Systemic bevacizumab for retinal angiomatous proliferation associated with retinal pigment epithelial detachment.

Abstract:

PURPOSE:To report the off-label use of systemic bevacizumab in a patient with stage 3 retinal angiomatous proliferation (RAP) associated with a vascularized pigmented epithelium detachment (PED). METHODS:Interventional case report. RESULTS:The patient was treated with systemic bevacizumab after obtaining fully informed consent. At 3 months post-treatment, the authors observed an improvement of one line (seven letters) in visual acuity and total regression of the PED on ocular coherence tomography. No adverse effects were observed. CONCLUSIONS:Systemic bevacizumab therapy appears to be safe and effective in the treatment of RAP associated with PED during this short follow-up period of 3 months. The authors recommend a large trial with long-term follow-up to confirm the promising results and evaluate the occurrence of adverse effects associated with systemic bevacizumab.

journal_name

Eur J Ophthalmol

authors

Abi-Ayad N,Mauget-Faysse M,Amara-Allieu S,Ardisson P

doi

10.1177/112067210701700621

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

987-91

issue

6

eissn

1120-6721

issn

1724-6016

journal_volume

17

pub_type

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