Abstract:
PURPOSE:To report the off-label use of systemic bevacizumab in a patient with stage 3 retinal angiomatous proliferation (RAP) associated with a vascularized pigmented epithelium detachment (PED). METHODS:Interventional case report. RESULTS:The patient was treated with systemic bevacizumab after obtaining fully informed consent. At 3 months post-treatment, the authors observed an improvement of one line (seven letters) in visual acuity and total regression of the PED on ocular coherence tomography. No adverse effects were observed. CONCLUSIONS:Systemic bevacizumab therapy appears to be safe and effective in the treatment of RAP associated with PED during this short follow-up period of 3 months. The authors recommend a large trial with long-term follow-up to confirm the promising results and evaluate the occurrence of adverse effects associated with systemic bevacizumab.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Abi-Ayad N,Mauget-Faysse M,Amara-Allieu S,Ardisson Pdoi
10.1177/112067210701700621subject
Has Abstractpub_date
2007-11-01 00:00:00pages
987-91issue
6eissn
1120-6721issn
1724-6016journal_volume
17pub_type
杂志文章abstract:PURPOSE:Reconstruction of the ocular surface is challenging. As an alternative to mucosal and limbal epithelial, we study the feasibility of cultivated human conjunctival epithelial (HCjE) cells of patients with total limbal stem cell deficiency (LSCD). METHODS:We studied superior forniceal conjunctival biopsies harve...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000511
更新日期:2014-11-06 00:00:00
abstract:PURPOSE:To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. METHODS:The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in vis...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6425
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. METHODS:194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:To assess the association between appearance of dissociated optic nerve fiber layer (DONFL) after internal limiting membrane (ILM) peeling and changes in the macular nerve fiber layer (NFL) area by spectral-domain optical coherence tomography (SD-OCT). METHODS:This study included 132 consecutive patients who h...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5001067
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To report a corneal transplant complication associated with intracameral recombinant tissue plasminogen activator (rTPA) treatment of postoperative fibrin reaction. METHODS:In a 71-year-old patient, a triple procedure was performed for perforated rheumatic ulcer and secondary cataract. RESULTS:A dense band ke...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700328
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:Characterize the safety and tolerability of lifitegrast ophthalmic solution 5.0% for the treatment of dry eye disease. METHODS:Pooled data from five randomized controlled trials were analyzed. Key inclusion criteria were adults with dry eye disease (Schirmer tear test score ⩾1 and ⩽10 mm, eye dryness score ⩾40...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1120672118791936
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:To look for ophthalmologic abnormalities in 15 patients with Wolfram syndrome, also known as DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness). METHODS:Fifteen patients from four inbred families diagnosed as having Wolfram syndrome at the National Center for Diabetes, Endocri...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200202
更新日期:2002-03-01 00:00:00
abstract:INTRODUCTION::The purpose of the study was to estimate the number of people with diabetes mellitus, the prevalence of diabetes mellitus and the prevalence of blindness and severe visual impairment among people with diabetes mellitus in Hungary based on our recent national representative survey. METHODS::Altogether 105...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/1120672118811738
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To compare diagnostic capabilities and agreement between Oculus-Spark perimetry and 3 procedures of glaucoma morphologic analysis. METHODS:A total of 102 normal eyes and 104 consecutive eyes with suspected or confirmed glaucoma (1 eye per subject) were analyzed in a prospective observational case-control study...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000233
更新日期:2013-05-01 00:00:00
abstract::Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120939388
更新日期:2020-07-02 00:00:00
abstract:PURPOSE:To identify a new cortical vitreous segmentation protocol for non invasive standardised investigation of Neovascularisation (NV) with detection of regression of NV activity in Proliferative Diabetic Retinopathy (PDR). DESIGN:Retrospective study. PARTICIPANTS:One hundred and eighty-six eyes of 93 consecutive d...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120944028
更新日期:2020-07-28 00:00:00
abstract:AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120929958
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To present a new indicator that measures the sulci of the lacrimal lake of the eye according to the degrees of ocular abduction at which they vanish. This new approach will help determine the severity and progression of mucosal retraction in ocular surface diseases. METHODS:A total of 181 eyes of 94 healthy pe...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100303
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:The objective of the study was to compare the intraocular pressure (IOP)-lowering efficacy and safety of travoprost 0.004%/timolol 0.5% ophthalmic solution (Trav/Tim) to latanoprost 0.005%/timolol 0.5% ophthalmic solution (Lat/Tim), dosed once daily in the morning, in patients with open-angle glaucoma (OAG) or ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/112067210701700206
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:Management of Graves' ophthalmopathy remains challenging. Over the last decade, previous studies have shown promising results for Rituximab in the treatment of Graves' ophthalmopathy. We present the response of 14 individuals with active moderate-to-severe Graves' ophthalmopathy to Rituximab, representing one o...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119845224
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To compare 2 different application methods of mitomycin C (MMC) in patients undergoing trabeculectomy. METHODS:This retrospective trial compared outcomes of 191 eyes that underwent trabeculectomy with small-area (96 eyes; 50.3%) and large-area (95 eyes; 49.7%) MMC application. Main outcome measures were chang...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000287
更新日期:2013-09-01 00:00:00
abstract::Idiopathic macular holes have long been considered to be a stable, untreatable condition with little or no chance of spontaneous visual improvement. Within the last few years, surgical intervention has been developed for the management of idiopathic Stage 3 and Stage 4 holes. With pars plana vitrectomy surgery, at lea...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract:PURPOSE::To describe the optical coherence tomography angiography characteristics of myopic patients with choroidal neovascularization secondary to pathologic myopia during ranibizumab therapy. METHODS::Nineteen patients were enrolled in this prospective study (13 females, 6 males, mean age 55.25 ± 9.63 years) for a t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118785495
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:Good binocular potential has been a fundamental defining characteristic of acute acquired concomitant esotropia (AACE) type II. The purpose of this study was to ascertain the clinical features and surgical outcome in children with AACE type II who underwent repeated surgery for the sake of binocularity. METHOD...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000301
更新日期:2010-05-01 00:00:00
abstract:SIGNIFICANCE:Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120924545
更新日期:2020-05-07 00:00:00
abstract:PURPOSE:To investigate the impact of diabetes mellitus-induced changes on intraocular pressure measurements using Goldmann applanation tonometry, Ocular Response Analyzer, and Corvis ST. METHODS:Measurements were done using Goldmann applanation tonometry, Ocular Response Analyzer, and Corvis ST in 69 diabetic patients...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119890517
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To describe the neuro-ophthalmic manifestations of patients with intracranial cavernous hemangiomas (cavernomas). METHODS:A retrospective review of all patients with intracranial cavernomas with neuroophthalmic manifestations who were treated at the Royal Adelaide Hospital in Australia between 1994 and 2004. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600124
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy, safety, and tolerability of Timogel® preservative-free once daily compared to timolol 0.5% ophthalmic solution bid in patients with ocular hypertension (OHT) and patients with primary open-angle glaucoma (POAG). METHODS:A total of 75 patients with OHT and patients with POAG treated wi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000006
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Traumatic eye injuries due to large foreign bodies (FB) are rare. The visual prognosis is often poor in these cases because of severe ocular damage. Staged surgical procedures with eventual enucleation or evisceration are often indicated. METHODS:Case series. RESULTS:The authors describe two patients with eye...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300413
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:This study was conducted in 2002-2003 at selected schools of eight health regions of Oman. The authors present risk factors and predictors of progression of myopia between the 7th and 10th grades. METHODS:This was a historical cohort study. A total of 1304 students in 10th grade, both with and without progress...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700115
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To correlate conjunctival intercellular adhesion molecule 1 (ICAM-1) expression with cytologic and clinical findings of chronic graft-versus-host disease (GVHD). METHODS:Seven patients with chronic GVHD-related keratoconjunctivitis and five age-matched normal controls were recruited for the study. Clinical exa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600104
更新日期:2006-01-01 00:00:00
abstract::We sent questionnaires to 424 retina specialists in order to compile information on the use of fluorescein angiography in pregnant women. Four-hundred and three specialists responded. Of these, 313 (78%) had never performed fluorescein angiography on a pregnant woman. Ninety specialists (22%) had performed at least on...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract:PURPOSE:To report optical coherence tomography (OCT) and retinal thickness analyzer (RTA) findings in a case of spontaneous resolution of vitreomacular traction syndrome. METHODS:Qualitative and quantitative analysis of the macular region was performed with OCT and RTA. RESULTS:In the left eye of a 34-year-old woman ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210401400113
更新日期:2004-01-01 00:00:00
abstract::Purpose. To compare long-term variability of retinal nerve fiber layer thickness (RNFLT) measurements made with the RTVue-100 Fourier-domain optical coherence tomograph (RTVue-OCT) and scanning laser polarimetry with variable (GDx-VCC) and enhanced (GDx-ECC) corneal compensation. Methods. One eye each of 110 Caucasian...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000178
更新日期:2013-01-21 00:00:00
abstract:PURPOSE:To examine the nature and frequency of ocular side effects due to systemic target therapy with BRAF and MEK inhibitors as well as immunotherapy with cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) monoclonal antibodies used in the treatment of cutaneous malignant melanoma (CMM). DE...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120930688
更新日期:2020-05-31 00:00:00