Abstract:
:For 29 patients with congestive heart failure (CHF), 24-hour noninvasive ambulatory blood pressure (ABP) and heart rate (HR) measurement profiles were described, using the periodogram method, and were compared with the same findings in 22 matched controls. Right-sided heart catheterization was performed in all patients. The mean cardiac index was 2.2 L/min/m2 (range 1.3 to 2.9 L/min/m2). More severe CHF, as assessed by cardiac index, pulmonary artery wedge pressure, and right atrial pressure, correlated significantly with a reduction in the amplitude of the circadian ABP and HR rhythms (0.38 less than r less than 0.63; p less than 0.05). Moreover, a reduced increase in cardiac index during cycloergometric exercise in 11 CHF patients correlated with a blunting of the circadian systolic ABP and HR profiles (0.57 less than r less than 0.90; p less than 0.05). Our results indicate that there is a reduction in the amplitude of the circadian BP and HR rhythms related to the severity of CHF.
journal_name
Am Heart Jjournal_title
American heart journalauthors
van de Borne P,Abramowicz M,Degre S,Degaute JPdoi
10.1016/0002-8703(92)90710-dsubject
Has Abstractpub_date
1992-04-01 00:00:00pages
998-1004issue
4 Pt 1eissn
0002-8703issn
1097-6744pii
0002-8703(92)90710-Djournal_volume
123pub_type
杂志文章abstract::In 30 years of follow-up in the Framingham study, routine biennial ECG examinations revealed 315 subjects with ECG-LVH and 164 with unrecognized ECG-MI without previous cardiac explanation. Among subjects initially free of clinically evident coronary heart disease and both ECG abnormalities, the incidence of ECG-LVH w...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90156-0
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF) outcomes. However, TMAO is the final product of a complex metabolic pathway (ie, choline/carnitine) that has never been entirely investigated in HF. The present study investigates a panel of metabolites involved in...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2021.01.006
更新日期:2021-01-14 00:00:00
abstract:BACKGROUND:Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both associated with poor prognosis. Vitamin D may inhibit renin transcription and lower PRA. We investigated whether vitamin D3 (VitD3) supplementation lowers PRA in CHF patients. METHODS AND...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2013.05.009
更新日期:2013-08-01 00:00:00
abstract::Left ventricular (LV) outflow obstruction may result from retaining the anterior mitral leaflet when a mitral prosthesis is inserted in the mitral anulus. We retrospectively reviewed the echocardiograms (two-dimensional Doppler and Doppler color flow imaging, or transesophageal with color flow imaging) obtained in sev...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)91005-8
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:Weekly fish consumption has been related to a lower risk of fatal coronary heart disease (CHD) and incident stroke in populations with a low fish intake. This relation has mainly been attributed to n-3 fatty acids in fish, that is, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It is at present ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2009.12.033
更新日期:2010-04-01 00:00:00
abstract::To evaluate the mechanisms involved in nitrate tolerance, we randomized 23 patients with congestive heart failure resulting from coronary artery disease to an isosorbide dinitrate or a molsidomine infusion. The drugs were titrated to decrease pulmonary capillary wedge pressure by > or = 30% or > or = 10 mm Hg. Then is...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(94)90632-7
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Acute heart failure (AHF) remains a major public health burden with a high prevalence and poor prognosis. Relaxin is a naturally occurring peptide hormone that increases cardiac output, arterial compliance, and renal blood flow during pregnancy. The RELAX-AHF-1 study will evaluate the effect of RLX030 (recom...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2011.10.009
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:The contemporary magnitude and prognostic implications of complete heart block (CHB) in patients with acute myocardial infarction (AMI) are unknown. As part of a community-based study of patients hospitalized with AMI in the Worcester, MA, metropolitan area, changes over time in the incidence rates of CHB co...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2008.03.011
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Acute myocardial infarction (AMI) has become a major cause of hospitalization and mortality in China. There has been limited data to date available to characterize AMI presentation, contemporary patterns of medical care, and outcomes in China. AIMS:The CAMI Registry is a national project with the objectives...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2015.04.014
更新日期:2016-05-01 00:00:00
abstract::Even though congestive heart failure is extremely common, the mechanisms responsible for the clinical manifestations remain a puzzle. The central and autonomic (sympathetic) nervous systems are responsible for a large part of the clinical manifestations. The role of the nervous system in CHF is discussed briefly. It i...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90471-4
更新日期:1978-02-01 00:00:00
abstract::Flosequinan is an oral arterial and venous vasodilator that is currently under investigation for the treatment of congestive heart failure. The effects of flosequinan on ventricular performance and myocardial contractility were studied in 10 patients with severe congestive heart failure during right and left cardiac c...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90723-u
更新日期:1991-02-01 00:00:00
abstract::Left ventricular ejection fraction and regional wall motion were assessed by multigated equilibrium radionuclide ventriculography within 24 hours of onset of first acute transmural myocardial infarction (MI) in 32 patients. Abnormal left ventricular wall motion was noted in all 16 patients with anterior infarction and...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90644-0
更新日期:1983-11-01 00:00:00
abstract:OBJECTIVES:The DANHEART trial is a multicenter, randomized (1:1), parallel-group, double-blind, placebo-controlled study in chronic heart failure patients with reduced ejection fraction (HFrEF). This investigator driven study will include 1500 HFrEF patients and test in a 2 × 2 factorial design: 1) if hydralazine-isoso...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2020.09.020
更新日期:2021-01-01 00:00:00
abstract::The aim of this study was to determine whether paroxysmal atrial fibrillation (PAF) and/or restoration to sinus rhythm with electric or pharmacologic cardioversion induce modifications to the coagulation system. Thirty-five patients with PAF undergoing either electric (n = 11) or pharmacologic (n = 24) cardioversion w...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.108520
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Female sex independently predicts bleeding risk after percutaneous coronary intervention (PCI). Bivalirudin is safer than abciximab plus heparin in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Thus, a greater benefit of bivalirudin in women would be expected. METHODS:We performed a...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2012.12.021
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Acute pericarditis is common, yet uncertainty persists on its treatment. We thus aimed to conduct a comprehensive systematic review on pharmacologic treatments for acute or recurrent pericarditis. METHODS:Controlled clinical studies were searched in several databases and were included provided they focused ...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2010.06.015
更新日期:2010-10-01 00:00:00
abstract::In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90662-5
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Ibutilide is indicated for the acute termination of atrial fibrillation and atrial flutter. Recent work concludes that ibutilide activates a late inward sodium current that is blocked by nifedipine. Because calcium channel blockers are commonly used in patients with atrial fibrillation, it is important to ex...
journal_title:American heart journal
pub_type: 杂志文章,meta分析
doi:10.1067/mhj.2002.120156
更新日期:2002-01-01 00:00:00
abstract::CHD remains the leading cause of death in most developed countries; therefore, elucidation of risk factors and associated mechanisms for atherosclerosis and development of CHD has been a high priority. Data from the Framingham Heart Study and other large-scale epidemiologic studies have identified major risk factors a...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/s0002-8703(96)90096-4
更新日期:1996-06-01 00:00:00
abstract::To identify a method for characterizing the dynamic behavior of ventricular arrhythmias at different heart rates, 201 consecutive patients with frequent premature ventricular contractions (PVCs) underwent two 24-hour electrocardiographic monitoring periods. The percentage of PVCs for each cycle length was calculated a...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(97)70203-5
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:In a previous study from a single center, radionuclide measures of collateral flow with technetium 99m sestamibi have been shown to be significantly associated with angiographic residual (antegrade and collateral) flow and independent predictors of final infarct size in acute myocardial infarction. This stud...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/s0002-8703(97)70046-2
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:A high fasting glucose level may be a marker not only for microvascular complications, but also for macrovascular complications. We evaluated the clinical significance of a high fasting glucose level (> or =110 mg/dL), detected either at baseline or during follow-up, in the Bezafibrate Infarction Prevention ...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ahj.2003.09.013
更新日期:2004-02-01 00:00:00
abstract::This study prospectively assessed the electrophysiologic effects of parenteral magnesium sulfate administration on paroxysmal atrioventricular (AV) reentrant supraventricular tachycardia and the efficacy of magnesium to terminate these arrhythmias. Eleven normomagnesemic patients, seven with orthodromic reentrant supr...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(05)80021-3
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:In patients with acute myocardial infarction (AMI), depressive symptoms increase the risk for cardiac events. Recently, the S allele of the serotonin transporter (5-HTT) gene-linked polymorphic region was shown to reduce transcription of this gene and thus reduce serotonin reuptake, and this allele is linked...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.03.062
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Older adults presenting with acute myocardial infarction (MI) often have multivessel coronary artery disease amenable to percutaneous coronary intervention (PCI), yet the risks of multivessel intervention may outweigh potential benefits in these patients. We sought to determine if nonculprit intervention dur...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2015.10.017
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Bleeding is associated with adverse outcome in acute coronary syndromes. However, the precise pathophysiologic mechanisms have not been elucidated. We sought to determine the relationship between bleeding and myocardial ischemia detected by concurrent continuous electrocardiogram (ECG) monitoring and their i...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2008.05.022
更新日期:2008-10-01 00:00:00
abstract::This study investigated the correlation between cardiac abnormalities and cytosine-thymine-guanine (CTG) trinucleotide repeat expansion in patients with myotonic dystrophy (MD). We studied 18 patients with the adult form of classical MD and 18 age-matched control subjects. In patients with MD, left ventricular systoli...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(97)70137-6
更新日期:1997-08-01 00:00:00
abstract::Minnesota codes (MC), expressing Q-QS, ST segment, and T wave abnormalities in ECGs taken during the acute event and at a 1-year follow-up were studied in 256 survivors of myocardial infarction (MI). On the 1-year ECGs large Q waves (MC 1.1) were more common in patients with a history of previous MI than in those with...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90141-9
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Practice guidelines for patients with non-ST-segment elevation (NSTE) acute coronary syndromes (ACS) recommend targeting evidence-based therapies for the highest-risk patients. We characterized guideline adherence for NSTE ACS by risk status. METHODS:We analyzed inhospital treatments and outcomes for 77760 ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.08.006
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:A shortcoming of the pediatric electrocardiogram (ECG) appears to be its inability to accurately detect left ventricular hypertrophy (LVH). This study prospectively assesses the usefulness of the pediatric ECG as a screening modality for LVH. METHODS:Concomitant echocardiograms and ECGs from a large cohort ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1067/mhj.2003.15
更新日期:2003-04-01 00:00:00