Familial inflammatory inclusion body myositis.

abstract：:In order to evaluate the incidence and aetiology of hypergastrinaemia 53 patients with seropositive rheumatoid arthritis were examined for gastric acid secretion, fasting serum gastrin concentration, circulating parietal cell antibodies, and some parameters of the activity of inflammation of rheumatoid arthritis. The ...

journal_title：Annals of the rheumatic diseases

authors： de Witte TJ,Geerdink PJ,Lamers CB,Boerbooms AM,van der Korst JK

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVE:To investigate the elastic properties of the ascending aorta in untreated patients with giant cell arteritis compared with age and sex matched normal controls. METHODS:Distensibility of the ascending aorta and aortic strain were measured in 22 patients with a recent diagnosis of giant cell arteritis (documen...

journal_title：Annals of the rheumatic diseases

authors： Margos PN,Moyssakis IE,Tzioufas AG,Zintzaras E,Moutsopoulos HM

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:To assess the association of body mass index (BMI) with modifiable cardiovascular disease (CVD) risk factors in patients with rheumatoid arthritis (RA). METHODS:BMI, disease activity, selected CVD risk factors and CVD medication were assessed in 378 (276 women) patients with RA. Patients exceeding accepted ...

journal_title：Annals of the rheumatic diseases

authors： Stavropoulos-Kalinoglou A,Metsios GS,Panoulas VF,Douglas KM,Nevill AM,Jamurtas AZ,Kita M,Koutedakis Y,Kitas GD

更新日期：2009-02-01 00:00:00

abstract：:We report two patients with systemic lupus erythematosus who subsequently developed thrombotic thrombocytopenic purpura. In each case the coexistence of these two conditions was confirmed by pathological findings. Both patients responded to treatment, but one eventually died. A review of the literature suggests a poss...

journal_title：Annals of the rheumatic diseases

authors： Fox DA,Faix JD,Coblyn J,Fraser P,Smith B,Weinblatt ME

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:Notch signalling pathways are critical for angiogenesis and endothelial cell (EC) fate; however the mechanisms regulating these processes in the inflamed joint remain to be elucidated. Here, we examine whether Notch signalling mediates vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang2)-induce...

journal_title：Annals of the rheumatic diseases

authors： Gao W,Sweeney C,Walsh C,Rooney P,McCormick J,Veale DJ,Fearon U

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The aim of the study was to better characterise the immunological origin and the behaviour of interleukin (IL)-23-responsive innate lymphoid cells (ILCs) in the gut, synovial fluid (SF) and bone marrow (BM) of patients with ankylosing spondylitis (AS). METHODS:ILC1, ILC2 and ILC3 cells were determined and c...

journal_title：Annals of the rheumatic diseases

authors： Ciccia F,Guggino G,Rizzo A,Saieva L,Peralta S,Giardina A,Cannizzaro A,Sireci G,De Leo G,Alessandro R,Triolo G

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The study aimed to evaluate the use of positron emission tomography/computed tomography (PET/CT) with (68)Ga-PRGD2 as the tracer for imaging of synovial angiogenesis in patients with rheumatoid arthritis (RA). METHODS:Twenty untreated active patients with RA underwent (68)Ga-PRGD2 PET/CT and (18)F-FDG PET/C...

journal_title：Annals of the rheumatic diseases

authors： Zhu Z,Yin Y,Zheng K,Li F,Chen X,Zhang F,Zhang X

更新日期：2014-06-01 00:00:00

abstract：:Arthro-osteitis at the anterior chest wall was found in 12 (9.4%) out of 128 consecutive patients with pustulosis palmaris et plantaris. This finding indicates that the concomitance of arthro-osteitis with PPP is not incidental but is based on some common aetiological factor. We propose a term ;pustulotic arthro-ostei...

journal_title：Annals of the rheumatic diseases

authors： Sonozaki H,Kawashima M,Hongo O,Yaoita H,Ikeno M,Matsuura M,Okai K,Azuma A

更新日期：1981-12-01 00:00:00

abstract：:Fourteen patients with cystic fibrosis arthritis and eight patients with cystic fibrosis and hypertrophic osteoarthropathy were typed for HLA-A, B, C, DR, and DQ antigens and were compared with age and sex matched controls with cystic fibrosis. The diagnosis of cystic fibrosis arthritis and hypertrophic osteoarthropat...

journal_title：Annals of the rheumatic diseases

authors： Rush PJ,Gladman DD,Shore A,Anhorn KA

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:Evidence suggests that doxycycline might have disease-modifying properties in osteoarthritis. However, the clinically relevant question as to whether doxycycline also modifies symptoms in knee osteoarthritis is unanswered. The objective of this study was to investigate the effectiveness of doxycycline on pai...

journal_title：Annals of the rheumatic diseases

authors： Snijders GF,van den Ende CH,van Riel PL,van den Hoogen FH,den Broeder AA,NOAC study group.

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Antibodies directed against citrullinated proteins (eg anti-cyclic citrullinated peptide (CCP)) have excellent diagnostic and good prognostic potential for rheumatoid arthritis. Type 1 autoimmune hepatitis (AIH-1) is a chronic liver disease characterised by a variety of serum autoantibodies. Recently, in a l...

journal_title：Annals of the rheumatic diseases

authors： Vannini A,Cheung K,Fusconi M,Stammen-Vogelzangs J,Drenth JP,Dall'Aglio AC,Bianchi FB,Bakker-Jonges LE,van Venrooij WJ,Pruijn GJ,Zendman AJ

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the contribution of polymorphisms in the vitamin D receptor (VDR) gene to ethnic variations in bone mass in mother and children from different ethnic origins. METHODS:VDR genotypes and bone mass in 43 African-American and white women, mean age 38.2 years, and 41 of their children were studied. Al...

journal_title：Annals of the rheumatic diseases

authors： Nelson DA,Vande Vord PJ,Wooley PH

更新日期：2000-08-01 00:00:00

abstract：:Chemotactic migration of leucocytes largely depends on adhesive interaction with the substratum and recognition of a chemoattractant gradient. Both aspects, cell adhesion and chemotaxis, are regulated by members of the family of chemotactic cytokines (chemokines) comprising structurally related and secreted proteins o...

journal_title：Annals of the rheumatic diseases

authors： Moser B,Willimann K

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To assess the effects of acute stress on inflammatory, haemostatic, rheological, and haemodynamic activity in patients with rheumatoid arthritis (RA) in comparison with patients with osteoarthritis (OA). METHODS:21 patients with RA and 10 with OA underwent a brief mental stress task while standing. Inflammat...

journal_title：Annals of the rheumatic diseases

authors： Veldhuijzen van Zanten JJ,Ring C,Carroll D,Kitas GD

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Small studies have linked α1 antitrypsin (α1AT) deficiency to patients with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV). OBJECTIVE:To test the validity and the mechanism of this association between α1AT and AAV. METHODS:The distribution of α1AT deficiency alleles Z and S was co...

journal_title：Annals of the rheumatic diseases

authors： Morris H,Morgan MD,Wood AM,Smith SW,Ekeowa UI,Herrmann K,Holle JU,Guillevin L,Lomas DA,Perez J,Pusey CD,Salama AD,Stockley R,Wieczorek S,McKnight AJ,Maxwell AP,Miranda E,Williams J,Savage CO,Harper L

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:To further evaluate the role of bacterial antigens in triggering inflammation in the joint in patients with reactive arthritis by studying local antibody synthesis in the joint. METHODS:Yersinia-specific antibodies in paired serum and synovial fluid samples from 29 patients with yersinia triggered reactive ...

journal_title：Annals of the rheumatic diseases

authors： Mäki-Ikola O,Lahesmaa R,Heesemann J,Merilahti-Palo R,Saario R,Toivanen A,Granfors K

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVES:To show whether intra-articular steroid injections are effective in osteoarthritis; to determine factors that predict response; and to determine whether injection has a beneficial effect on muscle strength. METHODS:Double blind, placebo controlled, crossover study in 59 patients with symptomatic osteoarthri...

journal_title：Annals of the rheumatic diseases

authors： Jones A,Doherty M

更新日期：1996-11-01 00:00:00

abstract：:Quantitative isotype specific enzyme linked immunosorbent assay (ELISA) was used to determine the distribution of immunoglobulin isotypes and phospholipid specificities of anticardiolipin (anti-CL) antibodies in 40 patients with one or more of the following 'antiphospholipid (anti-PL) antibody associated clinical comp...

journal_title：Annals of the rheumatic diseases

authors： Gharavi AE,Harris EN,Asherson RA,Hughes GR

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether type II collagen (CII) is recognised by oligoclonally expanded synovial T cells of patients with rheumatoid arthritis (RA). METHODS:Peripheral blood mononuclear cells (PBMC) from 15 RA patients were stimulated with CII in vitro. T cell clones expanded by such stimulation were compared ...

journal_title：Annals of the rheumatic diseases

authors： Sekine T,Kato T,Masuko-Hongo K,Nakamura H,Yoshino S,Nishioka K,Yamamoto K

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To examine the effects of smoking on cartilage loss and pain at the knee in individuals with knee osteoarthritis. METHODS:159 men with symptomatic knee osteoarthritis who participated in a 30-month, prospective, natural history study of knee osteoarthritis were examined. The more symptomatic knee was imaged ...

journal_title：Annals of the rheumatic diseases

authors： Amin S,Niu J,Guermazi A,Grigoryan M,Hunter DJ,Clancy M,LaValley MP,Genant HK,Felson DT

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Factors contributing to the development of systemic lupus erythematosus (SLE) remain largely unknown although are likely to include both environmental and genetic components. Studies on murine lupus have indicated a role for an antibody that blocks binding of cytotoxic T lymphocyte associated-4 (CTLA-4) to B...

journal_title：Annals of the rheumatic diseases

authors： Heward J,Gordon C,Allahabadia A,Barnett AH,Franklyn JA,Gough SC

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:The recombinant zoster vaccine (RZV) containing a strong non-aluminium adjuvant is associated with increased risk of gout flares, presumably via NLRP3 inflammasome activation. We tested the possibility that other vaccines may also be associated with gout flares. METHODS:We conducted an online case-crossover...

journal_title：Annals of the rheumatic diseases

authors： Yokose C,McCormick N,Chen C,Neogi T,Chaisson C,Terkeltaub R,Hunter DJ,Zhang Y,Choi H

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:The relationship between radiographic evidence of osteoarthritis and knee pain has been weak. This may be because features that best discriminate knees with pain have not been included in analyses. We tested the correlation between knee pain and radiographic features taking into account both image analysis f...

journal_title：Annals of the rheumatic diseases

authors： Minciullo L,Parkes MJ,Felson DT,Cootes TF

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Vascular damage is a key pathological process in systemic sclerosis (SSc) and accounts for significant disease-related morbidity. To determine the clinical burden of severe digital vasculopathy (SDV), we have reviewed hospital-based treatment for this important complication of SSc in a large single centre co...

journal_title：Annals of the rheumatic diseases

authors： Nihtyanova SI,Brough GM,Black CM,Denton CP

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To investigate the efficacy and safety of peficitinib, an oral Janus kinase inhibitor, in patients with rheumatoid arthritis (RA). METHODS:In this double-blind phase III study, patients with RA and an inadequate response to prior disease-modifying anti-rheumatic drugs (DMARDs) were randomised to peficitinib...

journal_title：Annals of the rheumatic diseases

authors： Tanaka Y,Takeuchi T,Tanaka S,Kawakami A,Iwasaki M,Song YW,Chen YH,Wei JC,Lee SH,Rokuda M,Izutsu H,Ushijima S,Kaneko Y,Akazawa R,Shiomi T,Yamada E

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The molecular mechanisms of syndesmophyte formation in ankylosing spondylitis (AS) are yet to be characterised. Molecules involved in bone formation such as Wnt proteins and their antagonists probably drive syndesmophyte formation in AS. METHODS:This study investigated sequential serum levels of functiona...

journal_title：Annals of the rheumatic diseases

authors： Heiland GR,Appel H,Poddubnyy D,Zwerina J,Hueber A,Haibel H,Baraliakos X,Listing J,Rudwaleit M,Schett G,Sieper J

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the risk of septic arthritis (SA) in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor (TNF) therapy. METHODS:Using data from the British Society for Rheumatology Biologics Register, a prospective observational study, the authors compared the risk of SA between 11 ...

journal_title：Annals of the rheumatic diseases

authors： Galloway JB,Hyrich KL,Mercer LK,Dixon WG,Ustianowski AP,Helbert M,Watson KD,Lunt M,Symmons DP,BSR Biologics Register.

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Myeloid inhibitory C-type lectin-like receptor (MICL, Clec12A) is a C-type lectin receptor (CLR) expressed predominantly by myeloid cells. Previous studies have suggested that MICL is involved in controlling inflammation. OBJECTIVE:To determine the role of this CLR in inflammatory pathology using Clec12A(-/...

journal_title：Annals of the rheumatic diseases

authors： Redelinghuys P,Whitehead L,Augello A,Drummond RA,Levesque JM,Vautier S,Reid DM,Kerscher B,Taylor JA,Nigrovic PA,Wright J,Murray GI,Willment JA,Hocking LJ,Fernandes MJ,De Bari C,Mcinnes IB,Brown GD

更新日期：2016-07-01 00:00:00

abstract：:The effect of immune complexes (IC) isolated from systemic lupus erythematosus (SLE) sera with polyethylene glycol and gel filtration on the chemotaxis and Fc receptor function of healthy monocytes was examined. Even at a low protein concentration (1 microgram/ml = 1 mg/l) ICs inhibit monocyte chemotaxis. ICs from pat...

journal_title：Annals of the rheumatic diseases

authors： Lukács K,Kávai M,Bányai A,Sonkoly I,Végh E,Szabó G,Szegedi G

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:In 2001, the European League Against Rheumatism developed and disseminated the first guidelines for musculoskeletal (MS) ultrasound (US) in rheumatology. Fifteen years later, the dramatic expansion of new data on MSUS in the literature coupled with technological developments in US imaging has necessitated an...

journal_title：Annals of the rheumatic diseases

authors： Möller I,Janta I,Backhaus M,Ohrndorf S,Bong DA,Martinoli C,Filippucci E,Sconfienza LM,Terslev L,Damjanov N,Hammer HB,Sudol-Szopinska I,Grassi W,Balint P,Bruyn GAW,D'Agostino MA,Hollander D,Siddle HJ,Supp G,Schmidt W

更新日期：2017-12-01 00:00:00