Abstract:
PURPOSE:To describe the visual phenotype of multiple sclerosis (MS) in the Afro-Caribbean population living in Martinique (French West Indies) and to specify the influence of the migration to metropolitan France on ocular impairment. DESIGN:Prospective consecutive observational case series. METHODS:A complete ophthalmologic examination was performed. PARTICIPANTS:A total of 112 patients of Afro-Caribbean origin with MS satisfying McDonald's diagnostic criteria, divided into 53 cases (47.3%), the non-migrant patients (group NM), who had never left the Caribbean basin, and 59 cases (52.7%), the migrant patients (group M), who had lived in metropolitan France for at least 1 year before age 15. RESULTS:MS first manifested as an impairment of the optic nerve in 41 cases (36.6%): 25 cases (47.1%) in group NM and 16 cases (27.1%) in group M. Visual function was recovered in 13/25 cases (52%) in group NM compared to 13/16 cases (81%) in group M. Two-thirds of patients presented with a clinical ocular impairment, which was bilateral in 58.5% of cases in group NM. Fourteen cases (12.5%) met the criteria of neuromyelitis optica, nine cases (17%) in group NM and five cases (8.5%) in group M. In group NM, when the initial visual attack did not regress, the visual Expanded Disability Status Scale (EDSS) score was 5+/-1.5 ; 75% of patients had monocular blindness and 50% binocular. CONCLUSIONS:In the non-migrants (group NM), MS manifested more frequently with an optical neuropathy, the ocular impairment was more severe, and corresponded to neuromyelitis optica in 17% of the cases; a visual presentation and the absence of complete recovery from the first attack represented a factor of poor prognosis. This series is the largest description of the visual phenotype of MS in patients of African origin. The results confirm the preferential impairment of the optic nerve in the black population in the course of the disease. The migration towards an area of high prevalence of MS influences the visual phenotype in terms of a lower incidence and less severe prognosis of ocular impairment.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Merle H,Smadja D,Merle S,Olindo S,Signate A,Donnio A,Richer R,Bonnan M,Cabre Pdoi
10.1177/112067210501500313subject
Has Abstractpub_date
2005-05-01 00:00:00pages
392-9issue
3eissn
1120-6721issn
1724-6016journal_volume
15pub_type
杂志文章abstract:PURPOSE:To report the long-term surgical outcome of vitrectomy for cystoid macular edema due to nonischemic central retinal vein occlusion (CRVO). METHODS:A retrospective chart review of 25 consecutive eyes (25 patients) with cystoid macular edema due to nonischemic CRVO treated with vitrectomy was performed. All pati...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600609
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:To compare the results of viscocanalostomy with and without mitomycin-C (MMC). METHODS:Retrospective results of 15 standard viscocanalostomy (VCO) operations (Group 1) were compared with the prospective results of 15 VCO operations performed with intraoperative adjunctive MMC (Group 2). MMC (0.2 mg/mL) was app...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1177/112067210501500204
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:To report on phototherapeutic keratectomy (PTK) in myopic patients who developed spontaneous recurrent corneal erosions (RCE) following IntraLASIK. METHODS:Recurrent corneal erosions developed spontaneously 3-6 months following IntraLASIK in 4 eyes of 4 myopic patients. Diffuse lamellar keratitis (DLK) subsequ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000097
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To present a new indicator that measures the sulci of the lacrimal lake of the eye according to the degrees of ocular abduction at which they vanish. This new approach will help determine the severity and progression of mucosal retraction in ocular surface diseases. METHODS:A total of 181 eyes of 94 healthy pe...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100303
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:To describe a patient who developed diplopia, lagophthalmos and exposure keratopathy due to a large subconjunctival emphysema. METHODS:A 24-year-old man sustained an injury in his left eye from a compressed air hose. The patient complained of pain and diplopia. He underwent slit-lamp examination, funduscopy an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300113
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800104
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of astigmatism axis on uncorrected distance visual acuity (UDVA) in emmetropic eyes that underwent laser refractive surgery. METHODS:This retrospective study included patients who underwent laser in situ keratomileusis or photorefractive keratectomy between January 2000 and December 2015...
journal_title:European journal of ophthalmology
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更新日期:2017-05-11 00:00:00
abstract:PURPOSE:To investigate a new method for assessing the thickness of the retinal nerve fiber layer thickness (NFLT) for glaucoma diagnosis, using scanning laser polarimetry. MATERIAL AND METHODS:Thirty eyes of thirty patients with ocular hypertension or glaucoma were examined using a scanning laser polarimeter. NFL T wa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067219900900204
更新日期:1999-04-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2015-09-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2020-08-27 00:00:00
abstract:PURPOSE:Ocular toxoplasmosis is associated with vitreoretinal complications that can potentially cause severe visual loss. The aim of this study is to report the preoperative, intraoperative, and postoperative outcomes of vitreous surgery in eyes with vitreoretinal complications secondary to ocular toxoplasmosis. METH...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of fixed-combination brimonidine tartrate 0.2%/timolol 0.5% ophthalmic solution dosed BID and demonstrate non-inferiority to concomitant use of brimonidine tartrate 0.2% BID and timolol 0.5% BID in glaucoma and ocular hypertension patients with intraocular pressure (IOP) unco...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4076
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To investigate localized retinal dysfunction in hypertensive patients using multifocal electroretinogram (mfERG) and to assess its sensitivity as an early predictor for the development of retinopathy in hypertensive patients. METHODS:Ninety-eight eyes were included in this case-control study. Twenty-eight eyes...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120934750
更新日期:2020-06-12 00:00:00
abstract:PURPOSE:To determine the outcome, including the intraoperative and postoperative complications, of phacoemulsification with intraocular lens (IOL) implantation in myopic eyes with axial length of 26 mm or more that had undergone previous pars plana vitrectomy (PPV). METHODS:This prospective study comprised 37 highly m...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2010.6096
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of the ISNT rule in normal eyes of Koreans. METHODS:We retrospectively reviewed medical records of 890 subjects with fundus photographs and evaluated the presence of the cup and ISNT rule satisfaction. If the ISNT rule was violated, the quadrants in which the neuroretinal rim was thinn...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119876824
更新日期:2021-01-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000306
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:The aim of the present study was to evaluate the efficacy of diode laser cyclophotocoagulation (DCPC) and cyclocryotherapy (CCT) in the treatment of refractory glaucoma and compare the postoperative complications and discomfort rates. METHODS:In a prospective, randomized, controlled clinical study, 40 eyes of ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.5301/EJO.2011.6326
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Transforming growth factor-beta1 (TGF-beta1) is thought to play a pivotal role in the regulation of the wound healing process after glaucoma filtering surgery. The aim of the present study was to investigate whether platelet-derived growth factor isoforms (PDGF-AA, PDGF-BB), basic fibroblast growth factor (bFGF...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210001000203
更新日期:2000-04-01 00:00:00
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journal_title:European journal of ophthalmology
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abstract::The study investigated the pattern of the direct-current electroretinogram (ERG) of albino rabbits during prolonged intermittent recording, and whether different initial dark adaptation periods or starting the experiments at different times influenced the results. We examined 27 rabbits under general anesthesia, in th...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Strabismus fixus is a rare condition and usually is of convergent type in which one or both eyes are anchored in a position of extreme adduction. Convergent type strabismus fixus is considered to be a congenital disorder and a part of congenital extraocular muscle fibrosis syndrome. Villasecca and Martinez described a...
journal_title:European journal of ophthalmology
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更新日期:2003-03-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119845224
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To describe the surgical interventions in congenital pupillary-iris-lens membrane. Six patients with congenital pupillary-iris-lens membrane presented with partial or totally occluded pupils, or increased intraocular pressure (IOP). METHODS:We describe the value of creating 2 paracenteses. The first one is mad...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.7734
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:Complete epithelial wound healing is a milestone in early postoperative care after penetrating keratoplasty. The re-epithelialization rate after penetrating keratoplasty was measured in patients receiving a new matrix therapy agent (regenerating agent, Cacicol®) that mimics heparan sulphates. METHODS:This w...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:To report the first case of bilateral ocular decompression retinopathy after uneventful non-perforating deep sclerectomy with mitomycin C in a child with tubulointerstitial nephritis and uveitis syndrome. CASE DESCRIPTION:An 8-year-old girl affected by tubulointerstitial nephritis and uveitis syndrome dev...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To investigate visual function and ocular features in children with attention deficit hyperactivity disorder (ADHD). METHODS:Fifty-one children underwent a detailed ophthalmologic evaluation. Thirty-two were diagnosed with ADHD, and 19 children with attention deficit disorder (ADD). The mean age was 9.9±3.1 ye...
journal_title:European journal of ophthalmology
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更新日期:2012-11-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2017-01-19 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2007-11-01 00:00:00