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Heterocyclic sulfoxide and sulfone inhibitors of fatty acid amide hydrolase.

Abstract：

:A novel series of heterocyclic sulfoxides and sulfones was prepared and examined as potential inhibitors of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of neuromodulating fatty acid amides including anandamide and oleamide.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Du W,Hardouin C,Cheng H,Hwang I,Boger DL

doi

10.1016/j.bmcl.2004.10.025

subject

Has Abstract

pub_date

2005-01-03 00:00:00

pages

103-6

issue

1

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(04)01253-3

journal_volume

15

pub_type

杂志文章

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