Microparticle-enhanced nephelometric immunoassay for human C-reactive protein.

abstract：BACKGROUND:This study aimed to determine whether CD44 polymorphisms were correlated with hepatocellular carcinoma (HCC) and to reveal a new potential target for early prediction, prevention, and diagnosis of HCC. METHOD:This study involved 96 cases with chronic hepatitis B (CHB), 96 cases with hepatitis B virus-relate...

journal_title：Journal of clinical laboratory analysis

authors： Deng Y,Chen ZJ,Lan F,He QT,Chen SY,Du YF,Li S,Qin X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Non-acrocentric satellited chromosomes mostly result from familial balanced insertions or translocations with p12 or p13 of any acrocentric. Although all non-acrocentrics have been involved, only 12 instances of chromosome 6 involvement are known. CASE PRESENTATION:A female infant exhibited clinical feature...

journal_title：Journal of clinical laboratory analysis

authors： Domínguez MG,Rivera H,Dávalos-Pulido RM,Dávalos-Rodríguez IP

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) study plays an important role as initial investigation specimen of lymphoma as well as staging lymphoma. This study aimed to investigate the utility of BM studies for classification of lymphoma and evaluate features of BM involvement by lymphoma over a period of 11 years. METHODS:A total of...

journal_title：Journal of clinical laboratory analysis

authors： Kwoun WJ,Ahn JY,Park PW,Seo YH,Kim KH,Seo JY,Lee HT,Yoo KH

更新日期：2019-05-01 00:00:00

abstract：:Didemnin A was conjugated at the amino terminus of the N-methylleucine residue, via the linkers N-succinimidyl-3-(2-pyridyldithio)-propionate and trans-1,4-maleimidomethyl-cyclohexane carboxylic acid, to keyhole limpet hemocyanin (KLH) and bovine serum albumin (BSA). The didemnin-KLH conjugates were used to hyperimmun...

journal_title：Journal of clinical laboratory analysis

authors： Raybould TJ,Grothaus PG,Simpson SB,Bignami GS,Lazo CB,Newman RA

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Accumulated evidences indicate that long non-coding RNAs (lncRNAs) participate in many biological mechanisms. Moreover, it acts as an essential regulator in various human diseases such as gastric cancer (GC). Nevertheless, the comprehensive regulatory roles and clinical significance of most lncRNAs in GC are...

journal_title：Journal of clinical laboratory analysis

authors： Zhu Y,Luo C,Korakkandan AA,Fatma YHA,Tao Y,Yi T,Hu S,Liao Q

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Diverse and circumstantial evidence suggests that schizophrenia is a neurodevelopmental disorder. Genes contributing to neurodevelopment may be potential candidates for schizophrenia. The human SOX11 gene is a member of the developmentally essential SOX (Sry-related HMG box) transcription factor gene family ...

journal_title：Journal of clinical laboratory analysis

authors： Sun CP,Sun D,Luan ZL,Dai X,Bie X,Ming WH,Sun XW,Huo XX,Lu TL,Zhang D

更新日期：2020-08-01 00:00:00

abstract：:Several retrospective studies have shown that a high level of microsatellite instability (MSI-H) is an important prognostic factor of a more favorable outcome in stage II and III colorectal cancer (CRC) patients. In this study, three commonly used polymerase chain reaction (PCR)-based MSI analysis techniques were comp...

journal_title：Journal of clinical laboratory analysis

authors： Deschoolmeester V,Baay M,Wuyts W,Van Marck E,Pelckmans P,Lardon F,Vermorken JB

更新日期：2006-01-01 00:00:00

abstract：:An immunoenzymometric assay (IEMA) for a new CA125-like antigen, CA602, was developed. Five monoclonal antibodies raised against a human ovarian carcinoma cell line could detect their respective antigens in the sera of ovarian carcinoma patients. The antigen levels detected in serum by the various antibodies correlate...

journal_title：Journal of clinical laboratory analysis

authors： Mochizuki H,Sato I,Nagoya K,Furusako S,Yamauchi T,Masuko H,Sato H,Morishita H,Yajima M,Sasaki H

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Wolfram's syndrome (WFS) is a hereditary (autosomal recessive) neurodegenerative disorder. The clinical features are related to diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD) with other variable clinical manifestations. Pathogenic variants in the WFS1 gene, encoding wolframin, a...

journal_title：Journal of clinical laboratory analysis

authors： Torkamandi S,Rezaei S,Mirfakhraie R,Bayat S,Piltan S,Gholami M

更新日期：2020-08-01 00:00:00

abstract：AIM:The present study aimed to investigate associations of the platelet-to-white blood cell ratio (PWR)-a novel hematological indicator of inflammatory responses-with 30-day outcomes in patients with HBV-associated decompensated cirrhosis (HBV-DeCi). METHODS:We recruited 131 patients with HBV-DeCi for this retrospecti...

journal_title：Journal of clinical laboratory analysis

authors： Zhang J,Qiu Y,He X,Mao W,Han Z

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:After hematopoietic stem cell transplantation (HSCT), early detection of engraftment would be of critical value for clinicians. The aim of this study was to identify faster parameters for engraftment. METHODS:We evaluated blood cell parameters including complete blood count (CBC), differential counts, and v...

journal_title：Journal of clinical laboratory analysis

authors： Yahng SA,Lee JW,Kim Y,Kim M,Oh EJ,Park YJ,Lee JW,Cho B,Han K

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) was the second leading cause of death for the past 3 years in Taiwan. The insulin-like growth factor (IGF) system is considered a new risk factor of CAD because investigations show that the levels and bioactivity of IGF-I and IGFBP-3 (where IGFBP is insulin-like growth factor-bi...

journal_title：Journal of clinical laboratory analysis

authors： Lin HL,Ueng KC,Wang HL,Chen TP,Yang SF,Chu SC,Hsieh YS

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the value of biochemical profile of cyst fluid and diffusion-weighted imaging (DWI) in differentiating hepatic hydatid cysts (HCs) from liver simple cysts. MATERIALS AND METHODS:Forty-six patients underwent MR imaging. Twenty-nine patients had 29 hydatid cysts and 17 pa...

journal_title：Journal of clinical laboratory analysis

authors： Shanshan W,Hui L,Yan L,Li W,Yongfang R,Yan W,Kader M,Wenxiao J

更新日期：2018-01-01 00:00:00

abstract：:N-terminal pro-brain natriuretic peptide (NT-proBNP) and BNP measurement could have a significant role in differentiating dyspnea between cardiac or pulmonary origin in the emergency room. The development of new and different commercial assays for these B-type natriuretic peptides offers the possibility of improving a...

journal_title：Journal of clinical laboratory analysis

authors： Sanz MP,Borque L,Rus A,Vicente B,Ramírez Y,Lasa L

更新日期：2006-01-01 00:00:00

abstract：:We evaluated the Miles Inc., Clinitek Atlas Automated Urine Chemistry Analyzer for 11 tests: bilirubin, color, glucose, ketones, leukocyte esterase, nitrite, occult blood, pH, protein, specific gravity, and urobilinogen. The instrument uses a roll of reagent strips affixed to a clear plastic support; urine specimens a...

journal_title：Journal of clinical laboratory analysis

authors： Lott JA,Johnson WR,Luke KE

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:(a) To evaluate the clinical performance of endocrine analytes using the sigma metrics (σ) model. (b) To redesign quality control strategies for performance improvement. METHODS:The sigma values of the analytes were initially evaluated based on the allowable total error (TEa), bias, and coefficient of varia...

journal_title：Journal of clinical laboratory analysis

authors： Liu Y,Cao Y,Liu X,Wu L,Cai W

更新日期：2020-09-20 00:00:00

abstract：BACKGROUND:Inflammation plays an important role in the development and progression of CRC. The members of inflammatory biomarkers, preoperative NLR and PLR, have been proved by numerous studies to be promising prognostic biomarkers for CRC. However, the diagnostic value of the two biomarkers in CRC remains unknown, and...

journal_title：Journal of clinical laboratory analysis

authors： Peng HX,Yang L,He BS,Pan YQ,Ying HQ,Sun HL,Lin K,Hu XX,Xu T,Wang SK

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Cell-free DNA (cfDNA) circulating in blood is currently used for noninvasive diagnostic and prognostic tests. Minimizing background DNA is vital for detection of low abundance cfDNA. We investigated whether a new blood collection device could reduce background levels of genomic DNA (gDNA) in plasma compared ...

journal_title：Journal of clinical laboratory analysis

authors： Norton SE,Luna KK,Lechner JM,Qin J,Fernando MR

更新日期：2013-07-01 00:00:00

abstract：:p21, an important regulator of the cell cycle, acts as a mediator of the growth-suppressing and -promoting functions of p53. We aimed to investigate the association between codon 31 polymorphisms of p21 gene and endometriosis. Women were divided into two groups: endometriosis (n = 102) and nonendometriosis (n = 119). ...

journal_title：Journal of clinical laboratory analysis

authors： Hsieh YY,Tsai FJ,Chang CC,Chen WC,Tsai CH,Tsai HD,Lin CC

更新日期：2001-01-01 00:00:00

abstract：:The proteoglycan decorin inhibits TGF-beta; therefore, it could antagonize progression of fibrotic diseases associated with activation of TGF-beta(1). The effect of decorin transfection in human mesangial cells (HMCs) on the expression of genes related to kidney fibrosis was investigated. HMCs, isolated from glomeruli...

journal_title：Journal of clinical laboratory analysis

authors： Costacurta A,Priante G,D'Angelo A,Chieco-Bianchi L,Cantaro S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Spinal tuberculosis is the most common form of musculoskeletal tuberculosis. The expression of matrix metalloproteinase-1 (MMP-1) is increased in cells with Mycobacterium tuberculosis infection. MMP-1 plays a curial role in extracellular matrix degradation during the progression of tuberculosis. Although the...

journal_title：Journal of clinical laboratory analysis

authors： Zhou Y,Gao Q,He D,Deng A,Huang R,Li Y,Tan C,Guo C,Guo Q,Wang L,Yang G,Zhang H

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To explore the clinical value of serum IgM and IgG to SARS-CoV-2 in COVID-19. METHODS:105 COVID-19 patients were enrolled as the disease group. 197 non-COVID-19 patients served as the control group. Magnetic chemiluminescent immunoassay (MCLIA) was used to detect the IgM and IgG. RESULTS:The peak of positiv...

journal_title：Journal of clinical laboratory analysis

authors： Wu LX,Wang H,Gou D,Fu G,Wang J,Guo BQ

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Essential trace elements are vital to human health. In this study, our aim was to establish reference intervals of and to evaluate relationships among Ca, Fe, Cu, Mg, and Zn for children. METHODS:We collected blood samples of 3210 children aged 0-14 years from Lu'an, China, and concentrations of the above e...

journal_title：Journal of clinical laboratory analysis

authors： Zhai R,Zhang M,Liu J,Guang H,Li B,Chen D,Zhang S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Though recent reports have indicated a higher prevalence of latent tuberculosis infection (LTBI) in laboratory personnel than in other healthcare workers, these studies included only a limited number of laboratory personnel. METHODS:We have thus focused on the laboratory personnel, who had a high level of e...

journal_title：Journal of clinical laboratory analysis

authors： Moon HW,Kim H,Hur M,Yun YM,Lee A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:This study was performed to compare the clinical efficacies of anterior cruciate ligament (ACL) reconstruction with autologous ligament grafting at different time points. METHODS:Eighty-five patients with ACL were categorized into two groups: Group A (GA, n = 45), who underwent early-stage (≤3 weeks) surger...

journal_title：Journal of clinical laboratory analysis

authors： Hu B,Gao F,Li C,Zhang B,An M,Lu M,Liu Y,Liu Y

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) is a critical condition characterized by bilateral pulmonary infiltrates and severe hypoxemia. This study aimed to evaluate the diagnostic and prognostic values of Club cell protein 16 (CC16) in critical care patients with ARDS. METHODS:In this retrospective observ...

journal_title：Journal of clinical laboratory analysis

authors： Lin J,Zhang W,Wang L,Tian F

更新日期：2018-02-01 00:00:00

abstract：:Multidrug resistance (MDR) is a multifactorial phenomenon and the role of these proteins in generating the MDR phenotype is controversial. With this in mind, this review compiled the current data on the role of ABCB1, ABCC1, and LRP proteins in the prognosis of hematologic neoplasms and their influence on the choice o...

journal_title：Journal of clinical laboratory analysis

authors： de Moraes AC,Maranho CK,Rauber GS,Santos-Silva MC

更新日期：2013-01-01 00:00:00

abstract：:Premortem diagnosis of the DiGeorge syndrome and its partial variants relies on the demonstration of a primary defect in cell-mediated immunity, generally in the setting of an infant with congenital heart disease, hypocalcemia, absence of a thymic shadow, and typical dysmorphic features. Although T-cell enumeration is...

journal_title：Journal of clinical laboratory analysis

authors： Slade HB,Greenwood JH,Beekman RH 3rd,McCoy JP Jr,Hudson JL,Pahwa S,Schwartz SA

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To explore the role of serum periostin in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHOD:We conducted a retrospective study and 124 aSAH patients treated in Shenzhen People's hospital during March 1st 2015 to December 30th 2016 were included. Baseline information, neurological status and cli...

journal_title：Journal of clinical laboratory analysis

authors： Luo W,Wang H,Hu J

更新日期：2018-06-01 00:00:00

abstract：:Mycobacterium avium is an important intracellular pathogen, particularly in AIDS patients. It also shows the second frequency among nontuberculous mycobacteria infections in Korea. Point mutations of domain V region of the 23S rRNA gene has been known to confer clarithromycin resistance to M. avium. In order to isolat...

journal_title：Journal of clinical laboratory analysis

authors： Lee SH,Park YK,Kim CK,Kim HJ

更新日期：2011-01-01 00:00:00