Hypereosinophilic syndrome resembling chronic inflammatory bowel disease with primary sclerosing cholangitis.

abstract：:A 69-year old woman suffered from severe dysphagia, abdominal pain, and weight loss. The dysphagia was accompanied by nasal speech, nasal regurgitation of food, weakness, and wasting of the proximal muscles of the upper and lower girdles. Laboratory data revealed T3 sephadex uptake 65.2%; T4 15.1 mcg%; and T3 250 ng%....

journal_title：Journal of clinical gastroenterology

authors： Branski D,Levy J,Globus M,Aviad I,Keren A,Chowers I

更新日期：1984-10-01 00:00:00

abstract：:In advanced cirrhosis and hepatorenal syndrome, peripheral vasodilation is a prominent feature and may be pathophysiologically relevant. To determine whether the potent vasodilator, calcitonin gene-related peptide (CGRP), circulates at abnormal levels in patients with these disorders, we observed eight patients with a...

journal_title：Journal of clinical gastroenterology

authors： Gupta S,Morgan TR,Gordan GS

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Diverticular disease (DD) is a common gastrointestinal inflammatory disorder associated with an enteric neuropathy. Although enteric glial cells (EGCs) are essential regulators of intestinal inflammation and motility functions, their contribution to the pathophysiology of DD remains unclear. Therefore, we an...

journal_title：Journal of clinical gastroenterology

authors： Cossais F,Leuschner S,Barrenschee M,Lange C,Ebsen M,Vogel I,Böttner M,Wedel T

更新日期：2019-07-01 00:00:00

abstract：GOALS:To review the published experience with acute pancreatitis in childhood. STUDY:Computerized search of the English medical literature since 1965 using MEDLINE. RESULTS:Details of 589 patients were reviewed. Mean age was 9.2 +/- 2.4 years (range: 1 week to 21 years). Male to female ratio was 1.2. Etiologies inclu...

journal_title：Journal of clinical gastroenterology

authors： Benifla M,Weizman Z

更新日期：2003-08-01 00:00:00

abstract：GOAL:To study the rate at which Helicobacter pylori infection is treated in an immigrant cohort after diagnosis by esophagogastroduodenoscopy (EGD). BACKGROUND:Gastric cancer is the second leading cause of cancer death worldwide, and is especially prevalent in East Asia; immigrants from this part of the world remain a...

journal_title：Journal of clinical gastroenterology

authors： Cho A,Chaudhry A,Minsky-Primus L,Tso A,Perez-Perez G,Diehl DL,Marcus SG,Gany FM

更新日期：2006-01-01 00:00:00

abstract：:The use of probiotics in diarrheal diseases of children is increasing. Probiotics, mostly lactic acid bacteria such as Lactobacilli and Bifidobacteria, but also the yeast Saccharomyces boulardii, have been tried in many double-blinded, randomized, placebo-controlled studies, and several well-conducted meta-analyses ar...

journal_title：Journal of clinical gastroenterology

authors： Guandalini S

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Although sessile serrated adenomas (SSAs) may represent a separate and important pathway for colorectal cancer (CRC), little is known about the risk factors for these lesions. Molecular abnormalities such as BRAF have been observed in SSA and smokers. Our hypothesis is that smoking may be associated with the...

journal_title：Journal of clinical gastroenterology

authors： Anderson JC,Rangasamy P,Rustagi T,Myers M,Sanders M,Vaziri H,Wu G,Birk JW,Protiva P

更新日期：2011-09-01 00:00:00

abstract：:A patient with Crohn's disease developed acute pancreatitis 4 h after retaking one 50 mg dose of orally administered 6-mercaptopurine (6-MP). All seven previously reported patients who were rechallenged with 50 mg or more of 6-MP developed pancreatitis within 48 h. These findings suggest that 6-MP can produce pancreat...

journal_title：Journal of clinical gastroenterology

authors： Cappell MS,Das KM

更新日期：1989-12-01 00:00:00

abstract：:We have seen three patients with acute ulcerative colitis after hydrogen peroxide enemas. The colitis is probably the result of the explosive entrance of gas into the loose connective tissues of the mucosa and submucosa of the rectum and sigmoid. Fortunately, it is transitory in nature, but it should be distinguished ...

journal_title：Journal of clinical gastroenterology

authors： Meyer CT,Brand M,DeLuca VA,Spiro HM

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Duodenal intraepithelial lymphocytosis (D-IEL) is an early marker for celiac disease (CD). However, the majority of cases are due to non-CD-related conditions. GOALS:To identify the predictors of CD when presented with D-IEL. METHODS:A total of 215 adult patients with D-IEL had undergone prospective and sy...

journal_title：Journal of clinical gastroenterology

authors： Aziz I,Key T,Goodwin JG,Sanders DS

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The cure for hepatitis B is defined as the hepatitis B surface antigen (HBsAg) seroclearance and/or seroconversion. Predictors of spontaneous seroconversion are not well described. The objective of this study is to identify predictors of spontaneous HBsAg seroconversion from community practice. METHODS:We p...

journal_title：Journal of clinical gastroenterology

authors： Wu CF,Fong TM,Wu SS,Saab S

更新日期：2020-07-01 00:00:00

abstract：:Various esophageal functional abnormalities have been described in patients with Barrett's esophagus (BE). A significantly higher esophageal acid exposure especially in the supine position has been documented in BE, as compared with the other gastroesophageal reflux disease phenotypes. In addition, weakly acidic reflu...

journal_title：Journal of clinical gastroenterology

authors： Fass R,Teramoto O,Kurin M,Khalessi A,Kitayama Y,Shibli F

更新日期：2020-07-01 00:00:00

abstract：:The intensity of diagnostic workup of patients with human immunodeficiency virus (HIV)-related chronic diarrhea is controversial. In the ideal setting in which an enteric pathogen is detected with minimal evaluation (stool tests) and in which specific treatment clears the diarrhea, eradicates the pathogen, and improve...

journal_title：Journal of clinical gastroenterology

authors： Rabeneck L

更新日期：1993-04-01 00:00:00

abstract：:Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu disease, is an hereditary disorder that results in fibrovascular dysplasia with the development of telangiectasias and arteriovenous malformations. It predominantly involves the skin, mucous membranes, viscera, lungs, and brain. Hereditary he...

journal_title：Journal of clinical gastroenterology

authors： Larson AM

更新日期：2003-02-01 00:00:00

abstract：:A 2-year-old boy presented with sexual precocity secondary to a hormone-producing hepatoblastoma. The tumor demonstrated an aggressive histologic pattern and stained immunohistochemically for alpha-fetoprotein and beta-subunit human chorionic gonadotrophin. After a successful liver transplant these tumor markers were ...

journal_title：Journal of clinical gastroenterology

authors： Heimann A,White PF,Riely CA,Ritchey AK,Flye MW,Barwick KW

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Gastrointestinal angiodysplasias (GIAD) are commonly diagnosed in the small bowel but can be located in other areas of the gastrointestinal tract. About half of patients diagnosed with GIAD have more than 1 lesion and 20% of patients have GIAD in both the small bowel and a source outside of the small bowel (...

journal_title：Journal of clinical gastroenterology

authors： Mai SH,Chao DC,Liao SY,Jackson CS

更新日期：2018-09-01 00:00:00

abstract：GOALS AND BACKGROUND:Nearly 40% of cytochrome P450 3A (CYP3A) activity is located in the small intestine. An earlier study has shown that cirrhotics with transjugular intrahepatic portosystemic shunts (TIPS) have diminished intestinal CYP3A activity. We hypothesized that oral CYP3A substrates known to prolong QT interv...

journal_title：Journal of clinical gastroenterology

authors： Vuppalanchi R,Juluri R,Ghabril M,Kim S,Thong N,Gorski JC,Chalasani N,Hall SD

更新日期：2011-08-01 00:00:00

abstract：:One patient's story is recounted. Relatively asymptomatic for 20 years, the patient reflects on factors that contributed to his healing. Psychosocial and spiritual dimensions are described as well as biomedical aspects. The story concludes that dealing with Crohn's disease triggered a spiritual quest which in turn con...

journal_title：Journal of clinical gastroenterology

authors： Sheehan DR

更新日期：1998-06-01 00:00:00

abstract：GOALS:We compare bowel cleanliness in patients taking same-day versus split-dose 4-L polyethylene glycol laxative for afternoon colonoscopy. Secondary objectives included patient satisfaction, adverse effects and patient tolerability. BACKGROUND:Afternoon colonoscopies have been associated with inadequate bowel prepar...

journal_title：Journal of clinical gastroenterology

authors： Castro FJ,Al-Khairi B,Singh H,Mohameden M,Tandon K,Lopez R

更新日期：2019-11-01 00:00:00

abstract：GOALS:Assess acceptance and attitudes regarding telemanagement (HAT) in patients with inflammatory bowel disease (IBD). BACKGROUND:Noncompliance is a barrier to successful outcomes in patients with IBD. Novel methods for monitoring and assessing compliance are needed. STUDY:HAT consists of a laptop connected to a wei...

journal_title：Journal of clinical gastroenterology

authors： Cross RK,Arora M,Finkelstein J

更新日期：2006-03-01 00:00:00

abstract：:Helicobacter pylori infects only human gastric epithelium, causes gastritis, and is strongly associated with gastroduodenal ulceration and gastric cancer. Colonization of the stomach with H. pylori is accompanied in the acute stage by an increased number of neutrophils in the lamina propria, indicative of gastric infl...

journal_title：Journal of clinical gastroenterology

authors： Nakajima N,Kuwayama H,Ito Y,Iwasaki A,Arakawa Y

更新日期：1998-01-01 00:00:00

abstract：:We describe the clinical course and outcome of Rwandan refugees with cholera-like illness (n = 567) and clinical dysentery (n = 1,062) treated at the Israeli Army field hospital in the disaster region of Goma, Zaire, during the summer of 1994. Vigorous fluid administration was the primary therapy, complemented with an...

journal_title：Journal of clinical gastroenterology

authors： Heyman SN,Ginosar Y,Shapiro M,Kluger Y,Marx N,Maayan S

更新日期：1997-12-01 00:00:00

abstract：:Juvenile chronic pancreatitis presenting with painless obstructive jaundice is extremely rare. Pancreatic disease in association with multiple somatic abnormalities presenting in late childhood is uncommon. We report such a case. ...

journal_title：Journal of clinical gastroenterology

authors： Isaacs JD,Keshavarzian A,Blumgart LH,Hodgson HJ

更新日期：1985-12-01 00:00:00

abstract：GOALS:To determine the proportion of patients with gastroesophageal reflux disease who are on proton pump inhibitors (PPIs) who could reduce their prior dosage by half, and identify predictors of successful step-down. BACKGROUND:Appropriate hypergastrinemia results from gastric acid inhibition. A gender difference in ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Metz DC,Lund SH,Gizurarson S,Jacobsen EI,Asgeirsdóttir GA,Yngadóttir Y,Björnsson ES

更新日期：2017-07-01 00:00:00

abstract：:Forty-five polyps were encountered at duodenoscopy between 1973 and 1978. Upper gastrointestinal x-rays were helpful in 25 patients, 13 of whom had duodenal polyps and 12 duodenal deformity or mass lesions. Polyps in 23 patients were larger than 1 cm in size. Biopsies were done in 38 patients; in 19 there was only nor...

journal_title：Journal of clinical gastroenterology

authors： Reddy RR,Schuman BM,Priest RJ

更新日期：1981-06-01 00:00:00

abstract：:We assessed the clinical and biochemical parameters associated with the development of posttransplantation diabetes (PTDM) in 52 liver transplant recipients followed up for 1 year. Diabetes was present before transplantation in 9.6% (5 of 52) of patients, and PTDM occurred in 23% (11 of 47) of the remaining liver tran...

journal_title：Journal of clinical gastroenterology

authors： Knobler H,Stagnaro-Green A,Wallenstein S,Schwartz M,Roman SH

更新日期：1998-01-01 00:00:00

abstract：:Sjogren syndrome (SS) is an autoimmune disease that affects exocrine glands and therefore may affect the gastrointestinal system, from the mouth, esophagus, and bowel to the liver and pancreas. Oral involvement in SS is mainly characterized by dryness, with a wide spectrum of symptoms, from mild-to-severe xerostomia w...

journal_title：Journal of clinical gastroenterology

authors： Ebert EC

更新日期：2012-01-01 00:00:00

abstract：:It is becoming increasingly recognized that purely clinical endpoints may not be sufficient in the treatment of patients with inflammatory bowel disease. As such, mucosal disease assessment has become a prominent component of the majority of recent clinical trials in Crohn's disease and ulcerative colitis. There is mo...

journal_title：Journal of clinical gastroenterology

authors： Osterman MT

更新日期：2013-03-01 00:00:00

abstract：:Celiac disease (CD) is the most common autoimmune enteropathy, triggered by a deregulated immune response to gliadin. It has been hypothesized that human intestinal microbiota may interfere with the pathogenesis of the disease and in the clinical course of CD. In the present review, we analyzed the microbiota alterati...

journal_title：Journal of clinical gastroenterology

authors： Losurdo G,Principi M,Iannone A,Ierardi E,Di Leo A

更新日期：2016-11-01 00:00:00

abstract：GOALS:To understand the degree to which psychosocial factors were preventing veterans with chronic hepatitis C virus from being eligible for antiviral treatment. BACKGROUND:Nearly 2% of the US population is infected with hepatitis C. Antiviral treatment requires substantial adherence despite challenging side effects. ...

journal_title：Journal of clinical gastroenterology

authors： Rowan PJ,Tabasi S,Abdul-Latif M,Kunik ME,El-Serag HB

更新日期：2004-07-01 00:00:00