Abstract:
:Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identified by chromosome banding analysis and confirmed by fluorescence in situ hybridization analysis of interphase cells. Because of the rarity of these changes, possible molecular mechanisms associated with this karyotype are discussed.
journal_name
Int J Hematoljournal_title
International journal of hematologyauthors
Hsiao HH,Hung YH,Hsiao HP,Tseng SB,Tsai HJ,Liu YC,Liu TC,Chao MC,Chang Y,Lin SFdoi
10.1532/ijh97.a10323subject
Has Abstractpub_date
2004-11-01 00:00:00pages
351-3issue
4eissn
0925-5710issn
1865-3774journal_volume
80pub_type
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