Abstract:
:The aqueous extract of whole plant of Coronopus didymus LINN (CD) [Family: Bracicacea] was screened for antiallergic, antipyretic and hepatoprotective effects in rats and hypoglycemic activity in mice. The extract showed significant antiallergic, antipyretic, hypoglycemic and hepatoprotective activity at 200 and 400 mg/kg doses on oral administration. Mechanistically, CD acts as an antioxidant as evidenced by its ability to scavenge DPPH and superoxide radicals. All the observed activities may be due to the presence of flavonoids, saponins and tannins as they are reported to possess a variety of biological activities.
journal_name
Biol Pharm Bulljournal_title
Biological & pharmaceutical bulletinauthors
Mantena SK,Mutalik S,Srinivasa H,Subramanian GS,Prabhakar KR,Reddy KR,Srinivasan KK,Unnikrishnan MKdoi
10.1248/bpb.28.468subject
Has Abstractpub_date
2005-03-01 00:00:00pages
468-72issue
3eissn
0918-6158issn
1347-5215pii
JST.JSTAGE/bpb/28.468journal_volume
28pub_type
杂志文章abstract::The purpose of this study was to evaluate the influence of caffeine and theophylline on the development of dental caries in rats. Six Wistar dams (spf), mutans streptococci free, were obtained, each with six male pups. The dams were infected by Streptococcus sobrinus 6715 and divided into three groups which received d...
journal_title:Biological & pharmaceutical bulletin
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journal_title:Biological & pharmaceutical bulletin
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