Abstract：
BACKGROUND:Though recent reports have indicated a higher prevalence of latent tuberculosis infection (LTBI) in laboratory personnel than in other healthcare workers, these studies included only a limited number of laboratory personnel. METHODS:We have thus focused on the laboratory personnel, who had a high level of exposure to specimens from patients with TB. We recruited 173 laboratory personnel and performed QuantiFERON-TB Gold In-Tube test (QFT-G) and tuberculin skin test (TST). RESULTS:QFT-G was positive in 21.4% of the enrolled laboratory personnel, and TST was positive in 33.3%. The agreement between the two tests was fair (κ = 0.234). In multivariate analyses, household contactwith TBpatients (P = 0.013), the laboratory sections of microbiology (P = 0.045) and chemistry/immunology (P = 0.014) were shown to be significantly associated with positive QFT-G results. CONCLUSION:Our data show a high prevalence of TST and QFT-G positivity in laboratory personnel and emphasize the importance of LTBI screening for laboratory personnel. In BCG-vaccinated populations with an intermediate incidence setting, QFT-G seems to be superior to TST as a screening tool for the detection of LTBI. Further study, including results of follow-up tests will be helpful for confirmation of our findings.
journal_name
J Clin Lab Analjournal_title
Journal of clinical laboratory analysisauthors
Moon HW,Kim H,Hur M,Yun YM,Lee Adoi
10.1002/jcla.20479subject
Has Abstractpub_date
2011-11-01 00:00:00pages
382-8issue
6eissn
0887-8013issn
1098-2825journal_volume
25pub_type
杂志文章abstract：:Our objectives in this study were to compare results obtained by an enzyme immunoassay (EIA) for F-actin antibody (FAA) immunoglobulin G (IgG) to those determined by an indirect fluorescent antibody (IFA) assay for smooth muscle antibody (SMA) IgG, and to determine the prevalence of FAA in patient sera having serologi...
journal_title：Journal of clinical laboratory analysis
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abstract：:The detection of hepatitis C virus (HCV) RNA by nucleic acid amplification techniques is the method of choice to differentiate between ongoing and past infection, and can be used to monitor the course of HCV infection. In this study, we evaluated the performance characteristics of a newly developed transcription-media...
journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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doi：10.1002/jcla.1860060509
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
doi：10.1002/jcla.1860060106
更新日期：1992-01-01 00:00:00
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
doi：10.1002/jcla.1860050407
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abstract：BACKGROUND:Non-acrocentric satellited chromosomes mostly result from familial balanced insertions or translocations with p12 or p13 of any acrocentric. Although all non-acrocentrics have been involved, only 12 instances of chromosome 6 involvement are known. CASE PRESENTATION:A female infant exhibited clinical feature...
journal_title：Journal of clinical laboratory analysis
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更新日期：2020-08-01 00:00:00
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journal_title：Journal of clinical laboratory analysis
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doi：10.1002/jcla.21914
更新日期：2016-09-01 00:00:00
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
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journal_title：Journal of clinical laboratory analysis
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doi：10.1002/jcla.20401
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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journal_title：Journal of clinical laboratory analysis
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更新日期：2019-05-01 00:00:00
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journal_title：Journal of clinical laboratory analysis
pub_type： 杂志文章
doi：10.1002/jcla.22581
更新日期：2018-10-01 00:00:00
