM in patients who developed cl...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1999.308

    authors: Gunaid AA

    更新日期:1999-07-01 00:00:00

  • Survival and metastasis in muscle-invasive bladder cancer patients who present with indeterminate pulmonary nodules before treatment.

    abstract:BACKGROUND:Indeterminate pulmonary nodules (IPNs) are common during initial evaluation of bladder cancer patients. Their significance is still unknown. OBJECTIVE:Determine the significance of indeterminate pulmonary nodules, including their size and number, in muscle-invasive bladder cancer patients before definitive ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2019.42

    authors: Al-Daghmin A,Alhamss S,Al-Najjar H,Al-Saidi I,Al-Qasem K,Abukhiran I,Hamad A,Alhusban M

    更新日期:2019-01-01 00:00:00

  • Placental steroid sulphatase deficiency: an approach to antenatal care and delivery.

    abstract::Placental steroid sulphatase deficiency (SSD) is an X-linked inborn error of metabolism. Congenital X-linked ichthyosis (XLI) is a genetic disorder of keratinisation caused by steroid sulphatase (STS) deficiency, which results in a scaling skin condition in male infants shortly after birth. It may be associated with f...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2018.445

    authors: Dreyer FE,Abdulrahman GO,Waring G,Hinshaw K

    更新日期:2018-11-01 00:00:00

  • Aberrant internal carotid artery in the middle ear.

    abstract::An aberrant internal carotid artery (ICA) in the middle ear space can present in 1% of the population. The clinical diagnosis can be difficult as most patients with this anomaly are either asymptomatic or have nonspecific clinical symptoms and signs. Moreover the diagnosis can easily be missed and only discov.ered whe...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.2013.194

    authors: Alharethy S

    更新日期:2013-03-01 00:00:00

  • The morphological spectrum of tumors of adipose tissue: A pathological analysis of 685 tumors.

    abstract::Over a seven-year period, 1093 cases of tumors of soft-tissue origin were recorded by the Pathology Department of King Fahd Hospital of the University, Al-Khobar. Of these, detailed histopathological analysis was performed on 685 tumors of adipose-tissue origin removed from 640 patients. Of the 45 multiple tumors, 31 ...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1991.28

    authors: Satti MB

    更新日期:1991-01-01 00:00:00

  • Upper gastrointestinal hemorrhage in Jordan: An analysis of causes, characteristics and outcome.

    abstract::Two hundred twenty-four patients presenting consecutively with massive upper gastrointestinal hemorrhage were endoscoped within 24 hours to determine the site of bleeding. Outcome was evaluated in relation with presenting variables. Duodenal ulcer was found to be the most common source of bleeding. Endoscopy demonstra...

    journal_title:Annals of Saudi medicine

    pub_type: 杂志文章

    doi:10.5144/0256-4947.1991.539

    authors: Toukan AU

    更新日期:1991-09-01 00:00:00