Platelet-to-white blood cell ratio: A novel and promising prognostic marker for HBV-associated decompensated cirrhosis.

abstract：BACKGROUND:Alport syndrome (ATS) is a hereditary nephritis with hereditary and clinical heterogeneity; the early clinical symptoms are atypical, which can easily lead to misdiagnosis. The proband, a 6-year-old girl, was found to have microscopic hematuria, proteinuria, and visual impairment at about 5 years old; the re...

journal_title：Journal of clinical laboratory analysis

authors： Zhu Q,Zhou C,Wang J

更新日期：2020-09-06 00:00:00

abstract：BACKGROUND:The aim of this study was to detect reliability of Brucella Coombs gel test (BCGT) by comparing with with ELISA (IgG + IgM), Standard agglutination test, and Brucella immunocapture agglutination methods in serological diagnosis of brucellosis. METHODS:Brucella Coombs gel test (BCGT), Brucella ELISA (IgG + I...

journal_title：Journal of clinical laboratory analysis

authors： Kalem F,Ergün AG,Durmaz S,Doğan M,Ertuğrul Ö,Gündem S

更新日期：2016-09-01 00:00:00

abstract：:There is an increasing demand for genetic testing of patients with hypercoagulability. We have developed a multiplex-polymerase chain reaction (PCR) technique that incorporates the state-of-the art of genetic testing for thrombosis mutations (Factor V Leiden [FVL] and G20210A F2 and C46T F12). The sequences are detect...

journal_title：Journal of clinical laboratory analysis

authors： López M,Giraldo P,Alvarez P,Cornudella R,Pocoví M,Martínez A,Fontcuberta J,Soria JM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) abnormalities are a group of serious birth defects associated with high rates of stillbirths, infant death, or abnormal development, and various disease-causing copy number variations play a much more important role in the etiology of CNS abnormalities. This study intends to pres...

journal_title：Journal of clinical laboratory analysis

authors： Song T,Xu Y,Li Y,Jia L,Zheng J,Dang Y,Wan S,Zheng Y,Zhang J,Yang H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:We evaluated the new body fluid module on Sysmex UF1000-i (UF1000i-BF) for analysis of white blood cell (WBC) and red blood cell (RBC) in cerebrospinal fluid (CSF). METHODS:WBC and RBC counting were compared between UF1000i-BF and Fuchs-Rosenthal counting chamber in 67 CSF samples. This study also included ...

journal_title：Journal of clinical laboratory analysis

authors： Buoro S,Apassiti Esposito S,Alessio M,Crippa A,Ottomano C,Lippi G

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Donor-specific anti-human leukocyte antigen (HLA) antibodies (DSAs) in recipients is a risk factor for donor stem cell graft failure in haploidentical hematopoietic stem cell transplantation (haplo-HSCT), and the treatment to reduce the levels of DSAs is not unanimous. This study was to analysis the role of ...

journal_title：Journal of clinical laboratory analysis

authors： Zhang R,He Y,Yang D,Jiang E,Ma Q,Pang A,Zhai W,Wei J,Feng S,Han M

更新日期：2020-07-01 00:00:00

abstract：:Apoptosis of epithelial hepatocytes plays a pivotal role in acute as well as in chronic liver diseases. The cleavage of cytokeratin-18 (CK-18) by caspases is an early event in the apoptotic process. We therefore sought to investigate serum levels of CK-18 and 20S proteasome in patients with liver cirrhosis, primary gr...

journal_title：Journal of clinical laboratory analysis

authors： Hetz H,Hoetzenecker K,Hacker S,Faybik P,Pollreisz A,Moser B,Roth G,Hoetzenecker W,Lichtenauer M,Klinger M,Krenn CG,Ankersmit HJ

更新日期：2007-01-01 00:00:00

abstract：:A novel severe acute respiratory syndrome-associated coronavirus (SARS-CoV) has been discovered. The detection of both antigens and antibodies in SARS-CoV from human specimens with suspected SARS plays an important role in preventing infection. We developed a novel rapid immunochromatographic test (RICT) based on the ...

journal_title：Journal of clinical laboratory analysis

authors： Kogaki H,Uchida Y,Fujii N,Kurano Y,Miyake K,Kido Y,Kariwa H,Takashima I,Tamashiro H,Ling AE,Okada M

更新日期：2005-01-01 00:00:00

abstract：:Circulating bilirubin is thought to function as a physiological antioxidant. One of the decomposition products of this process is the biopyrrins, which include two regioisomers: biotripyrrin-a (1,14,15,17-tetrahydro-2,7,13-trimethyl-1,14-deoxy-3-vinyl-16H-tripyrrin-8,12-dipropionic acid) and biotripyrrin-b (1,14,15,17...

journal_title：Journal of clinical laboratory analysis

authors： Ihara H,Matsumoto T,Morita Y,Hirano A,Okada M,Hashizume N,Shioji I,Yoshimura H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:So far, there has been no tool to estimate activity at diagnosis and predict all-cause mortality in patients with ANCA-associated vasculitis (AAV). Hence, we determined the initial predictors of them in patients with AAV. METHODS:We retrospectively reviewed the medical records of 182 patients with AAV. Seve...

journal_title：Journal of clinical laboratory analysis

authors： Kim MK,Choi H,Kim JY,Song JJ,Park YB,Lee SW

更新日期：2020-01-01 00:00:00

abstract：:The incidence of aneuploidy was determined by flow cytometric analysis in paraffin-embedded tumor samples of 125 patients with non-Hodgkin lymphoma (NHL). There were 48 low-grade (LG) and 77 high-grade (HG) tumors. Aneuploidy was found in 34 (27%) NHL, 15 (31%) LG, and 19 (25%) HG tumors. The analysis of patient survi...

journal_title：Journal of clinical laboratory analysis

authors： Vucković J,Forenpoher G,Marusić M,Uzarević B,Sabioncello A,Stula N,Dubravcić M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Prototheca species are a group of organisms ubiquitously existing in nature but have become a pathogenic threat to public health, which has aroused wide attention. Species identification and antifungal susceptibility have essential and valuable meanings to clinical diagnosis and treatment. METHODS:A case of...

journal_title：Journal of clinical laboratory analysis

authors： Zhao F,Chen M,Fu Y

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) was the second leading cause of death for the past 3 years in Taiwan. The insulin-like growth factor (IGF) system is considered a new risk factor of CAD because investigations show that the levels and bioactivity of IGF-I and IGFBP-3 (where IGFBP is insulin-like growth factor-bi...

journal_title：Journal of clinical laboratory analysis

authors： Lin HL,Ueng KC,Wang HL,Chen TP,Yang SF,Chu SC,Hsieh YS

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Aberrant levels of circulating microRNAs (miRNAs) are potential biomarkers in papillary thyroid carcinoma (PTC) diagnosis and therapy. The aim of this study was to evaluate serum exosomal miR-29a expression as a non-invasive biomarker for PTC diagnosis and prognosis. METHODS:Quantitative reverse transcripti...

journal_title：Journal of clinical laboratory analysis

authors： Wen Q,Wang Y,Li X,Jin X,Wang G

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:The non-invasive diagnostic approach for early detection of endometrial cancer (EC) remains limited. To date, human epididymis protein 4 (HE4) has been intensively studied but its diagnostic is controversial in EC. DJ-1 is an oncoprotein secreted by cancer cells, recently identified as a potential diagnostic...

journal_title：Journal of clinical laboratory analysis

authors： Benati M,Montagnana M,Danese E,Paviati E,Giudici S,Ruzzenente O,Franchi M,Lippi G

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Delta neutrophil index (DNI) is a new inflammatory marker and the present study aimed to evaluate the predictive value of the DNI for the presence of a perforation in elderly with acute appendicitis. METHODS:This retrospective observational study was conducted on 108 consecutive elderly patients (≥65 years ...

journal_title：Journal of clinical laboratory analysis

authors： Shin DH,Cho YS,Kim YS,Ahn HC,Oh YT,Park SO,Won MH,Cho JH,Kim YM,Seo JY,Lee YH

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Though recent reports have indicated a higher prevalence of latent tuberculosis infection (LTBI) in laboratory personnel than in other healthcare workers, these studies included only a limited number of laboratory personnel. METHODS:We have thus focused on the laboratory personnel, who had a high level of e...

journal_title：Journal of clinical laboratory analysis

authors： Moon HW,Kim H,Hur M,Yun YM,Lee A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The HER2 (human epidermal growth factor receptor-2) Ile655Val (rs1136201) genetic polymorphism can alter the receptor structure and its auto-activation, which can modify the signal transduction and, consequently, the cell cycle regulation. For this reason, this polymorphism has been extensively investigated ...

journal_title：Journal of clinical laboratory analysis

authors： de Almeida FC,Banin Hirata BK,Ariza CB,Losi Guembarovski R,de Oliveira KB,Suzuki KM,Guembarovski AL,Oda JMM,Vitiello GAF,Watanabe MAE

更新日期：2018-07-01 00:00:00

abstract：:The use of serum alkaline phosphatase (ALP) isoenzymes as markers of breast cancer metastases and treatment efficacy has received little attention. Twenty-six breast cancer women (56+/-13 years, all post-menopausal) were prospectively evaluated during their first and third course of chemotherapy (4-week interval). Ser...

journal_title：Journal of clinical laboratory analysis

authors： Le Bricon T,Gay-Bellile C,Cottu P,Benlakehal M,Guillon H,Houzé P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the relationship between HbA1c and RBC aggregation in type 2 diabetes mellitus (T2DM) patients by analysis of data from routine clinical tests and from in vitro experiments. METHODS:A total of 2,111 inpatients with type 2 diabetes were selected and among them, 364 patients (G...

journal_title：Journal of clinical laboratory analysis

authors： Li Q,Li L,Li Y

更新日期：2015-09-01 00:00:00

abstract：:As several possible prognostic and therapeutic applications of interleukin-6 are currently under trial, the available methods for its quantification in biological fluids should be evaluated. In this report, the 7TD1 hybridoma bioassay is compared to an enzyme immunoassay for the determination of interleukin-6 in serum...

journal_title：Journal of clinical laboratory analysis

authors： Papadopoulos NG,Dedoussis GV,Baxevanis CN,Papamichail M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the global mortality diseases and has a poor prognosis due to the lack of ideal tumor biomarkers. Circular RNAs (circRNAs) are an abundant kind of endogenous RNAs that recently are found play a crucial role in the cancer occurrence and development. Nevertheless, little is known ...

journal_title：Journal of clinical laboratory analysis

authors： Yu X,Ding H,Yang L,Yu Y,Zhou J,Yan Z,Guo J

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Sex-determining region Y-box 30 (SOX30) suppresses progression of several cancers, whereas its role in breast cancer is unclear. Therefore, we aimed to determine the correlation of SOX30 with tumor characteristics and prognosis in breast cancer patients. METHODS:The tumor samples of 510 breast cancer patient...

journal_title：Journal of clinical laboratory analysis

authors： Peng H,Luo Y,Wu J,Yin W

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Identification of dermatophytes at the species level, relying on macro- and microscopic properties of the colonies is time-consuming, questioned in many circumstances, and requires considerable expertise. In this study, we examined the potency of a new genetic marker, β-tubulin (BT2) gene, for differentiatio...

journal_title：Journal of clinical laboratory analysis

authors： Abastabar M,Mirhendi H,Rezaei-Matehkolaei A,Shidfar MR,Kordbacheh P,Makimura K

更新日期：2014-03-01 00:00:00

abstract：:Vitamin D plays a vital role not only in bone health but also in pathophysiology of many other body functions. In recent years, there has been significant increase in testing of 25-hydroxyvitamin D (25-OH vitamin D), a marker of vitamin D deficiency. The most commonly used methods for the measurement of 25-OH vitamin ...

journal_title：Journal of clinical laboratory analysis

authors： Garg U,Munar A,Frazee C 3rd,Scott D

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The many techniques used to diagnose the Factor V Leiden (FVL) mutation, the most common hereditary hypercoagulation disorder in Eurasians, and the most frequently requested genetic test reflect the evolving strategies in protein and DNA diagnosis. METHODS:Here, molecular methods to diagnose the FVL mutatio...

journal_title：Journal of clinical laboratory analysis

authors： Oh H,Smith CL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:MicroRNAs play a vital role in coronary artery disease. Abnormal expression of microRNAs has been found to be associated with the occurrence of CAD. METHODS:We identified significantly differentially expressed microRNAs in plasma between 40 patients with CAD and 10 controls with NCA using RNA sequencing. Th...

journal_title：Journal of clinical laboratory analysis

authors： Zhong Z,Zhong W,Zhang Q,Zhang Q,Yu Z,Wu H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The study evaluated the impact of interferences on the analytical specificity of three commercial and commonly used creatinine methods (two Jaffe and one enzymatic). METHODS:Manufacturer creatinine methods plus modified methods were tested with the following interferences: spiking serum with bilirubin, albu...

journal_title：Journal of clinical laboratory analysis

authors： Srisawasdi P,Chaichanajarernkul U,Teerakanjana N,Vanavanan S,Kroll MH

更新日期：2010-01-01 00:00:00

abstract：:Diurnal variations in the excretion of bone resorption markers were assessed in order to identify the type of urine collection which provides the most information on bone resorption rate and its relation to measuring bone dynamics in a postmenopausal population. Sixty women, ages 43-67 and without disease or treatment...

journal_title：Journal of clinical laboratory analysis

authors： Zaninotto M,Bernardi D,Ujka F,Bonato P,Plebani M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a popular arthrosis featured as pain, limited joint activity, and deformity. Cyclooxygenase-2 (COX-2) has been reported to be up-regulated in arthritic tissues and is integral to the progression of osteoarthritis (OA). Previous studies showed the COX-2 promoter G-765C polymorphism coul...

journal_title：Journal of clinical laboratory analysis

authors： Huang W,Deng C,Tian F,Gao W,Ding Z,Rao X,Yin Z

更新日期：2018-07-01 00:00:00