Prevalence of allergic fungal sinusitis among patients with nasal polyps.

Abstract:

BACKGROUND:Nasal polyposis is a common problem in the eastern province of Saudi Arabia. Since allergic fungal sinusitis (AFS) can present with unilateral or bilateral nasal polyps, it is important to be aware of the prevalence of AFS in patients with nasal polyps. PATIENTS AND METHODS:The medical records of 91 patients with nasal polyps admitted for functional endoscopic sinus surgery were reviewed. The diagnosis of AFS was considered if histopathology showed the presence of eosinophillic mucin-containing hyphae. The following data were collected: presence of associated asthma, IgE levels, grading of CT scan findings, and operative details. RESULTS:Histopathological diagnosis was positive for AFS in 11 of 91 patients 12.1%. There was a highly significant statistical difference in IgE levels between patients suffering AFS and chronic hyperplastic rhinosinusitis with nasal polyps (P<.0001). The overall incidence of recurrence of polypi was 50.5% (45 of 89 patients who had follow up for a minimum of one year) and the rate of recurrence in patients with AFS was 54.5% (6 of 11 patients with AFS). There was a significant direct relationship between the CT grading of nasal polyps and recurrence, with a recurrence rate of 60.7% (34 of 56) in patients with grade III nasal polyps. CONCLUSION:This study showed that the prevalence of AFS among patients with nasal polyps is 12.1%, and suggests that CT grading of nasal polyps can be used as a prognostic factor for disease recurrence.

journal_name

Ann Saudi Med

journal_title

Annals of Saudi medicine

authors

Telmesani LM

doi

10.5144/0256-4947.2009.212

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

212-4

issue

3

eissn

0256-4947

issn

0975-4466

pii

08-584

journal_volume

29

pub_type

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