Abstract:
OBJECTIVE:Although antimony electrodes are by far the most popular for performing oesophageal pH monitoring, there are few data comparing the accuracy of glass and antimony electrodes. Therefore, we tested the accuracy of both electrodes in the prediction of oesophagitis. METHOD:pH monitoring using a glass electrode and an antimony electrode was performed in 60 distressed infants, aged between 1 and 6 months. An upper endoscopy with oesophageal biopsies was also performed in all infants. RESULTS:A reflux index (percentage of the total time with pH < 4.0) greater than 5% was considered to be abnormal and was found in 40/60 patients. Histological oesophagitis was present in 26/60 infants. The reflux index was > 5% with the glass electrode in 18/26 children with histological oesophagitis and with the antimony electrode in 10/26 children with histological oesophagitis. Histology of the oesophagus was normal in 22/40 children with abnormal pH monitoring. With the glass electrode, the mean reflux index in the group with oesophagitis was significantly higher than in the group with normal histology, although there was an important overlap. With the antimony electrode, the mean reflux indices in the groups with and without oesophagitis were not different. Regarding normal/abnormal, there was discordance in 35% of the pH studies. No reflux index could be related to a clinically useful sensitivity and specificity to predict oesophagitis. CONCLUSION:The reflux index does not accurately predict oesophagitis. Oesophageal pH monitoring and endoscopy provide complementary information.
journal_name
Eur J Gastroenterol Hepatoljournal_title
European journal of gastroenterology & hepatologyauthors
Vandenplas Y,Badriul H,Verghote M,Hauser B,Kaufman Ldoi
10.1097/00042737-200412000-00015subject
Has Abstractpub_date
2004-11-01 00:00:00pages
1325-30issue
12eissn
0954-691Xissn
1473-5687pii
00042737-200412000-00015journal_volume
16pub_type
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
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journal_title:European journal of gastroenterology & hepatology
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更新日期:2017-03-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
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更新日期:2005-04-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
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pub_type: 杂志文章
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doi:10.1097/MEG.0b013e32825a6ab4
更新日期:2007-10-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1097/MEG.0b013e32831bc400
更新日期:2009-06-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1097/MEG.0b013e3282f172fa
更新日期:2008-06-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2010-11-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/00042737-200104000-00017
更新日期:2001-04-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
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更新日期:1999-02-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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更新日期:2015-03-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0000000000000380
更新日期:2015-08-01 00:00:00
abstract::Primary malignant lymphoma of the bowel is a rare complication of inflammatory bowel disease. The association of gastrointestinal lymphoma, inflammatory bowel disease and prior immunosuppression remains unclear. We report the first case of azathioprine-treated ulcerative colitis developing rectal lymphoma. ...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-200108000-00022
更新日期:2001-08-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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更新日期:1996-10-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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更新日期:2009-12-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0000000000000739
更新日期:2017-01-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-199910000-00017
更新日期:1999-10-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-199811000-00011
更新日期:1998-11-01 00:00:00