Abstract：
BACKGROUND AND AIMS:Inpatients developing upper gastrointestinal (GI) haemorrhage are at increased risk of death. This study was performed to elucidate differences in inpatients and outpatients. PATIENTS/METHODS:Three hundred and sixty-two patients who needed esophagogastroduodenoscopy for upper GI bleeding were identified from endoscopy charts. Patients' characteristics, bleeding parameters, clinical presentation, pre-existing medication, and laboratory data were compared between patients who were admitted because of upper GI bleeding and patients who developed bleeding while in hospital for other reasons. RESULTS/FINDINGS:Hospital mortality was 39.0% in inpatients vs. 11.1% in outpatients (p<0.01). Death due to bleeding was observed in 9.5% of inpatients vs. 2.5% of outpatients (p<0.01). Whereas peptic ulcer was the most common source of bleeding in both, variceal bleeding was the most common cause of death because of haemorrhage in both. Recurrent bleeding was associated with mortality in outpatients (p<0.001), but not in inpatients (p=0.11). Rates of bleeding recurrence and need for surgery was similar in both groups. Inpatients suffered more often from renal disease, pulmonary disease, diabetes mellitus, coagulopathy, or immunosuppression, and were treated more frequently with acetylsalicylic acid, glucocorticoids and heparin. The frequency of pre-existing disease was higher in inpatients. INTERPRETATION/CONCLUSION:Higher mortality after GI bleeding in inpatients than in outpatients is due to a generally higher prevalence of co-morbidity rather than a single or a few risk factors.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Klebl FH,Bregenzer N,Schöfer L,Tamme W,Langgartner J,Schölmerich J,Messmann Hdoi
10.1007/s00384-004-0642-0subject
Has Abstractpub_date
2005-07-01 00:00:00pages
368-75issue
4eissn
0179-1958issn
1432-1262journal_volume
20pub_type
杂志文章abstract：PURPOSE:Bilobar colorectal liver metastases (CRLM) are often considered incurable or associated with poor prognosis even after R0 resection. In this single-center study, we evaluate the impact of CRLM spreading on recurrence-free survival (RFS) and cancer-specific overall survival (CSS) after R0 resection of CRLM with ...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-012-1455-1
更新日期：2012-10-01 00:00:00
abstract：INTRODUCTION:Rectal cancer is a frequently diagnosed tumor worldwide. Various studies have shown the noninferiority or even slight superiority of laparoscopic resection. However, there is no clear recommendation on whether age should influence the choice of surgical approach. MATERIALS AND METHODS:This study compared ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-019-03265-7
更新日期：2019-05-01 00:00:00
abstract：:Disruption of the anal sphincter results from obstetric injury, ano-rectal operations or external trauma. Obstetric or surgical division of the sphincteric mechanism may not be immediately apparent and the clinical presentation of incontinence may occur several years later [1, 2]. Reconstruction of the sphincter using...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF00699424
更新日期：1994-05-01 00:00:00
abstract：:Cryosurgery is one of the palliative treatment options to decrease local symptoms due to rectal carcinoma. A total of 106 patients (aged 45-92 years) underwent palliative cryosurgery for primary rectal cancer. Inclusion criteria were prohibitive surgical risk, unresectability, distant metastases, patient refusal of su...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s003840050206
更新日期：1999-08-01 00:00:00
abstract：INTRODUCTION:One of the main uses of robotic assisted abdominal surgery is the mesorectal excision in patients with rectal cancer. The aim of the present study is to analyse the learning curve for robotic assisted laparoscopic resection of rectal cancer. PATIENTS AND METHODS:We included in our study 43 consecutive rec...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-012-1620-6
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND AND AIMS:To study whether there are differences in the immunohistochemical staining of CD8, CD45R0, and CD68 of immune cells in regional lymph node metastases from colorectal cancer that are of potential interest in prognostic prediction. MATERIALS AND METHODS:Analysis of archival specimens from 93 patients...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840100337
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND AND AIMS:Evacuation disorders associated with a rectocele can be improved by rectocele repair. This study investigated whether anorectal function tests results change after rectocele repair. PATIENTS AND METHODS:Fourteen patients with 2nd or 3rd degree rectocele and evacuation disorder were treated by poste...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-002-0469-5
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:Whether the introduction of extralevator abdominoperineal excision (ELAPE) improves survival and safety remains controversial. We conducted a systematic review and meta-analysis of all comparative studies to define the efficacy and safety of ELAPE and standard abdominoperineal excision (APE). MATERIALS AND MET...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00384-013-1793-7
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Up to 25% of colorectal cancers present with bowel obstruction. Metal stents (MS) can provide a bridge to surgery by relieving obstruction and allowing the subject's condition to improve pre-operatively. METHODS:Hospital Episode Statistics (HES) is a database of all NHS funded secondary care episodes in Eng...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-019-03302-5
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:No consensus exists regarding the use of preoperative bowel preparation for patients undergoing a low anterior resection (LAR). Several comparative studies show similar outcomes when a single time enema (STE) is compared with mechanical bowel preparation (MBP). It is hypothesized that STE is comparable with MBP...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03651-6
更新日期：2020-10-01 00:00:00
abstract：INTRODUCTION:It is generally believed that resumption of feeding after colorectal resection is indicated only after recovery of bowel function. This study was designed to verify safety, feasibility, and tolerance of early oral postoperative feeding (EOF) outside an enhanced recovery after surgery (ERAS) program. MATER...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-011-1138-3
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to identify the size criteria of lateral lymph node metastasis in lower rectal cancer both in patients who underwent preoperative CRT and those who did not. METHODS:This study enrolled 150 patients who underwent resection for primary lower rectal adenocarcinoma with lateral lymph ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-017-2873-x
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:The aim of the study was to determine the spatiotemporal expression of Wnt5a during hindgut and anorectum development in human embryos and to explore the possible role of Wnt5a during the morphogenesis of the human hindgut and anorectum. MATERIALS AND METHODS:The embryos (n = 107) were sectioned serially and s...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1191-y
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND AND AIMS:We previously reported that the sole clinicopathological parameters of carcinomas diagnosed in a single institution in 1975 differed from those in patients diagnosed in 1995. The findings might be compatible with the loss of importance of the microsatellite instability of the carcinogenic pathway. ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-001-0373-4
更新日期：2002-05-01 00:00:00
abstract：BACKGROUND:Currently, many surgeons place a prophylactic drain in the abdominal or pelvic cavity after colorectal anastomosis as a conventional treatment. However, some trials have demonstrated that this procedure may not be beneficial to the patients. OBJECTIVE:To determine whether prophylactic placement of a drain i...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析
doi：10.1007/s00384-016-2509-6
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to assess the value of metastatic lymph node ratio (LNR) in predicting disease-free survival (DFS) in patients with stage III adenocarcinoma of the colon. MATERIALS AND METHODS:From 1995 to 2003 inclusively, a total of 624 patients featuring stage III adenocarcinoma of the colo...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-009-0738-7
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND AND AIMS:Colonic diverticulitis shows a high recurrence rate, but the role of faecal markers in predicting recurrence is unknown. The aim of this study was to investigate the role of faecal calprotectin (FC) in predicting recurrence of diverticulitis. PATIENTS/METHODS:A prospective cohort study was performe...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-014-1884-0
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:As angiogenesis is one of the key steps in tumor growth, invasion, and metastasis, antiangiogenic therapy is supposed to be an attractive approach for antitumor treatment. We investigated the cytotoxic, anti-adhesive, and anti-invasive effects of angiostatin in vitro and on intraperitoneal tumor growth in a ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-005-0040-2
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:This study evaluates the erectile function of male patients treated by preoperative radiotherapy followed by surgery and surgery alone for locally advanced rectal cancer. METHODS:A total of 112 men treated by total mesorectal excision with autonomic nerve preservation were included. Seventy-three patients were...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-0879-8
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:The prognostic significance of anti-53 autoantibody in colorectal cancer (CRC) patients is unclear due to measurement of overall rather than disease-specific survival and generally short follow-up periods in many studies. We aim to investigate prognostic significance of anti-p53 auto-antibodies in a study wi...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-008-0458-4
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-0952-3
更新日期：2010-12-01 00:00:00
abstract：:Twenty-one patients suffering from rectal prolapse (n = 15) or internal rectal procidentia (n = 6) were investigated clinically and by anorectal manometry prior to and six months following retopexy. Rectal prolapse was associated with incontinence in 67% (10/15) of the patients preoperatively. The moderately or severe...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF01649678
更新日期：1988-03-01 00:00:00
abstract：PURPOSE:The purpose of this study was to assess the effect of a structured hands-on workshop on the detection rate of obstetric anal sphincter injuries. METHODS:All physicians attending the delivery ward in our institution participated in a structured obstetric anal sphincter injury hands-on workshop developed by Dr. ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-015-2365-9
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:There is a growing literature on the significance of tumor-associated macrophages (TAMs) in colorectal cancer (CRC). However, the role of TAMs in predicting the prognosis of CRC remains controversial. The current study aims to determine the prognostic and clinicopathological value of different types and distrib...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s00384-020-03686-9
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to evaluate prospectively the functional outcome of posterior sagittal rectopexy with prolene mesh for rectal prolapse in young adults. PATIENTS AND METHODS:The study was carried out on 32 patients, 21 were males (65.63%) presented with complete rectal prolapse with a mean age of 3...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-010-0931-8
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND AND AIM:Data on maximum resting pressure (MRP) and maximum squeeze pressure (MSP) changes after hemorrhoidectomy are not univocal and follow-up of patients undergoing surgery is mostly short-lived. The aim of this study was to prospectively examine during 1-year follow-up the long-term manometric results of ...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-006-0174-x
更新日期：2007-03-01 00:00:00
abstract：PURPOSE:This study was designed to examine the impact of an omentoplasty and its quality on pelviperineal morbidity after abdominoperineal resection (APR) for rectal cancer. METHODS:This was a retrospective single-centre study of consecutive patients undergoing APR for primary or recurrent rectal cancer between 2000 a...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-019-03412-0
更新日期：2019-11-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00384-018-3139-y
更新日期：2018-10-01 00:00:00
abstract：:Flat-type colorectal tumors have are being detected with increasing frequency. It has become clear that these flat lesions contain two subtypes; flat-elevated and depressed lesions. However, their clinicopathological features and roles in colorectal carcinogenesis remain obscure. We classified colorectal adenomas and ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840000244
更新日期：2000-11-01 00:00:00
abstract：:An audit was performed of 77 patients with a single colorectal cancer visualised and sited before surgery by colonoscopic examination. The site of the cancer described at colonoscopy was compared with the actual site found at laparotomy. Six significant errors in preoperative localisation were encountered, when a chan...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF00298535
更新日期：1995-01-01 00:00:00
